Abstract: An artificial blood vessel is formed of a tubular body of composite fibers. The composite fibers are composed of a polyethylene terephthalate and a polyester elastic body which are materials familiar with the tissue of an organism. The tubular body is produced by weaving, knitting or assembling processing, or the combined processing thereof, of the composite fibers.

Abstract: A vascular prosthesis is disclosed which excels in expansibility and allows satisfactory attachment thereto of cells and tissues. This vascular prosthesis is obtained by air-jet entangling a mass of yarns containing in at least a part thereof an elastic bulked yarn in order to get an entangled yarn furnished with fine crimps formed in fiber thereof, and fabricating a tubular fabric of the entangled fiber by one treatment selected from among weaving, knitting, and braiding treatments.

Abstract: Cell-penetrable medical material made of denatured collagen which is prepared by heating, in the presence of water is disclosed, the collagen having cross-linking structure. Artificial skin prepared by using this medical material as a wound-contacting layer (2) is also disclosed.

Abstract: A slurry compound prepared by a sintering powdery material and a binder is press-molded to obtain a contour for the final product applicable to a bone-implant such as hip prosthesis. The molded body is given a programmed movement of rotation and/or swinging to impart a centrifugal force to the sintering particles which direct toward the inner wall of the mold cavity. The final product obtained after sintering has a hollow interior having no communication to the outside. Imparting conditions of rotating/swinging movement may be changed or programmed in order to achieve a desired structure or constitution of the final product. By way of example, larger particles concentrate near the inner wall of the mold to provide a rough, porous surface of the body, whereas it has a dense core consisting mainly of sintered fine particles. A hip prosthesis having a ceramic-rich femoral head and a metal-rich stem may also be produced by so programming the movement imparting conditions.

Abstract: Disclosed is a cell-penetrable medical material in which cells can invade, comprising denatured collagen with helix content of 0 to 80%, and carrier substance having higher resistance to enzyme decomposition than the denatured collagen. An artificial skin in which this medical material is used as the wound contact layer, and its preferred manufacturing methods are also disclosed.