Patents by Inventor Takeo Moriya
Takeo Moriya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7138249Abstract: The screening method for a compound or a salt thereof that alters the binding property between Neuromedin U or a salt thereof and TGR-1 or a salt thereof, characterized by using Neuromedin U, a derivative thereof or a salt thereof and TGR-1 or a salt thereof, can be useful for screening a therapeutic and/or prophylactic agent for hypertension and stress-related diseases, etc. A TGR-1 antagonist can be useful as a therapeutic and/or prophylactic agent for hypertension and stress-related diseases, etc.Type: GrantFiled: February 2, 2001Date of Patent: November 21, 2006Assignee: Takeda Pharmaceutical Company LimitedInventors: Shuji Hinuma, Yasushi Shintani, Masaki Hosoya, Ryo Fujii, Takeo Moriya, Hideki Matsui, Shoichi Okubo
-
Patent number: 6949648Abstract: Novel pharmaceutical compositions for inhibiting Th2-selective immune response and pharmaceutical compositions for inhibiting cyclooxygenase comprising condensed pyrazole derivatives represented by the general formula (I): or salts thereof.Type: GrantFiled: March 27, 2001Date of Patent: September 27, 2005Assignee: Takeda Pharmaceutical Company LimitedInventors: Osamu Uchikawa, Keita Mitsui, Akiko Asakawa, Shigeru Morimoto, Masataka Yamamoto, Hiroyuki Kimura, Takeo Moriya, Masahiro Mizuno
-
Publication number: 20050053601Abstract: A novel G protein-conjugating receptor protein containing an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO.1, or its salt; a polynucleotide encoding the same; and medicinal use, etc. thereof.Type: ApplicationFiled: April 26, 2001Publication date: March 10, 2005Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Hideki Matsui
-
Publication number: 20040248321Abstract: The present invention provides a human-derived protein or a salt thereof, a DNA encoding the same, a method for determination of ligand to the protein, a screening method/kits for a compound or its salt that alters a binding property between ligand and the protein, and the like. The human-derived protein or a DNA encoding the same of the present invention can be used in (1) determination of ligand to the protein of the present invention, (2) a prophylactic/therapeutic agent for diseases associated with dysfunction of the protein of the present invention, (3) a screening of a compound (agonist, antagonist, etc.) that alters a binding property between the protein and the ligand of the present invention, and the like.Type: ApplicationFiled: May 19, 2003Publication date: December 9, 2004Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
-
Publication number: 20040152136Abstract: The screening method for a compound or a salt thereof that alters the binding property between Neuromedin U or a salt thereof and TGR-1 or a salt thereof, characterized by using Neuromedin U, a derivative thereof or a salt thereof and TGR-1 or a salt thereof, can be useful for screening a therapeutic and/or prophylactic agent for hypertension and stress-related diseases, etc. A TGR-1 antagonist can be useful as a therapeutic and/or prophylactic agent for hypertension and stress-related diseases, etc.Type: ApplicationFiled: September 23, 2002Publication date: August 5, 2004Inventors: Shuji Hinuma, Yasushi Shintani, Masaki Hosoya, Ryo Fujii, Takeo Moriya, Hideki Matsui, Shoichi Okubo
-
Publication number: 20040086505Abstract: The present invention provides a human-derived protein or a salt thereof, a DNA encoding the same, a method for determination of ligand to the protein, a screening method/kits for a compound or its salt that alters a binding property between ligand and the protein, and the like. The human-derived protein or a DNA encoding the same of the present invention can be used in (1) determination of ligand to the protein of the present invention, (2) a prophylactic/therapeutic agent for diseases associated with dysfunction of the protein of the present invention, (3) a screening of a compound (agonist, antagonist, etc.) that alters a binding property between the protein and the ligand of the present invention, and the like.Type: ApplicationFiled: January 6, 2003Publication date: May 6, 2004Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
-
Publication number: 20040038238Abstract: The present invention provides a human-derived protein or a salt thereof, a DNA encoding the same, a method for determination of ligand to the protein, a screening method/kits for a compound or its salt that alters a binding property between ligand and the protein, and the like. The human-derived protein or a DNA encoding the same of the present invention can be used in (1) determination of ligand to the protein of the present invention, (2) a prophylactic/therapeutic agent for diseases associated with dysfunction of the protein of the present invention, (3) a screening of a compound (agonist, antagonist, etc.) that alters a binding property between the protein and the ligand of the present invention, and the like.Type: ApplicationFiled: January 6, 2003Publication date: February 26, 2004Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
-
Publication number: 20040029793Abstract: The present invention provides a novel G protein-coupled receptor protein comprising the same or substantially the same amino acid sequence as that represented by SEQ ID NO: 5 or salts thereof, and a polynucleotide encoding the same. The present invention also provides a use such as pharmaceuticals, etc.Type: ApplicationFiled: May 1, 2003Publication date: February 12, 2004Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
-
Publication number: 20030187014Abstract: Novel pharmaceutical compositions for inhibiting Th2-selective immune response and pharmaceutical compositions for inhibiting cyclooxygenase comprising condensed pyrazole derivatives represented by the general formula (I): 1Type: ApplicationFiled: September 25, 2002Publication date: October 2, 2003Inventors: Osamu Uchikawa, Keita Mitsui, Akiko Asakawa, Shigeru Morimoto, Masataka Yamamoto, Hiroyuki Kimura, Takeo Moriya, Masahiro Mizuno
-
Publication number: 20030157648Abstract: The present invention aims at screening of a novel G protein-coupled receptor protein and elucidation of its function.Type: ApplicationFiled: March 11, 2003Publication date: August 21, 2003Inventors: Takeo Moriya, Takashi Ito, Ysushi Shintani, Nobuyuki Miyajima
-
Publication number: 20030153040Abstract: A novel G protein-conjugating receptor protein containing an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO.1, or its salt; a polynucleotide encoding the same; and medicinal use, etc. thereof.Type: ApplicationFiled: October 25, 2002Publication date: August 14, 2003Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Hideki Matsui
-
Patent number: 5971112Abstract: In a drum brake for a vehicle in which a pair of brake shoes 4 and 5 having an identical size are pressed against an inner face of a brake drum 1 so as to effect braking, a natural frequency of one (4) of said pair of brake shoes 4 and 5 is made different from a natural frequency of the other (5). Due to the difference in the respective natural frequencies of the right and left brake shoes 4 and 5, coupled vibrations between the brake drum 1 and the two brake shoes 4 and 5 are hard to cause, whereby it is effective in drastically reducing opportunities of generating "judder.Type: GrantFiled: July 25, 1997Date of Patent: October 26, 1999Assignee: Tokyo Buhin Kogyo Co., Ltd.Inventors: Norihisa Okada, Takeo Moriya
-
Patent number: 5932457Abstract: There is disclosed a process for producing D-pantoic acid or D-pantothenic acid utilizing the capability of the microorganism to synthesize D-pantoic acid or D-pantothenic acid. According to this process, (a) D-pantoic acid is biosynthesized from various carbon sources such as glucose to accumulate it in the culture medium, or (b) .beta.-alanine is contacted with the microorganism by, for example, adding .beta.-alanine to the culture medium, to cause condensation of the biosynthesized D-pantoic acid with .beta.-alanine to accumulate D-pantothenic acid in the medium.Type: GrantFiled: January 8, 1997Date of Patent: August 3, 1999Assignee: Takeda Chemical Industries, LtdInventors: Takeo Moriya, Yuichi Hikichi, Yumiko Moriya, Takamasa Yamaguchi
-
Patent number: 5518906Abstract: A method of producing D-pantothenic acid or a salt thereof characterized by bring a microbe belonging to the family Enterobacteriaceae having resistance to salicylic acid and capable of producing D-pantothenic acid in the presence of .beta.-alanine in contact with .beta.-alanine, preferably wherein a microbe resistant to .alpha.-ketoisovaleric acid and/or .alpha.-ketobutyric acid, and/or .alpha.-aminobutyric acid and/or .beta.-hydroxy-aspartic acid and/or O-methyl-threonine or a microbe transformed with a plasmid DNA carrying the region of a gene involved in biosynthesis of pantothenic acid or a salt thereof or a part thereof, is used, and a method of producing D-pantoic acid or a salt thereof characterized by culturing a microbe resistant to salicylic acid, .alpha.-ketoisovaleric acid and/or .alpha.-ketobutyric acid and/or .alpha.-aminobutyric acid and/or .beta.Type: GrantFiled: June 7, 1995Date of Patent: May 21, 1996Assignee: Takeda Chemical Industries, Ltd.Inventors: Yuichi Hikichi, Takeo Moriya, Hiroshi Miki, Takamasa Yamaguchi, Ikuo Nogami
-
Patent number: 4581308Abstract: The present invention relates to a photosensitive masking element for plate making including a support made of a transparent film; a metal thin film layer formed on the support; and a photosensitive masking layer formed on said metal thin film layer and strongly adhering thereto. In preparing masks for various colors, the photosensitive masking material of the present invention makes it unnecessary to fill and retouch ditches corresponding to unnecessary enclosing lines with a correction liquid, resulting in a marked improvement in the efficiency of plate making.Type: GrantFiled: August 21, 1984Date of Patent: April 8, 1986Assignee: Kimoto & Co., Ltd.Inventors: Takeo Moriya, Yamagata Toshio, Ogura Masako
-
Patent number: 4559293Abstract: The photosensitive recording material of the invention includes a substrate, an active ray-shielding layer formed on the substrate and a photosensitive composition layer formed on the actinic ray-shielding layer, wherein the binder used for the actinic ray-shielding layer, a material which is swellable or soluble in aqueous neutral salt solution and also and the binder used for the photosensitive composition layer is a material which is soluble in aqueous neutral salt solution. The product is provided a non-silver-salt type photosensitive recording material superior in both workability and stability with time.Type: GrantFiled: March 30, 1984Date of Patent: December 17, 1985Assignee: Kimoto & Co., Ltd.Inventors: Takeo Moriya, Toshio Yamagata, Yasunori Sugiyama
-
Patent number: 4374193Abstract: A positive-working photosensitive material and a process for developing the same are disclosed.The positive-working photosensitive material is obtained by forming on a base material a layer of a photosensitive composition containing (A), 100 weight parts of a resin binder including a vinylic polymer compound having phenolic hydroxyl groups and (B), 3-30 weight parts of an aromatic diazonium salt having only a single diazo group.The positive-working photosensitive material is developed by using an aqueous alkali solution.Type: GrantFiled: April 29, 1981Date of Patent: February 15, 1983Assignee: Kimoto & Co., Ltd.Inventors: Takeo Moriya, Toshio Yamagata
-
Patent number: 4296193Abstract: A photosensitive material and a process for developing the same are disclosed.The photosensitive material is obtained by forming on a base material a layer of photosensitive composition comprising (A), 100 weight parts of a water soluble resin binder containing at least 60 weight % of acrylamide-diacetoneacrylamide copolymer, the copolymerization ratio of acrylamide and diacetoneacrylamide being 8:2-5:5 and average polymerization degree being 300-1500, and (B), 5-20 weight parts of a water soluble diazonium salt.The photosensitive material is developed by using an aqueous alkali solution.Type: GrantFiled: June 20, 1980Date of Patent: October 20, 1981Assignee: Kimoto & Co., Ltd.Inventors: Takeo Moriya, Toshio Yamagata
-
Patent number: 4205989Abstract: There is disclosed a dry system image producing element comprising a substrate, a thin metal layer and a photosensitive layer. After exposing the element to light through a desired pattern, the photosensitive layer is peeled off to obtain a light barrier pattern made from the metal on the substrate corresponding to the photosensitized portion.Type: GrantFiled: August 17, 1978Date of Patent: June 3, 1980Assignee: Kimoto & Co., Ltd.Inventors: Takeo Moriya, Toshio Yamagata