Patents by Inventor Takeshi Baba

Takeshi Baba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240158482
    Abstract: An objective of the present invention is to provide methods for promoting antigen uptake into cells by antigen-binding molecules, methods for increasing the number of times of antigen binding by one antigen-binding molecule, methods for promoting reduction of the antigen concentration in plasma by administering antigen-binding molecules, and methods for improving the plasma retention of an antigen-binding molecule, as well as antigen-binding molecules that allow enhanced antigen uptake into cells, antigen-binding molecules having an increased number of times of antigen binding, antigen-binding molecules that can promote reduction of the antigen concentration in plasma when administered, antigen-binding molecules with improved plasma retention, pharmaceutical compositions comprising the above antigen-binding molecules, and methods for producing them. The present inventors revealed that the above objective can be achieved by using antigen-binding molecules that show calcium-dependent antigen-antibody reaction.
    Type: Application
    Filed: December 20, 2023
    Publication date: May 16, 2024
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Tomoyuki Igawa, Shinya Ishii, Miho Funaki, Naoka Hironiwa, Atsuhiko Maeda, Junichi Nezu, Yoshinao Ruike, Takeshi Baba, Shun Shimizu
  • Patent number: 11891434
    Abstract: An objective of the present invention is to provide methods for promoting antigen uptake into cells by antigen-binding molecules, methods for increasing the number of times of antigen binding by one antigen-binding molecule, methods for promoting reduction of the antigen concentration in plasma by administering antigen-binding molecules, and methods for improving the plasma retention of an antigen-binding molecule, as well as antigen-binding molecules that allow enhanced antigen uptake into cells, antigen-binding molecules having an increased number of times of antigen binding, antigen-binding molecules that can promote reduction of the antigen concentration in plasma when administered, antigen-binding molecules with improved plasma retention, pharmaceutical compositions comprising the above antigen-binding molecules, and methods for producing them. The present inventors revealed that the above objective can be achieved by using antigen-binding molecules that show calcium-dependent antigen-antibody reaction.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: February 6, 2024
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Tomoyuki Igawa, Shinya Ishii, Miho Funaki, Naoka Hironiwa, Atsuhiko Maeda, Junichi Nezu, Yoshinao Ruike, Takeshi Baba, Shun Shimizu
  • Patent number: 11827699
    Abstract: The present inventors newly discovered that even if an antigen-binding molecule inhibits in vitro some of the physiological activities of an antigen having two or more physiological activities without inhibiting the remaining physiological activities, the molecule can promote elimination of the antigen from blood (from serum or plasma) and as a result reduce the physiological activities in vivo, when the antigen-binding molecule is conferred with the properties: (i) of binding to human FcRn under an acidic pH range condition; (ii) of binding under a neutral pH range condition to human Fc receptor stronger than native human IgG, and (iii) that its antigen-binding activity alters according to the ion concentration.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: November 28, 2023
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Tomoyuki Igawa, Atsuhiko Maeda, Shigero Tamba, Takehisa Kitazawa, Takeshi Baba, Yoshinao Ruike, Junichi Nezu
  • Patent number: 11726259
    Abstract: An optical circuit element formed on a substrate, the optical circuit element includes a first waveguide and a second waveguide, the second waveguide having a shape in a width direction, the shape being asymmetrical to the first waveguide. The first waveguide includes a first segment and a second segment, the first segment having a width that changes along a light propagation direction, the second segment continuous with the first segment. The second waveguide includes a coupled waveguide adjacent to the second segment of the first waveguide. At least one of the second segment and the coupled waveguide has a shape with a width that changes along the light propagation direction.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: August 15, 2023
    Assignee: FUJITSU OPTICAL COMPONENTS LIMITED
    Inventor: Takeshi Baba
  • Publication number: 20230187585
    Abstract: A method for manufacturing a light-emitting element includes: providing a structure body including: a semiconductor structure body having a first surface, a second surface located on a side opposite to the first surface, and a lateral surface that connects the first surface and the second surface, a first insulating film covering the lateral surface of the semiconductor structure body, a second insulation film covering the first surface of the semiconductor structure body and an upper surface of the first insulating film on a first surface side, and a substrate facing the second surface of the semiconductor structure body; forming a mask on a part of the second insulating film located above the first surface of the semiconductor structure body; and removing a part of the second insulating film located around the mask in a top view and exposed from the mask.
    Type: Application
    Filed: December 2, 2022
    Publication date: June 15, 2023
    Applicant: NICHIA CORPORATION
    Inventors: Hirofumi KAWAGUCHI, Takeshi BABA, Taku YUASA, Kazuki KUMEGAWA
  • Patent number: 11608041
    Abstract: A braking control system includes obstacle detection means for detecting an obstacle ahead of a vehicle, first collision determination means for determining whether the vehicle would collide with the obstacle ahead of the vehicle, following vehicle detection means for detecting a following vehicle traveling behind the vehicle, information acquisition means for acquiring a maximum deceleration set in the following vehicle, second collision determination means for determining whether the following vehicle would collide with the vehicle based on the maximum deceleration, and braking control means for controlling braking means of the vehicle so that an absolute value of a deceleration of the vehicle does not exceed an absolute value of the maximum deceleration of the following vehicle when the first collision determination means determines that the vehicle would collide with the obstacle and the second collision determination means determines that the following vehicle would collide with the vehicle.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: March 21, 2023
    Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventor: Takeshi Baba
  • Patent number: 11576969
    Abstract: Provided is a novel anti-Plexin-A1 agonist antibody that promotes dendritic cell contraction. Also provided is a pharmaceutical composition comprising such an antibody and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: February 14, 2023
    Assignees: Osaka University, Chugai Seiyaku Kabushiki Kaisha
    Inventors: Atsushi Kumanogoh, Ryusuke Omiya, Hiroyuki Tsunoda, Takeshi Baba, Sachiyo Suzuki, Yuri Teranishi
  • Publication number: 20230024097
    Abstract: A driving support system includes: an information acquisition unit configured to acquire traveling characteristic information on a vehicle; a storage unit in which a dynamic map is stored, the dynamic map being a map in which static base map information, dynamic environmental information, and the traveling characteristic information acquired by the information acquisition unit are associated with each other; a collision determination unit configured to determine whether or not there is a possibility that the vehicle has a collision, based on the dynamic map stored in the storage unit; and a control unit configured to, in a case where the collision determination unit determines that there is a possibility that the vehicle has a collision, control the vehicle such that the vehicle avoids the collision.
    Type: Application
    Filed: July 20, 2022
    Publication date: January 26, 2023
    Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventor: Takeshi BABA
  • Publication number: 20220390444
    Abstract: A biochip is capable of highly sensitively detecting a measurement target substance. The biochip includes a selective-binding substance capable of selectively binding to the measurement target substance, the selective-binding substance being immobilized on a surface of a substrate through a polymer containing a unit represented by Formula (Ia) or (Ib): wherein, R1 represents C1-C4 alkylene; R2 represents R3, OR4, or NHR5; R3 and R5 each independently represent a hydrogen atom or C1-C4 alkyl; R4 represents C1-C4 alkyl; R6 represents C1-C2 alkylene; and R7 and R8 each independently represent a hydrogen atom or C1-C4 alkyl.
    Type: Application
    Filed: October 29, 2020
    Publication date: December 8, 2022
    Inventors: Sho Wakayama, Yoichiro Koshi, Takeshi Baba, Tomonori Kawakami, Masateru Ito
  • Publication number: 20220267452
    Abstract: The present disclosure provides antibodies capable of distinguishing between wild-type FGFR3 and FGFR3 S249C mutants. Using these antibodies, antigen-binding molecules capable of selectively damaging tumor cells expressing an FGFR3 S249C mutant were constructed.
    Type: Application
    Filed: July 10, 2020
    Publication date: August 25, 2022
    Inventors: Shogo KAMIKAWAJI, Takeshi BABA, Yuji SANO, Yoshito NAKANISHI
  • Patent number: 11402581
    Abstract: A mode converter for converting mode of propagating light is provided. The mode converter includes: a mode order conversion unit that includes an input-side first rib unit, an output-side first rib unit that extends along the input-side first rib unit, and a first slab unit arranged between the input-side first rib unit and the output-side first rib unit; and a rib channel conversion unit that includes an output-side second rib unit that is in contact with the output-side first rib unit, a second slab unit that is in contact with the first slab unit and a side surface of the output-side second rib unit, and a third slab unit that is in contact with another side surface of the output-side second rib unit.
    Type: Grant
    Filed: April 27, 2021
    Date of Patent: August 2, 2022
    Assignee: FUJITSU OPTICAL COMPONENTS LIMITED
    Inventor: Takeshi Baba
  • Patent number: 11359175
    Abstract: In an aspect, the present invention provides a structure, a structure-manufacturing method, a cell-sorting method, or the like. In an aspect, a structure (1) of the present invention is a structure including a first substrate (10) and a second substrate (20) disposed to face one side of the first substrate (10), in which the first substrate (10) has a plurality of depressions (11) which are open to the other side of the first substrate and each of which has a size that enables each of the depressions to capture one unit of a cell, at least some of the depressions (11) have communication holes (12) which communicate with one side and the other side of the first substrate and each of which has a size that enables secretions secreted from the cell to move through the communication holes, the second substrate (20) can include accumulation portions (13) in which the secretions moving through the communication holes (12) are accumulated, and the accumulation portions (13) can correspond to the depressions (11).
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: June 14, 2022
    Assignees: TOKYO OHKA KOGYO CO., LTD., CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Takashi Ohsaka, Yasuo Suzuki, Toshiyuki Ogata, Takuya Noguchi, Noriyuki Takahashi, Takeshi Baba, Hiroyuki Tsunoda
  • Publication number: 20220177509
    Abstract: Provided is a method for producing a compound represented by formula (III) from a compound represented by formula (I) as a starting material.
    Type: Application
    Filed: March 31, 2020
    Publication date: June 9, 2022
    Applicants: NIPPON SHOKUBAI CO., LTD., OSAKA UNIVERSITY
    Inventors: Takeshi BABA, Hiroshi OKAMOTO, Yumi NOMURA, Satoshi OBIKA, Takao YAMAGUCHI
  • Publication number: 20220032888
    Abstract: A braking control system includes obstacle detection means for detecting an obstacle ahead of a vehicle, first collision determination means for determining whether the vehicle would collide with the obstacle ahead of the vehicle, following vehicle detection means for detecting a following vehicle traveling behind the vehicle, information acquisition means for acquiring a maximum deceleration set in the following vehicle, second collision determination means for determining whether the following vehicle would collide with the vehicle based on the maximum deceleration, and braking control means for controlling braking means of the vehicle so that an absolute value of a deceleration of the vehicle does not exceed an absolute value of the maximum deceleration of the following vehicle when the first collision determination means determines that the vehicle would collide with the obstacle and the second collision determination means determines that the following vehicle would collide with the vehicle.
    Type: Application
    Filed: July 22, 2021
    Publication date: February 3, 2022
    Applicant: Toyota Jidosha Kabushiki Kaisha
    Inventor: Takeshi Baba
  • Publication number: 20210382233
    Abstract: A mode converter for converting mode of propagating light is provided. The mode converter includes: a mode order conversion unit that includes an input-side first rib unit, an output-side first rib unit that extends along the input-side first rib unit, and a first slab unit arranged between the input-side first rib unit and the output-side first rib unit; and a rib channel conversion unit that includes an output-side second rib unit that is in contact with the output-side first rib unit, a second slab unit that is in contact with the first slab unit and a side surface of the output-side second rib unit, and a third slab unit that is in contact with another side surface of the output-side second rib unit.
    Type: Application
    Filed: April 27, 2021
    Publication date: December 9, 2021
    Applicant: Fujitsu Optical Components Limited
    Inventor: Takeshi BABA
  • Publication number: 20210239905
    Abstract: An optical circuit element formed on a substrate, the optical circuit element includes a first waveguide and a second waveguide, the second waveguide having a shape in a width direction, the shape being asymmetrical to the first waveguide. The first waveguide includes a first segment and a second segment, the first segment having a width that changes along a light propagation direction, the second segment continuous with the first segment. The second waveguide includes a coupled waveguide adjacent to the second segment of the first waveguide. At least one of the second segment and the coupled waveguide has a shape with a width that changes along the light propagation direction.
    Type: Application
    Filed: February 1, 2021
    Publication date: August 5, 2021
    Applicant: FUJITSU LIMITED
    Inventor: Takeshi Baba
  • Publication number: 20200369784
    Abstract: An objective of the invention is to provide an antibody, a composition for use in detecting or capturing a polypeptide in a sample, and a method for detecting or capturing a polypeptide in sample. The disclosure provides an antibody, a composition for use in detecting or capturing a polypeptide in a sample, and a method for detecting or capturing a polypeptide in sample.
    Type: Application
    Filed: December 7, 2018
    Publication date: November 26, 2020
    Inventors: Noriyuki TAKAHASHI, Tomoyuki IGAWA, Takeshi BABA
  • Publication number: 20200276302
    Abstract: Provided is a novel anti-Plexin-A1 agonist antibody that promotes dendritic cell contraction. Also provided is a pharmaceutical composition comprising such an antibody and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: May 8, 2020
    Publication date: September 3, 2020
    Inventors: Atsushi Kumanogoh, Ryusuke Omiya, Hiroyuki Tsunoda, Takeshi Baba, Sachiyo Suzuki, Yuri Teranishi
  • Patent number: 10688178
    Abstract: Provided is a novel anti-Plexin-A1 agonist antibody that promotes dendritic cell contraction. Also provided is a pharmaceutical composition comprising such an antibody and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: June 23, 2020
    Assignees: Osaka University, Chugai Seiyaku Kabushiki Kaisha
    Inventors: Atsushi Kumanogoh, Ryusuke Omiya, Hiroyuki Tsunoda, Takeshi Baba, Sachiyo Suzuki, Yuri Teranishi
  • Publication number: 20190292288
    Abstract: A copolymer is excellent in water permeability, suppression of platelet adhesion, and suppression of protein adhesion, and a separation membrane, a medical device, and a separation membrane module for medical use using the copolymer. The copolymer includes monomer units derived from two or more types of monomers, wherein the hydration energy density of the copolymer is 158.992 to 209.200 kJ·mol?1·nm?3, the monomer unit with the highest hydration energy density in the monomer units is a monomer unit not containing a hydroxy group, the volume fraction of the monomer unit with the highest hydration energy density in the monomer units is 35 to 90%, and the difference in hydration energy density is 71.128 to 418.400 kJ·mol?1·nm?3.
    Type: Application
    Filed: August 4, 2017
    Publication date: September 26, 2019
    Applicant: Toray Industries, Inc.
    Inventors: Takeshi BABA, Tomonori KAWAKAMI, Suguru USHIRO, Yoshiyuki UENO