Abstract: Disclosed are a method for potentiating a sirtuin gene in a living body, provided to the living body as a pharmaceutical product, a cosmetic product, or a food product including a sirtuin gene potentiator. The sirtuin gene potentiator of the present invention contains a given polyphenol and/or terpenoid as an active component. The polyphenol and/or the terpenoid can be contained in the form of a plant such as pomegranate or a plant extract thereof. The sirtuin gene potentiator of the present invention is available from a familiar material to avoid concerns such as side effects on the human body in advance. Such a sirtuin gene potentiator is useful as a novel material in the fields of pharmaceutical products, cosmetic products, and food products.

Abstract: Disclosed are a sirtuin gene potentiator, and a pharmaceutical product, a cosmetic product, and a food product using the same. The sirtuin gene potentiator of the present invention contains a given polyphenol and/or terpenoid as an active component. The polyphenol and/or the terpenoid can be contained in the form of a plant such as pomegranate or a plant extract thereof. The sirtuin gene potentiator of the present invention is available from a familiar material to avoid concerns such as side effects on the human body in advance. Such a sirtuin gene potentiator is useful as a novel material in the fields of pharmaceutical products, cosmetic products, and food products.

Abstract: The yield of active polysaccharides contained in Agaricus blazei, such as ?-glucan, can be improved, by decomposing and treating the mycelium or fruit body of Agaricus blazei or a liquid waste of the culture of the mycelium with an enzymatic agent principally comprising hemicellulase. By increasing the concentrations of the active polysaccharides, furthermore, the digestion and absorption of the biologically active substance of the present invention after the incorporation thereof into bodies is prominently elevated, so that the active substance can exert excellent immune activation effect on cancers and other adult diseases.

Abstract: The yield of active polysaccharides contained in Agaricus blazei, such as &bgr;-glucan, can be improved, by decomposing and treating the mycelium or fruit body of Agaricus blazei or a liquid waste of the culture of the mycelium with an enzymatic agent principally comprising hemicellulase.

Abstract: The yield of active polysaccharides contained in Agaricus blazei, such as &bgr;-glucan, can be improved, by decomposing and treating the mycelium or fruit body of Agaricus blazei or a liquid waste of the culture of the mycelium with an enzymatic agent principally comprising hemicellulase. By increasing the concentrations of the active of the biologically active substance of the present invention after the incorporation thereof into bodies is prominently elevated, so that the active substance can exert excellent immune activation effect on cancers and other adult diseases.