Patents by Inventor Takeo Ozaki
Takeo Ozaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210401335Abstract: A concentration measurement apparatus includes a light input unit for inputting measurement light to a measurement target portion, a light detection unit for detecting the measurement light propagated inside the measurement target portion, and generating a detection signal according to an intensity of the measurement light, and a calculation unit for obtaining hemoglobin-related information based on the detection signal. The calculation unit performs filter processing of extracting a component derived from respiration among frequency components included in the detection signal, the hemoglobin-related information, or a numerical value appearing in a calculation process of the hemoglobin-related information for obtaining the hemoglobin-related information in a vein of the measurement target portion.Type: ApplicationFiled: October 30, 2019Publication date: December 30, 2021Applicant: HAMAMATSU PHOTONICS K.K.Inventors: Tsuyoshi KAMADA, Takeo OZAKI, Wataru KAMO
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Publication number: 20200305731Abstract: Provided is a cerebral blood flow measurement method of quantitatively measuring cerebral blood flow, the measurement method including: a tracer introducing step of introducing a tracer into a blood vessel; a light applying step of applying measurement light including an absorption wavelength of the tracer to a head; a light detecting step of detecting the measurement light propagating in the head and generating a detection signal based on light intensity of the measurement light; and a calculation step of calculating cerebral blood flow on the basis of a relative change over time ?Q of a concentration of the tracer in a brain tissue which is acquired on the basis of the detection signal and a predetermined relationship between a change over time of a concentration Pa of the tracer in an artery of the head and cerebral blood flow.Type: ApplicationFiled: October 24, 2018Publication date: October 1, 2020Applicants: NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, HAMAMATSU PHOTONICS K.K.Inventors: Kenji YOSHITANI, Shinya KATO, Mariko EZAKA, Takeo OZAKI
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Patent number: 10660551Abstract: A concentration measurement apparatus measures a temporal relative change amount (?cHb, ?O2Hb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (?cHb, ?O2Hb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (?cHb, ?O2Hb).Type: GrantFiled: September 29, 2017Date of Patent: May 26, 2020Assignees: ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE, HAMAMATSU PHOTONICS K.K.Inventors: Yasuaki Koyama, Takeo Ozaki, Susumu Suzuki
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Patent number: 10405783Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.Type: GrantFiled: June 1, 2017Date of Patent: September 10, 2019Assignee: HAMAMATSU PHOTONICS K.K.Inventors: Takeo Ozaki, Susumu Suzuki
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Publication number: 20180020959Abstract: A concentration measurement apparatus measures a temporal relative change amount (?cHb, ?O2Hb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (?cHb, ?O2Hb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (?cHb, ?O2Hb).Type: ApplicationFiled: September 29, 2017Publication date: January 25, 2018Inventors: Yasuaki KOYAMA, Takeo OZAKI, Susumu SUZUKI
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Patent number: 9808189Abstract: A concentration measurement apparatus measures a temporal relative change amount (?cHb, ?O2Hb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (?cHb, ?O2Hb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (?cHb, ?O2Hb).Type: GrantFiled: April 6, 2012Date of Patent: November 7, 2017Assignees: St. Marianna University School of Medicine, HAMAMATSU PHOTONICS K.K.Inventors: Yasuaki Koyama, Takeo Ozaki, Susumu Suzuki
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Publication number: 20170258381Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.Type: ApplicationFiled: June 1, 2017Publication date: September 14, 2017Inventors: Takeo OZAKI, Susumu SUZUKI
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Patent number: 9700248Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.Type: GrantFiled: December 25, 2012Date of Patent: July 11, 2017Assignee: HAMAMATSU PHOTONICS K.K.Inventors: Takeo Ozaki, Susumu Suzuki
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Publication number: 20150051464Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, a CPU determining a temporal relative change amount of oxygenated hemoglobin concentration and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount, and a display section displaying first time series data indicating the filtering-processed relative change amount. The CPU judges whether or not chest compression is being performed. If chest compression is not performed for a predetermined time, the display section switches from displaying the first time series data to displaying second time series data indicating the relative change amount that contains frequency components less than the predetermined frequency.Type: ApplicationFiled: December 25, 2012Publication date: February 19, 2015Applicant: HAMAMATSU PHOTONICS K.K.Inventors: Takeo Ozaki, Susumu Suzuki
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Publication number: 20150045640Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.Type: ApplicationFiled: December 25, 2012Publication date: February 12, 2015Inventors: Takeo Ozaki, Susumu Suzuki
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Publication number: 20140058233Abstract: A concentration measurement apparatus measures a temporal relative change amount (?cHb, ?O2Hb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (?cHb, ?O2Hb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (?cHb, ?O2Hb).Type: ApplicationFiled: April 6, 2012Publication date: February 27, 2014Applicants: HAMAMATSU PHOTONICS K.K., ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINEInventors: Yasuaki Koyama, Takeo Ozaki, Susumu Suzuki
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Patent number: 5564418Abstract: Perform measurement of blood flow using physiological salt solution, which is harmless to living objects, as a tracer. The head portion (4) of a subject is alternately irradiated with laser light 1, and laser light 2. The light exiting from the head portion (4) is detected and converted to an electric signal. By performing a first calculation on this electric signal, a CPU (1) outputs a signal representing the change in concentration of hemoglobin in the head (4). Further, a second calculation process is performed on the electric signal which represents changes in concentration of hemoglobin generated by injection of the physiological salt solution. At least one of the blood flow or the absolute concentration of oxyhemoglobin and deoxyhemoglobin is displayed. Because a material safe to living objects is used as the tracer, measurement of the blood flow can be safely and repeatedly performed.Type: GrantFiled: March 28, 1994Date of Patent: October 15, 1996Assignee: Hamamatsu Photonics K.K.Inventors: Takeo Ozaki, Susumu Suzuki
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Patent number: 5103829Abstract: An examination apparatus for measuring the oxygenation in body organs by the near infrared light transmission spectrophotometry. The invention relates to an improvement of an illumination-side fixture and a detection-side fixture. In order to hold optical fibers for introducing infrared light in their natural conditions, the fixtures are equipped with respective prisms for changing light paths by prescribed angles. Also, the fixtures are equipped with respective light-emitting diodes for indicating if the examination apparatus is in its operating condition.Type: GrantFiled: May 2, 1988Date of Patent: April 14, 1992Assignee: Hamamatsu Photonics Kabushiki KaishaInventors: Susumu Suzuki, Sumio Yagi, Naotoshi Hakamata, Takeo Ozaki
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Patent number: 5003977Abstract: A device for analyzing fluorescent light signals consists of memory means for storing as a reference spectrum a spectrum obtained under predetermined conditions, and extraction means for extracting a predetermined component spectrum based on the results of a conversion of the reference spectrum using a specific wavelength of a measured spectrum obtained during actual measurement and a specific wavelength of the reference spectrum. The arrangement of the invention allows the spectrum of a specific component to be extracted accurately from measured spectra.Type: GrantFiled: March 9, 1989Date of Patent: April 2, 1991Assignees: Agency of Industrial Science and Technology, Ministry of International Trade and IndustryInventors: Susumu Suzuki, Kazuyuki Ishida, Takeo Ozaki
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Patent number: 4907876Abstract: An examination apparatus which measures the oxygenation in objects with near infrared light transmission spectrophotometry and that automatically adjusts a transmission light quantity to a magnitude suitable for detection by a photomultiplier tube. The examination apparatus comprises a ring-like ND filter whose transmission factor varies along its circumference, a filter driver for automatically setting a transmission factor of a filter, and a light source control device for automatically controlling output powers of light sources.Type: GrantFiled: May 2, 1988Date of Patent: March 13, 1990Assignee: Hamamatsu Photonics Kabushiki KaishaInventors: Susumu Suzuki, Sumio Yagi, Naotoshi Hakamata, Takeo Ozaki
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Patent number: 4908762Abstract: An examination apparatus measures the oxygenation in body organs by the near infrared light transmission spectrophotometry. To inspect the examination apparatus itself before the oxygenation measurement, an illumination-side fixture and a detection-side fixture have such structures that these fixtures can be assembled together in such a manner that near infrared light is directly made incident on the detection-side fixture from the illumination-side fixture. In the midst of the measurement, the examination apparatus is regularly inspected and a photomultiplier tube can be separately inspected by employing a separate light source for inspection.Type: GrantFiled: May 2, 1988Date of Patent: March 13, 1990Assignee: Hamamatsu Photonics Kabushiki KaishaInventors: Susumu Suzuki, Sumio Yagi, Naotoshi Hakamata, Takeo Ozaki
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Patent number: 4901238Abstract: An examination apparatus measures the oxygenation of body organs by using the near infrared transmission spectrophotometry. To assure the measurement reliability and the object person's safety, the examination apparatus monitors the variation of the fitting position of an illumination-side fixture by detecting the reflection light quantity from the measuring object.Type: GrantFiled: May 2, 1988Date of Patent: February 13, 1990Assignee: Hamamatsu Photonics Kabushiki KaishaInventors: Susumu Suzuki, Sumio Yagi, Naotoshi Hakamata, Takeo Ozaki
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Patent number: 3959449Abstract: A method of recovering in highly pure states heavy metals such as cobalt, manganese, etc.Type: GrantFiled: April 1, 1974Date of Patent: May 25, 1976Assignee: Matsuyama Petrochemicals Inc.Inventors: Motoo Shigeyasu, Takeo Ozaki, Nobuo Kusano