Patents by Inventor Takeshi Isoda

Takeshi Isoda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11162940
    Abstract: Provided is at least one method of suppressing, in an immunoassay using surface plasmon-field enhanced fluorescence spectroscopy (SPFS), nonspecific signals generated by nonspecific adsorption of contaminants contained in a sample to an SPFS sensor section (e.g., a primary antibody, a solid-phase layer and a metal thin film). At least one method relates to a method of suppressing nonspecific signals originating from contaminants in an immunoassay using surface plasmon-field enhanced fluorescence spectroscopy (SPFS) (including cases where a receptor for a compound to be measured is used in place of a primary antibody), the method comprising performing at least one pretreatment.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: November 2, 2021
    Assignee: KONICA MINOLTA, INC.
    Inventors: Tomonori Kaneko, Takeshi Isoda
  • Publication number: 20210333133
    Abstract: A sensor unit attachable to a hole of a housing, closed by an overlay on one side in the first direction, from the other side in the first direction. The sensor unit includes a body, a sensor, a vibration generator, a vibration damper, and a fixable part. The body includes a first portion and a second portion on the other side in the first direction relative to the first portion. The sensor provided at the body detects a contact of a detection target with the overlay. The vibration generator can vibrate the body and sensor. The fixable part is provided at the second portion of the body. With the first portion accommodated in the hole, the fixable part is fixed to the housing from the other side in the first direction via the vibration damper, and the vibration damper is at least partly interposed between the fixable part and housing.
    Type: Application
    Filed: April 20, 2021
    Publication date: October 28, 2021
    Applicant: HOSIDEN CORPORATION
    Inventors: Masato Shimizu, Takeshi Isoda
  • Publication number: 20210311024
    Abstract: An object of the present invention is to provide a non-clinical test method which allows for the quality control of experimental animals having a transplanted tumor site, such as tumor-bearing mice, or experimental animals having a lesion site other than a transplanted a tumor site, and which is characterized by including the step of identifying, using a specimen collected from such an experimental animal, the profile of a lesion site, for example, a transplanted tumor site, of the experimental animal, by a quantitative technique.
    Type: Application
    Filed: February 15, 2017
    Publication date: October 7, 2021
    Applicant: Konica Minolta, Inc.
    Inventors: Hideki GOUDA, Takeshi SHIRAISHI, Takeshi ISODA, Noboru KOYAMA, Hisatake OKADA
  • Publication number: 20210292779
    Abstract: Plants are created with desired traits by conveniently and rapidly inhibiting methylation of target DNA in plants, without using recombination technology. Scaffold RNA produced by transcription of target DNA is cleaved in an RNA-directed DNA methylation mechanism.
    Type: Application
    Filed: July 25, 2019
    Publication date: September 23, 2021
    Inventors: Chikara MASUTA, Tsuyoshi INUKAI, Wataru MATSUNAGA, Reika ISODA, Takeshi MATSUMURA, Go ATSUMI
  • Publication number: 20210293786
    Abstract: The present invention relates to a method relating the evaluation of tumor tissue from an experimental animal, the method including the step of measuring an amount of a substance, except for human-derived tumor cells, contained in a sample collected from a region in an experimental animal into which a human-derived tumor tissue or tumor cells have been transplanted, wherein the region contains the tumor tissue or the tumor cells.
    Type: Application
    Filed: July 31, 2017
    Publication date: September 23, 2021
    Applicant: Konica Minolta, Inc.
    Inventors: Yoshikazu KURIHARA, Hideki GOUDA, Takeshi ISODA, Takeshi SHIRAISHI
  • Publication number: 20210277250
    Abstract: The present invention provides: an aminocoumarin compound having a structure represented by the following formula (1); and an aminocoumarin compound-containing resin particle containing the aminocoumarin compound and a resin particle containing the aminocoumarin compound. In formula (1), Rs each independently represent a hydrogen atom or a methyl group, Q represents a sulfur atom, an oxygen atom, or N—R1, and R1 represents a hydrogen atom or a methyl group. The aminocoumarin compound of the present invention is a fluorescent dye that has a longer excitation wavelength than a conventionally known sulfonated coumarin-based compound and is effectively excited at a wavelength of 475 nm or more, particularly at a wavelength around 500 nm.
    Type: Application
    Filed: February 13, 2018
    Publication date: September 9, 2021
    Inventors: Kensaku TAKANASHI, Shin NAKAYAMA, Kenji NISHIKAWA, Takeshi ISODA
  • Patent number: 10953638
    Abstract: A plastic laminate structure including layers laminated together, a functional element being an electrode, a display element, an antenna, or a sensor on a second layer of the layers, conductive lines on the second layer, and a dummy conductor on one of the layers. The layers include a first layer of a plastic material and the second layer fixed to the first layer. The first conductive lines are connected to the functional element. The dummy conductor surrounds the functional element and the conductive lines. Each conductive line includes a parallel portion forming at least part of each conductive line. First and second distances are each 500 ?m or less. The first distance is a distance in the array direction between the parallel portions. The second distance is a distance between the endmost conductive line and the dummy conductor in a plane direction extending along a face of the second layer.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: March 23, 2021
    Assignee: HOSIDEN CORPORATION
    Inventors: Takeshi Isoda, Naoki Shiga
  • Publication number: 20210011007
    Abstract: The present invention relates to fluorescent premix particles, a fluorescent stain containing the same, and a fluorescent staining method in which these are used, and the fluorescent premix particles are particles including: phosphor integrated particles that are modified with a first reactive substance; and at least one target protein-binding substance that is modified with a second reactive substance and is selected from the group consisting of an antibody and an aptamer, wherein the phosphor integrated particles and the at least one target protein-binding substance are linked by interaction between the first reactive substance and the second reactive substance.
    Type: Application
    Filed: April 7, 2017
    Publication date: January 14, 2021
    Inventors: Takeshi ISODA, Daisuke TOMIOKA
  • Patent number: 10746740
    Abstract: There is provided a biological substance quantitation method of quantitating a biological substance in a sample stained with a staining reagent including a fluorescent particle encapsulating a fluorescent substance, based on a fluorescence of the fluorescent substance. The method includes inputting a fluorescent image representing expression of the biological substance in the sample by a fluorescent bright spot; and quantitating an expression amount of the biological substance based on a fluorescence of the fluorescent bright spot. The biological substance is a nucleoprotein expressed at a cell nucleus. The fluorescent particle binds to the biological substance through a primary antibody which is directed against the biological substance as an antigen.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: August 18, 2020
    Assignee: Konica Minolta, Inc.
    Inventors: Takeshi Isoda, Naoko Furusawa, Yasuyuki Motokui, Kohsuke Gonda, Noriaki Ohuchi, Mika Watanabe
  • Patent number: 10556399
    Abstract: A plastic laminate structure including a plurality of, or a plurality of kinds of, plastic layers and an adhesive layer. The plastic layers are laminated together in a first direction. All the plastic layers are comprised exclusively of extruded plastic layers. The adhesive layer affixes together two of the plastic layers that are adjacent to each other in the first direction.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: February 11, 2020
    Assignee: HOSIDEN CORPORATION
    Inventors: Takeshi Isoda, Naoki Shiga
  • Publication number: 20200003764
    Abstract: The present invention relates to a method for manufacturing a purified product of a protein-modified phosphor-integrated particle, a method for manufacturing a fluorescent staining liquid, a purified product of a protein-modified phosphor-integrated particle, and a filter for purifying a fluorescent staining liquid and a protein-modified phosphor-integrated particle, in which the method for manufacturing a purified product of a protein-modified phosphor-integrated particle includes a purification step for separating protein-modified phosphor-integrated particles from an impurity by bringing a solution containing the phosphor-integrated particles (protein-modified phosphor-integrated particles), of which surfaces are modified with a biological substance-binding protein, and the impurity originating from the manufacturing process thereof into contact with a filter having a substance (protein-binding substance) capable of reversibly binding to the biological substance-binding protein supported thereon.
    Type: Application
    Filed: April 7, 2017
    Publication date: January 2, 2020
    Inventor: Takeshi ISODA
  • Patent number: 10502743
    Abstract: The present invention provides a method by which lung squamous cell carcinoma can be detected in a simple and prompt manner with high detection performance; and the like. The method according to the present invention detects lung squamous cell carcinoma by an assessment including the steps of: (1) performing measurement of the desmoglein 3 content in a blood sample collected from a subject; and (2) comparing the desmoglein 3 content determined by the measurement with the desmoglein 3 content in a blood sample collected from a healthy individual so as to estimate the presence of lung squamous cell carcinoma in the subject when the desmoglein 3 content is higher in the blood sample collected from the subject.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: December 10, 2019
    Assignees: KONICA MINOLTA, INC., CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: Takeshi Isoda, Nao Noro, Tomonori Kaneko
  • Publication number: 20190275769
    Abstract: A plastic laminate structure including layers laminated together, a functional element being an electrode, a display element, an antenna, or a sensor on a second layer of the layers, conductive lines on the second layer, and a dummy conductor on one of the layers. The layers include a first layer of a plastic material and the second layer fixed to the first layer. The first conductive lines are connected to the functional element. The dummy conductor surrounds the functional element and the conductive lines. Each conductive line includes a parallel portion forming at least part of each conductive line. First and second distances are each 500 ?m or less. The first distance is a distance in the array direction between the parallel portions. The second distance is a distance between the endmost conductive line and the dummy conductor in a plane direction extending along a face of the second layer.
    Type: Application
    Filed: March 7, 2019
    Publication date: September 12, 2019
    Applicant: HOSIDEN CORPORATION
    Inventors: Takeshi ISODA, Naoki SHIGA
  • Patent number: 10323271
    Abstract: Provided are: a probe reagent which is capable of stably yielding a fluorescence signal in FISH while inhibiting non-specific adsorption by the use of a nucleic acid molecule having a smaller number of bases than a BAC probe; and FISH using the probe reagent. The probe reagent is for in situ hybridization and comprises: phosphor-integrated nanoparticles containing phosphors integrated therein; and a nucleic acid molecule having a prescribed nucleic acid sequence, which phosphor-integrated nanoparticles and nucleic acid molecule are bound with each other.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: June 18, 2019
    Assignee: KONICA MINOLTA, INC.
    Inventors: Takeshi Isoda, Mitsuru Sekiguchi, Yutaka Hatanaka, Yoshikazu Kurihara
  • Publication number: 20190064961
    Abstract: A plastic laminate structure accommodatable in a casing with an opening. The plastic laminate structure includes a base film made of a plastic material, at least one intermediate layer and a plastic layer. The base film includes outer and inner faces. The outer face has an exposed region externally visible through the opening of the casing. The inner face includes a first region corresponding to the exposed region. The at least one intermediate layer has an external size equal to or larger than that of the first region, and is laminated on the inner face of the base film so as to cover the entire first region of the inner face of the base film. The plastic layer is fixed to both the inner face of the base film and the intermediate layer, or alternatively to the intermediate layer, so as to cover the at least one intermediate layer.
    Type: Application
    Filed: August 2, 2018
    Publication date: February 28, 2019
    Inventors: Takeshi Isoda, Naoki Shiga
  • Publication number: 20190033181
    Abstract: An object of the present invention is to provide: a staining agent for tissue staining which has an improved fluorescence signal evaluation accuracy; and a tissue staining kit comprising the staining agent. The staining agent for tissue staining contains, as a staining component, dye-resin particles comprising thermosetting resin particles and a fluorescent dye immobilized on the resin particles, wherein the resin particles contains a substituent having an electric charge opposite to that of the fluorescent dye and forms an ionic bond or a covalent bond with the fluorescent dye, and the dye-resin particles have a particle size variation coefficient of 15% or less.
    Type: Application
    Filed: October 3, 2018
    Publication date: January 31, 2019
    Inventors: Kensaku TAKANASHI, Yasushi Nakano, Takeshi Isoda, Hideki Gouda
  • Patent number: 10154602
    Abstract: The invention provides a device module that can be manufactured with a die. The device module includes a plastic part, a device, a holder, and an external connection. The device is embedded in the plastic part. The holder is embedded in the plastic part and includes an exposed portion exposed from the plastic part in a thickness direction of the plastic part in such a manner as to close a housing recess of the die. The external connection is connected to the device and partially fixed to the holder. The external connection includes a lead-out portion insertable in the housing recess of the die. The lead-out portion is embedded in the plastic part and being led out of the plastic part in the thickness direction. Alternatively, the lead-out portion is led through and out of the holder in the thickness direction.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: December 11, 2018
    Assignee: HOSIDEN CORPORATION
    Inventors: Takeshi Isoda, Koji Shinoda
  • Patent number: 10101249
    Abstract: An object of the present invention is to provide: a staining agent for tissue staining which has an improved fluorescence signal evaluation accuracy; and a tissue staining kit comprising the staining agent. The staining agent for tissue staining contains, as a staining component, dye-resin particles comprising thermosetting resin particles and a fluorescent dye immobilized on the resin particles, wherein the resin particles contains a substituent having an electric charge opposite to that of the fluorescent dye and forms an ionic bond or a covalent bond with the fluorescent dye, and the dye-resin particles have a particle size variation coefficient of 15% or less.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: October 16, 2018
    Assignee: Konica Minolta, Inc.
    Inventors: Kensaku Takanashi, Yasushi Nakano, Takeshi Isoda, Hideki Gouda
  • Publication number: 20180275134
    Abstract: There is provided a biological substance quantitation method of quantitating a biological substance in a sample stained with a staining reagent including a fluorescent particle encapsulating a fluorescent substance, based on a fluorescence of the fluorescent substance. The method includes inputting a fluorescent image representing expression of the biological substance in the sample by a fluorescent bright spot; and quantitating an expression amount of the biological substance based on a fluorescence of the fluorescent bright spot. The biological substance is a nucleoprotein expressed at a cell nucleus. The fluorescent particle binds to the biological substance through a primary antibody which is directed against the biological substance as an antigen.
    Type: Application
    Filed: January 15, 2016
    Publication date: September 27, 2018
    Inventors: Takeshi ISODA, Naoko FURUSAWA, Yasuyuki MOTOKUI, Kohsuke GONDA, Noriaki OHUCHI, Mika WATANABE
  • Publication number: 20180162029
    Abstract: A film insert molded article including a film insert and a molded plastic body. The film insert includes a first and a second main face on one and the other sides, respectively, in the thickness direction and a side face extending from the first to the second face. The molded plastic body includes a main body, which is fixed directly to the first main face, and a fixing portion with a cross section in the thickness direction of generally inverted L-shape. The fixing portion includes a first and a second fixing portion. The first fixing portion extends from the main body along the side face of the film insert and is fixed directly to a part or whole of the side face. The second fixing portion extends from the first fixing portion along the second main face and is fixed directly to the end portion of the second main face.
    Type: Application
    Filed: December 7, 2017
    Publication date: June 14, 2018
    Inventors: Naoki Shiga, Takeshi Isoda