Patents by Inventor Takeo Ozaki

Takeo Ozaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200305731
    Abstract: Provided is a cerebral blood flow measurement method of quantitatively measuring cerebral blood flow, the measurement method including: a tracer introducing step of introducing a tracer into a blood vessel; a light applying step of applying measurement light including an absorption wavelength of the tracer to a head; a light detecting step of detecting the measurement light propagating in the head and generating a detection signal based on light intensity of the measurement light; and a calculation step of calculating cerebral blood flow on the basis of a relative change over time ?Q of a concentration of the tracer in a brain tissue which is acquired on the basis of the detection signal and a predetermined relationship between a change over time of a concentration Pa of the tracer in an artery of the head and cerebral blood flow.
    Type: Application
    Filed: October 24, 2018
    Publication date: October 1, 2020
    Applicants: NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, HAMAMATSU PHOTONICS K.K.
    Inventors: Kenji YOSHITANI, Shinya KATO, Mariko EZAKA, Takeo OZAKI
  • Patent number: 10660551
    Abstract: A concentration measurement apparatus measures a temporal relative change amount (?cHb, ?O2Hb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (?cHb, ?O2Hb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (?cHb, ?O2Hb).
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: May 26, 2020
    Assignees: ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE, HAMAMATSU PHOTONICS K.K.
    Inventors: Yasuaki Koyama, Takeo Ozaki, Susumu Suzuki
  • Patent number: 10405783
    Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: September 10, 2019
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Takeo Ozaki, Susumu Suzuki
  • Patent number: 10370154
    Abstract: A packing bag to store a stored article Z with tight seal by a welded sheet material 1 of resin in which a separation-prepared line portion 5, separable by predetermined tensile force F by human hands to take out the stored article Z, is provided along an opening-prepared side portion 10, the sheet material 1 has a layered unit construction in which first and second welding resin layers 61A and 61B are disposed on both sides, and a barrier layer 60 is disposed on a middle position, the separation-prepared line portion 5 is composed of a half-cut first laser-worked groove 7A concaved on the first welding resin layer 61A and a half-cut second laser-worked groove 7B concaved on the second welding resin layer 61B, and, the first and second laser-worked grooves 7A and 7B are formed barely damaging the barrier layer 60.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: August 6, 2019
    Assignee: MUPACK OZAKI CO., LTD.
    Inventors: Ikuko Ozaki, Takeo Takashiro
  • Publication number: 20180020959
    Abstract: A concentration measurement apparatus measures a temporal relative change amount (?cHb, ?O2Hb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (?cHb, ?O2Hb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (?cHb, ?O2Hb).
    Type: Application
    Filed: September 29, 2017
    Publication date: January 25, 2018
    Inventors: Yasuaki KOYAMA, Takeo OZAKI, Susumu SUZUKI
  • Patent number: 9808189
    Abstract: A concentration measurement apparatus measures a temporal relative change amount (?cHb, ?O2Hb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (?cHb, ?O2Hb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (?cHb, ?O2Hb).
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: November 7, 2017
    Assignees: St. Marianna University School of Medicine, HAMAMATSU PHOTONICS K.K.
    Inventors: Yasuaki Koyama, Takeo Ozaki, Susumu Suzuki
  • Publication number: 20170258381
    Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.
    Type: Application
    Filed: June 1, 2017
    Publication date: September 14, 2017
    Inventors: Takeo OZAKI, Susumu SUZUKI
  • Patent number: 9700248
    Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.
    Type: Grant
    Filed: December 25, 2012
    Date of Patent: July 11, 2017
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Takeo Ozaki, Susumu Suzuki
  • Publication number: 20150051464
    Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, a CPU determining a temporal relative change amount of oxygenated hemoglobin concentration and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount, and a display section displaying first time series data indicating the filtering-processed relative change amount. The CPU judges whether or not chest compression is being performed. If chest compression is not performed for a predetermined time, the display section switches from displaying the first time series data to displaying second time series data indicating the relative change amount that contains frequency components less than the predetermined frequency.
    Type: Application
    Filed: December 25, 2012
    Publication date: February 19, 2015
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Takeo Ozaki, Susumu Suzuki
  • Publication number: 20150045640
    Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.
    Type: Application
    Filed: December 25, 2012
    Publication date: February 12, 2015
    Inventors: Takeo Ozaki, Susumu Suzuki
  • Publication number: 20140058233
    Abstract: A concentration measurement apparatus measures a temporal relative change amount (?cHb, ?O2Hb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (?cHb, ?O2Hb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (?cHb, ?O2Hb).
    Type: Application
    Filed: April 6, 2012
    Publication date: February 27, 2014
    Applicants: HAMAMATSU PHOTONICS K.K., ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Yasuaki Koyama, Takeo Ozaki, Susumu Suzuki
  • Patent number: 5564418
    Abstract: Perform measurement of blood flow using physiological salt solution, which is harmless to living objects, as a tracer. The head portion (4) of a subject is alternately irradiated with laser light 1, and laser light 2. The light exiting from the head portion (4) is detected and converted to an electric signal. By performing a first calculation on this electric signal, a CPU (1) outputs a signal representing the change in concentration of hemoglobin in the head (4). Further, a second calculation process is performed on the electric signal which represents changes in concentration of hemoglobin generated by injection of the physiological salt solution. At least one of the blood flow or the absolute concentration of oxyhemoglobin and deoxyhemoglobin is displayed. Because a material safe to living objects is used as the tracer, measurement of the blood flow can be safely and repeatedly performed.
    Type: Grant
    Filed: March 28, 1994
    Date of Patent: October 15, 1996
    Assignee: Hamamatsu Photonics K.K.
    Inventors: Takeo Ozaki, Susumu Suzuki
  • Patent number: 5103829
    Abstract: An examination apparatus for measuring the oxygenation in body organs by the near infrared light transmission spectrophotometry. The invention relates to an improvement of an illumination-side fixture and a detection-side fixture. In order to hold optical fibers for introducing infrared light in their natural conditions, the fixtures are equipped with respective prisms for changing light paths by prescribed angles. Also, the fixtures are equipped with respective light-emitting diodes for indicating if the examination apparatus is in its operating condition.
    Type: Grant
    Filed: May 2, 1988
    Date of Patent: April 14, 1992
    Assignee: Hamamatsu Photonics Kabushiki Kaisha
    Inventors: Susumu Suzuki, Sumio Yagi, Naotoshi Hakamata, Takeo Ozaki
  • Patent number: 5003977
    Abstract: A device for analyzing fluorescent light signals consists of memory means for storing as a reference spectrum a spectrum obtained under predetermined conditions, and extraction means for extracting a predetermined component spectrum based on the results of a conversion of the reference spectrum using a specific wavelength of a measured spectrum obtained during actual measurement and a specific wavelength of the reference spectrum. The arrangement of the invention allows the spectrum of a specific component to be extracted accurately from measured spectra.
    Type: Grant
    Filed: March 9, 1989
    Date of Patent: April 2, 1991
    Assignees: Agency of Industrial Science and Technology, Ministry of International Trade and Industry
    Inventors: Susumu Suzuki, Kazuyuki Ishida, Takeo Ozaki
  • Patent number: 4907876
    Abstract: An examination apparatus which measures the oxygenation in objects with near infrared light transmission spectrophotometry and that automatically adjusts a transmission light quantity to a magnitude suitable for detection by a photomultiplier tube. The examination apparatus comprises a ring-like ND filter whose transmission factor varies along its circumference, a filter driver for automatically setting a transmission factor of a filter, and a light source control device for automatically controlling output powers of light sources.
    Type: Grant
    Filed: May 2, 1988
    Date of Patent: March 13, 1990
    Assignee: Hamamatsu Photonics Kabushiki Kaisha
    Inventors: Susumu Suzuki, Sumio Yagi, Naotoshi Hakamata, Takeo Ozaki
  • Patent number: 4908762
    Abstract: An examination apparatus measures the oxygenation in body organs by the near infrared light transmission spectrophotometry. To inspect the examination apparatus itself before the oxygenation measurement, an illumination-side fixture and a detection-side fixture have such structures that these fixtures can be assembled together in such a manner that near infrared light is directly made incident on the detection-side fixture from the illumination-side fixture. In the midst of the measurement, the examination apparatus is regularly inspected and a photomultiplier tube can be separately inspected by employing a separate light source for inspection.
    Type: Grant
    Filed: May 2, 1988
    Date of Patent: March 13, 1990
    Assignee: Hamamatsu Photonics Kabushiki Kaisha
    Inventors: Susumu Suzuki, Sumio Yagi, Naotoshi Hakamata, Takeo Ozaki
  • Patent number: 4901238
    Abstract: An examination apparatus measures the oxygenation of body organs by using the near infrared transmission spectrophotometry. To assure the measurement reliability and the object person's safety, the examination apparatus monitors the variation of the fitting position of an illumination-side fixture by detecting the reflection light quantity from the measuring object.
    Type: Grant
    Filed: May 2, 1988
    Date of Patent: February 13, 1990
    Assignee: Hamamatsu Photonics Kabushiki Kaisha
    Inventors: Susumu Suzuki, Sumio Yagi, Naotoshi Hakamata, Takeo Ozaki
  • Patent number: 3959449
    Abstract: A method of recovering in highly pure states heavy metals such as cobalt, manganese, etc.
    Type: Grant
    Filed: April 1, 1974
    Date of Patent: May 25, 1976
    Assignee: Matsuyama Petrochemicals Inc.
    Inventors: Motoo Shigeyasu, Takeo Ozaki, Nobuo Kusano