Patents by Inventor Takeru Yoshimura

Takeru Yoshimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MetAP-2 inhibitor polymersomes for therapeutic administration
    Patent number: 9782489
    Abstract: The present invention provides methods to treating inflammation related disease and disorders such as an autoimmune disease and autoimmune related uveitis by administering compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. The composition comprises a formulation of a fumagillol derivative that retains anti-inflammation activity and is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: October 10, 2017
    Assignee: Children's Medical Center Corporation
    Inventors: Ofra Benny-Ratsaby, Robert D'Amato, Takeru Yoshimura
  • METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION
    Publication number: 20160361428
    Abstract: The present invention provides methods to treating inflammation related disease and disorders such as an autoimmune disease and autoimmune related uveitis by administering compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. The composition comprises a formulation of a fumagillol derivative that retains anti-inflammation activity and is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety.
    Type: Application
    Filed: August 26, 2016
    Publication date: December 15, 2016
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Ofra Benny-Ratsaby, Robert D'Amato, Takeru Yoshimura
  • MetAP-2 inhibitor polymersomes for therapeutic administration
    Patent number: 9446140
    Abstract: The present invention provides methods to treating inflammation related disease and disorders such as an autoimmune disease and autoimmune related uveitis by administering compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. The composition comprises a formulation of a fumagillol derivative that retains anti-inflammation activity and is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: September 20, 2016
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Ofra Benny-Ratsaby, Robert D'Amato, Takeru Yoshimura
  • METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION
    Publication number: 20140301969
    Abstract: The present invention provides methods to treating inflammation related disease and disorders such as an autoimmune disease and autoimmune related uveitis by administering compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. The composition comprises a formulation of a fumagillol derivative that retains anti-inflammation activity and is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety.
    Type: Application
    Filed: June 24, 2014
    Publication date: October 9, 2014
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Ofra Benny-Ratsaby, Robert D'Amato, Takeru Yoshimura
  • MetAP-2 inhibitor polymersomes for therapeutic administration
    Patent number: 8790634
    Abstract: The present invention provides methods to treating inflammation related disease and disorders such as an autoimmune disease and autoimmune related uveitis by administering compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. The composition comprises a formulation of a fumagillol derivative that retains anti-inflammation activity and is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: July 29, 2014
    Assignee: Children's Medical Center Corporation
    Inventors: Ofra Benny-Ratsaby, Robert D'Amato, Takeru Yoshimura
  • METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION
    Publication number: 20100158855
    Abstract: The present invention provides methods to treating inflammation related disease and disorders such as an autoimmune disease and autoimmune related uveitis by administering compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. The composition comprises a formulation of a fumagillol derivative that retains anti-inflammation activity and is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety.
    Type: Application
    Filed: December 28, 2009
    Publication date: June 24, 2010
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Ofra Benny-Ratsaby, Robert D'Amato, Takeru Yoshimura