Abstract: Provided are novel antibody-pyrrolodiazepine derivatives and novel antibody-pyrrolodiazepine derivative conjugates, as well as methods of using the same, and a novel CLDN6 and/or CLDN9 antibody. The disclosed compounds are of the class of alkyl benzene sulfonyl ureas, useful as oral anti-diabetics, and include substituted benzo[e]pyrrolo[1,2-?][1,4]diazepine.

Abstract: An electrode production method that can suppress the thickness nonuniformity in an electrode is provided. The electrode production method includes: forming a first active material layer on a first face of a current collector; pressing the first active material layer for the first time; and pressing the first active material layer for the second time after said first pressing, wherein the proportion of a pressing linear pressure P2 in said second pressing to a pressing linear pressure P1 in said first pressing is 100% to 200%.

Abstract: Provided is a chemical-mechanical polishing composition comprising an abrasive, a basic component, at least one compound selected from the group consisting of a quaternary polyammonium salt, a quaternary ammonium salt having 6 or more carbon atoms, and an alkylated polymer having an amide structure, and an aqueous carrier; a rinse composition comprising the at least one compound and an aqueous carrier, as well as a method of chemically-mechanically polishing a substrate, and a method of rinsing a substrate, in which the respective compositions are used.

Abstract: The bonded substrate includes the silicon nitride ceramic substrate, a copper plate, the bonding layer, and penetrating regions. The copper plate and the bonding layer are patterned into a predetermined shape, and are disposed over a main surface of the silicon nitride ceramic substrate. The bonding layer bonds the copper plate to the main surface of the silicon nitride ceramic substrate. The penetrating regions each include one or more penetrating portions penetrating continuously from the main surface of the substrate into the silicon nitride ceramic substrate to a depth of 3 ?m or more and 20 ?m or less, and contain silver, and the number of penetrating regions present per square millimeter of the main surface of the substrate is one or more and 30 or less.

Abstract: Provided are novel antibody-pyrrolodiazepine derivative and novel antibody-pyrrolodiazepine derivative conjugates, as well as methods of using the same, and a novel CLDN6 and/or CLDN9 antibody. The disclosed compounds are of the class of alkyl benzene sulfonyl ureas, useful as oral anti-diabetics, and include substituted benzo[e]pyrrolo[1,2-?][1,4]diazepine.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibodydrug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-Lb-Lc- wherein the antibody is connected to the terminal of L1, and the antitumor compound is connected to the terminal of Lc with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: A light source apparatus is provided with the emission section in which a plurality of vertical-cavity surface-emitting laser light-emitting elements is arrayed, the driving circuit section that causes the plurality of light-emitting elements of the emission section to emit light, the temperature detection section that includes a plurality of temperature sensors arranged to detect the temperature of the emission section, and a control section. The control section is configured to, during an emission target period when the light-emitting elements of the emission section are driven by the driving circuit section, correct a detection value from each of the plurality of temperature sensors by using a correction value set for each of the temperature sensors.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-Lb-Lc- wherein the antibody is connected to the terminal of L1, and the antitumor compound is connected to the terminal of Lc with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: Provided is a method of manufacturing a crystallized stacked structural body excellent in manufacturing efficiency. The present invention is characterized by including: a stacked structural body forming step of forming a stacked structural body (7) in which an Sb2Te3 layer (5) having a thickness of from 2 nm to 10 nm and a GeTe layer (6) having a thickness of more than 0 nm and 4 nm or less are stacked, and a trace addition element (S or Se) is incorporated at a content of from 0.05 at % to 10.0 at % into the GeTe layer (6) on an orientation control layer (4) configured to give, to the Sb2Te3 layer (5) and the GeTe layer (6) at the time of their crystallization, a common crystal axis, the step being performed under a temperature of less than 100° C. including room temperature; an Sb2Te3 layer-crystallizing step of crystallizing the Sb2Te3 layer (5) by heating and holding the stacked structural body (7) at a first crystallization temperature of 100° C. or more and less than 170° C.

Abstract: An operation log acquisition device includes processing circuitry configured to store a determination image that is an image of a characteristic area of an operation screen that is used to perform a predetermined operation, an event occurrence area in which an event may occur when the predetermined operation is performed, operation type specifying information that specifies an operation type, and an acquisition image area that is to be acquired when the predetermined operation is performed, in association with each other, upon detecting an occurrence of the event, acquire an occurrence time of the event, an occurrence position of the event, and a captured image of the operation screen, and determine whether or not the captured image acquired includes a matching area that the determination image matches, and acquire an event occurrence area of the determination image if the captured image includes the matching area.

Abstract: A lighting device includes a substrate, a first conductive portion, a second conductive portion disposed with a spacing as to the first conductive portion, a first reflective layer having a first opening coinciding with the first conductive portion and a second opening coinciding with the second conductive portion, a light-emitting part connected to the first conductive portion through the first opening, a non-light-emitting part connected to the second conductive portion through the second opening, and a second reflective layer. The second reflective layer includes a first reflective portion disposed around the light-emitting part, and a second reflective portion disposed around the non-light-emitting part.

Abstract: The present invention provides a novel antibody-pyrrolodiazepine derivative and a novel antibody-pyrrolodiazepine derivative conjugate using the same, and a novel CLDN6 and/or CLDN9 antibody.

Abstract: A management device obtains a first operational process, which is an operational process described in an operational procedure manual for an application, and a second operational process, which is an operational process performed by a user on the application. The management device further determines whether the first operational process is consistent with the second operational process or not. If the management device determines that the first operational process is not consistent with the second operational process, the management device displays a review screen to check inconsistency between the operational processes.

Abstract: A lighting device includes a substrate, a first conductive portion, a second conductive portion disposed with a spacing as to the first conductive portion, a first reflective layer having a first opening coinciding with the first conductive portion and a second opening coinciding with the second conductive portion, a light-emitting part connected to the first conductive portion through the first opening, a non-light-emitting part connected to the second conductive portion through the second opening, and a second reflective layer. The second reflective layer includes a first reflective portion disposed around the light-emitting part, and a second reflective portion disposed around the non-light-emitting part.

Abstract: A debug information abstraction unit (32) of a proxy server (30) adds, when a predetermined rule of an extension program is embodied into a program, a program for outputting debug information regarding the predetermined rule to the embodied program. Then, a debug information transmission unit (41b) of a terminal device (40) transmits, to a debug support device (10), the debug information regarding the predetermined rule for which the program has been added.

Abstract: An illumination device includes a plurality of light sources, each having a light-emission surface that faces a side opposite to a display panel; a light-source substrate that has a mount surface on a side opposite to the display panel, and that has light transmissivity, the mount surface being provided for mounting the plurality of light sources thereon; and a reflecting layer that is provided on a side of the light-source substrate opposite to the display panel so as to be spaced from the light-emission surfaces by a predetermined interval, and that reflects toward the light-source substrate light coming from the light sources, wherein the illumination device illuminates the display panel with light.

Abstract: A lighting device includes a plurality of light sources arranged side by side in a plane and a wavelength conversion sheet arranged to face a light emitting surface of each of the light sources and converting a wavelength of light from the light sources, in which the wavelength conversion sheet includes a base material having transparency, and a wavelength conversion layer in which a plurality of protrusions containing a wavelength conversion material and having a spherical surface are arranged side by side without gaps on a principal surface of the base material opposite to the light sources.

Abstract: An illumination device includes a light source, a first optical member, and a fixing portion. The first optical member includes a light reflection portion configured to reflect light, at least a part of the light reflection portion overlapping with the light source, and a light transmitting portion configured to transmit light, the light transmitting portion not overlapping the light reflection portion. A center of the light source in a plan view is defined as a first center, and a center of the light reflection portion in a plan view is defined as a second center. In the light reflection portion, the second center is located between the fixing portion and the first center at a first temperature, and at a second temperature higher than the first temperature, a position of the second center is closer to the first center than a position of the second center at the first temperature.

Abstract: An illumination device includes a light source, a first optical member, and a fixing portion. The first optical member includes a light reflection portion configured to reflect light, at least a part of the light reflection portion overlapping with the light source, and a light transmitting portion configured to transmit light, the light transmitting portion not overlapping the light reflection portion. A center of the light source in a plan view is defined as a first center, and a center of the light reflection portion in a plan view is defined as a second center. In the light reflection portion, the second center is located between the fixing portion and the first center at a first temperature, and at a second temperature higher than the first temperature, a position of the second center is closer to the first center than a position of the second center at the first temperature.

Abstract: A display control device has display setting information including setting information of a layer structure of display objects on a terminal screen and setting information of a group to which the display objects belong, display state information indicating a display state of the display object, and operation setting information defining which setting content a combination of an operation target and operation content on a screen indicate for a layer structure and a group of display objects for each combination of the operation target and the operation content. The display control device specifies the setting content to the display object based on the combination of the operation target and the operation content, the display state information, and the operation setting information when an operation on the display object occurs.