Abstract: A therapeutic and/or prophylactic agent for a solid tumor, which comprises a thiadiazoline derivative represented by the general formula (I), or a pharmaceutically acceptable salt thereof: [wherein, n represents an integer of 1 to 3, R1 represents a hydrogen atom, R2 represents lower alkyl, or R1 and R2 are combined together to represent alkylene, R3 represents lower alkyl, R4 represents NHSO2R6 (wherein R6 represents hydroxy or the like) or the like, and R5 represents aryl or the like] and the like are provided.

Abstract: (wherein R represents lower alkyl; R1 represents a hydrogen atom, —CH2X or —OC(?O)R3; and R2 represents a hydrogen atom, nitro, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy, substituted or unsubstituted lower alkylthio or substituted or unsubstituted aryl) The present invention provides a simple industrial process for producing pyrazoloacridone derivatives having an antitumor activity, 1-(2-carboxyphenyl)indazole derivatives, which are useful as synthetic intermediates thereof, or the like; and the like.

Abstract: The present invention provides a process for producing 2-halobenzoic acids of the general formula (I), characterized by reacting a benzoic acid of formula (II) with a halogenating agent in the presence of Pd catalyst: (wherein A is —OH, —OM (M is alkali metal), —N(R6)R7 (R6 and R7 are each H, C1–C6 alkyl, optionally substituted phenyl, or the like); R is H, C1–C6 alkyl, C1–C6 alkylcarbonyl, carboxyl, C1–C12 alkoxycarbonyl, optionally substituted phenylcarbonyl, or the like; n is 0 to 4; X is Cl, Br or I, or alternatively (R)n may be present on benzene-constituting carbon atoms adjacent to each other and form a C3–C4 alkylene- or C3–C4 alkenylene-fused ring).

Abstract: Heterocyclic dicarboxylic acid diamide derivative represented by the general formula (I): wherein R1, R2 and R3 represent each H, optionally halogenated C3-6 cycloalkyl, etc.; Het represents a 5- or 6-membered heterocycle; X and Y represent each halocyano, nitro, optionally halogenated C3-6, cycloalkyl, optionally substituted phenyl, an optionally substituted heterocycle, etc; n is from 0 to 3; m is from 1 to 5; Z1 and Z2 represent each O or S; and B1 to B4 represent each C or N. Agricultural/horticultural insecticides having an excellent controlling effect on pest insects such as diamond-back moth (Pluntella xylostella) and tobacco cutworm (Spodoptera litura).

Abstract: The present invention provides a process for producing 2-halobenzoic acids of the general formula (I), characterized by reacting a benzoic acid of formula (II) with a halogenating agent in the presence of Pd catalyst: 1

Abstract: A fused heterocyclic dicarboxylic acid diamide derivative represented by general formula (I): 1

Abstract: A fused heterocyclic dicarboxylic acid diamide derivative represented by formula (I): wherein R1 is H, (C1-C6) alkyl; R2 and R3 are H, (halo) (C1-C6) alkyl, (C3-C8) cycloalkyl, substituted amino (C1-C6) alkyl, (substituted) phenyl (C1-C6) alkyl, (substituted) phenyl (C1-C6) alkoxy or the like or R2 and R3, taken conjointly, represent a (substituted) 5- or 6-membered heterocycle having at least one of O, S and N; X is H, halogen, NO2, CN, (C1-C6) alkyl, (substituted) phenyl, (substituted) phenoxy or the like; is or the like wherein Y, R4 and R9 are H, halogen, NO2, CN, (C1-C6) alkyl or the like, and A, B, D, E, F, G, J and K are O, S, N, sulfinyl or the like; and a herbicide containing said derivative as active ingredient.

Abstract: The present invention provides a pyridine-2,3-dicarboxylic acid diamide derivatives represented by the following formula (I) and herbicides containing them as an active ingredient. ##STR1## ?wherein R.sub.1 represents one to three substituents such as H, halogen, cyano, nitro, (halo)alkyl, (halo)alkoxy, (halo)alkylthio, (C.sub.3-6)cycloalkyl, alkenyl, alkynyl, substituted phenyl, substituted phenoxy, etc. and R.sub.1 may represent alkylene or alkenylene together with an adjacent carbon atom; R.sub.2 represents H, halogen, cyano, nitro, (halo)alkyl or (halo)alkoxy; R.sub.3 represents H or alkyl; R.sub.4 and R.sub.5 each represent H, (halo)alkyl, cycloalkyl, substituted cycloalkylalkyl, etc.; and n represents an integer of 0 or 1!.The present compounds exhibit excellent effect for controlling paddy field weeds and the like.