Abstract: A cyclic diamine compound of formula (1): wherein R1 and R2 are individually a hydrogen atom or a methoxy group, provided R1 is a methoxy group when R2 is a hydrogen atom, or a hydrogen atom when R2 is a methoxy group; A is an oxygen atom, a sulfur atom, CH?CH, CH?N or NR3, in which R3 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group; B is a nitrogen atom, CH or CR4, in which R4 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group; m is 1 or 2; and n is a number of 1 to 5, an acid-addition salt thereof, or a hydrate thereof. The compound has inhibitory effects on cell adhesion and is useful for treatment of allergy, asthma, rheumatism, arteriosclerosis, and inflammation.

Abstract: A computer-aided diagnostic method and system provide image annotation information that can include an assessment of the probability, likelihood or predictive value of detected or identified suspected abnormalities as an additional aid to the radiologist. More specifically, probability values, in numerical form and/or analog form, are added to the locational markers of the detected and suspected abnormalities. The task of a physician using such a system as disclosed is believed to be made easier by displaying markers representing different regions of interest.

Abstract: In a magnetic disk drive, a writing element and its surrounding area thermally expand due to the heat generated by a write head coil. The transient phenomenon of such thermal expansion may invoke the transient phenomenon of inadequate writing capacity, thereby causing a writing error at an early stage of a write operation. Control is provided which increases/decreases either or both the write current to be applied to a write head and the amount of its overshoot on an individual sector basis during a writing sequence.

Abstract: For use as a wet strength agent, a water-soluble blocked urethane prepolymer having a hydrophilic group and a blocked isocyanate group is combined with a cationic charge-adjusting agent. The adsorption and retention of the water-soluble blocked urethane prepolymer to cellulosic fiber are promoted by virtue of the cationic charge adjusting agent when the wet strength agent is added to a paper-making stock.

Abstract: In order to rapidly control the gains of a plurality of variable gain amplifiers VGAs, each of gain control circuits is configured to determine a gain to be set therein, based on gain control information received from other gain control circuits existing in its preceding stage or stages and the signal level detected by a level detector circuit connected thereto. By carrying out such gain control, a total application gain is stabilized more quickly by gain control. Therefore, even in receiving systems that the preparation period for reception is very short, desired gain control is achieved within this period and stable data reception can be performed.

Abstract: Abstract The present invention is directed to a method for treating cancer, a method for inhibiting histone deacetylase, and a method for facilitating gene therapy, comprising administering an effective amount of a cyclic amine compound represented by the following formula (1):(wherein R1, R2, and R3 each independently represent a hydrogen atom, a halogen atom, a hydroxy group, an alkyl group, a halogen-substituted alkyl group, an alkoxy group, an alkylthio group, a carboxyl group, an alkoxycarbonyl group, or an alkanoyl group; W1 and W2, which are identical to or different from each other, represent N or CH; X represents O, NR4, CONR4, or NR4CO; R4 represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heteroaryl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted heteroaralkyl group; and l, m, and n each represent a number of 0 or 1), a salt thereof, or a hydrate thereof.

Abstract: A design support apparatus includes a unit that inputs a user net list created by using hard macro cells excluding test circuits, and a unit that arranges hard macro cells using a frame into which hard macro cells, where timing-converged physical information includes test terminals, and test circuits are embedded as arrangement/wiring information. Moreover, includes a unit that arranges and wires the test circuits using the arrangement/wiring information of the test circuit embedded into the frame, a unit that recognizes arrangement/wiring information where the arrangement/wiring information of the test circuits is removed from arrangement/wiring information obtained by wiring, and a unit outputs a net list of a logic structure.

Abstract: A computer-aided diagnostic method and system provide image annotation information that can include an assessment of the probability, likelihood or predictive value of detected or identified suspected abnormalities as an additional aid to the radiologist. More specifically, probability values, in numerical form and/or analog form, are added to the locational markers of the detected and suspected abnormalities. The task of a physician using such a system as disclosed is believed to be made easier by displaying markers representing different regions of interest.

Abstract: A cyclic amine compound represented by the following general formula (1): wherein, R1, R2 and R3 each independently represent a hydrogen atom or an alkoxy group; W1 and W2 each independently represent N or CH; X represents O, NR4, CONR4 or NR4CO; R4 represents a hydrogen atom, or an alkyl, aryl, heteroaryl, aralkyl, or heteroaralkyl group; and l, m and n each represents a number of 0 or 1, a salt thereof and a hydrate thereof are provided. These compounds have inhibitory effects on both cell adhesion and cell infiltration and are useful as anti-asthmatic agents, anti-allergic agents, anti-rheumatic agents, anti-arteriosclerotic agents, anti-inflammatory agents, anti-Sjogren's syndrome agents or the like.

Abstract: A medical needle device includes a winged shield (4) having a substantially cylindrical shaped shield cylinder (4a) and wings (5, 6) connected to the front end side thereof, a needle base (2) inserted in the shield cylinder (4a), and a needle (1). The wings have wing projections (7, 8) and the shield cylinder has through holes (9, 10) on the wall thereof. By overlaying the wings along the side surface of the shield cylinder, each of the wing projections can be inserted into the inner cavity of the shield cylinder via the through hole. Thereby, without requiring a special operation in the sticking operation, each of the wing projections can prevent the needle base from moving in the axial direction and can hold the needle base in the shield cylinder reliably in a state in which the needle protrudes from the front end of the shield cylinder by a predetermined length.

Abstract: In order to rapidly control the gains of a plurality of variable gain amplifiers VGAs, each of gain control circuits is configured to determine a gain to be set therein, based on gain control information received from other gain control circuits existing in its preceding stage or stages and the signal level detected by a level detector circuit connected thereto. By carrying out such gain control, a total application gain is stabilized more quickly by gain control. Therefore, even in receiving systems that the preparation period for reception is very short, desired gain control is achieved within this period and stable data reception can be performed.

Abstract: In a magnetic disk drive, a writing element and its surrounding area thermally expand due to the heat generated by a write head coil. The transient phenomenon of such thermal expansion may invoke the transient phenomenon of inadequate writing capacity, thereby causing a writing error at an early stage of a write operation. Control is provided which increases/decreases either or both the write current to be applied to a write head and the amount of its overshoot on an individual sector basis during a writing sequence.

Abstract: The position information of the magnetic head is generated also from the data area to improve the positioning accuracy. The magnetic disk drive has a function of oscillating the magnetic head in the radial direction in the data area at a specific frequency and a function of detecting a read signal during the execution of the oscillation function and detects position information of the magnetic head from the detected read signal. The magnetic head position control can be performed in the data area. The magnetic head position signal not dependent on the frequency of a sampling signal generated from the servo information area can be generated. This in turn improves the data recording density and allows a highly precise position control of the magnetic head, thus improving the reliability of the magnetic disk drive.

Abstract: In order to provide a high sensitivity variable gain amplifier, there is provided a structure in which at least one path comprising at least a stage of the voltage-input/voltage-output amplifier+ a stage of voltage-input/current-output amplifier and a path comprising a stage of the voltage-input/current-output amplifier are connected in parallel between the input terminal and output terminal or, a structure in which a plurality of paths each comprising at least a stage of voltage-input/voltage-output amplifier+a stage of voltage-input/current-output amplifier are connected in parallel between the input terminal and output terminal. A gain is switched by selecting and operating any one of paths. When any one path is selected, an input impedance viewed from the input terminal is suppressed almost not to change or an output impedance viewed from the output terminal is suppressed almost not to change. Thereby, a high sensitivity wireless receiver can be realized.

Abstract: An automatic gain adjustment circuit for automatically adjusting the gain and DC output voltage of an amplifier against power supply fluctuations, temperature fluctuations and process variations and the amplifier using the circuit are provided. The gain and the DC output voltage are adjusted by providing a bias circuit for adjusting the operating current or gain of an amplifying element, connecting a load to the output electrode of the amplifying element to form an output terminal, connecting a variable current source for adjusting the operating voltage or DC output voltage of the amplifying element to the output electrode, connecting a gain detection circuit and a DC output voltage detection circuit to the output terminal, and feed backing the respective outputs of the detection circuits to the variable current source. A reference AC signal is inputted for gain adjustment.

Abstract: A cyclic diamine compound of formula (1): 1

Abstract: A method for treating a pathological condition caused by reduced production of erythropoietin. The method includes administering to a subject an effective amount of N,N′-bis(5(3,4,5-trimethoxyphenyl)-4-pentenyl)homopiperazine, an acid-addition salt thereof, a hydrate of N,N′-bis(5-(3,4,5-trimethoxyphenyl)-4-pentenyl)homopiperazine, or a hydrate of the salt.

Abstract: A cyclic amine compound represented by the following general formula (1): 1

Abstract: A cyclic diamine compound of formula (1): wherein R1 and R2 are individually a hydrogen atom or a methoxy group, provided R1 is a methoxy group when R2 is a hydrogen atom, or a hydrogen atom when R2 is a methoxy group; A is an oxygen atom, a sulfur atom, CH═CH, CH═N or NR3, in which R3 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group; B is a nitrogen atom, CH or CR4, in which R4 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group; m is 1 or 2; and n is a number of 1 to 5, an acid-addition salt thereof, or a hydrate thereof. The compound has inhibitory effects on cell adhesion and is useful for treatment of allergy, asthma, rheumatism, arteriosclerosis, and inflammation.

Abstract: A thin-thickness variable resistor is provided, which is capable of stabilizing electrical connection between metallic terminals and a resistor by increasing the holding strength for a second terminal by a substrate while preventing the bending strain during the bending work from spreading to a conductive portion conductive to the resistor. A variable resistor comprises a substrate, metallic terminals formed in the substrate by insert-molding, and a slider sliding on a resistor formed on the substrate, wherein the slider is rotatably attached by crimping an eyelet formed in a first metallic terminal. External-connecting portions of the metallic terminals are extended from the bottom portion of the substrate to be bent upwardly along sides of the substrate.