Abstract: The present invention provides positively or negatively charged nanobubbles, with the goal to clarify the effects of positively or negatively charged nanobubbles on microorganism and plant growth. The present invention also provides charged nanobubble dispersion liquid that contains 105 to 1010 fine bubbles. The fine bubbles are dispersed in the liquid, are positively or negatively charged, have an average particle size of 10 nm to 500 nm, and have a zeta potential of 10 mV to 200 mV.

Abstract: The present invention provides a method for effectively utilizing a nanobubble dispersion liquid and/or a microbubble dispersion liquid in medical treatment. In the present invention, the nanobubble dispersion liquid containing nanobubbles that are positively or negatively charged, and that have an average particle size of 10 nm to 500 nm is brought into contact with pathogenic microorganisms, which improves an antibacterial effect against pathogenic microorganisms, and/or the microbubble dispersion liquid containing microbubbles that are positively or negatively charged, having an average particle size of 1 ?m to 900 ?m is brought into contact with the affected area to crush and wash bloody or non-bloody infectious viscous excrement or exudate, or crush and remove a blood clot.

Abstract: A method includes providing an indwelling tool having a magnetic body at the inside of a luminal organ by inserting the tool into a working channel inserted from a natural opening of a living body to the luminal organ, in a manner such that an axis along a length of the magnetic body is arranged substantially parallel to a length direction of the working channel; disposing the tool in a vicinity of a diseased part of the luminal organ; applying a magnetic field to the magnetic body by using a magnetic field generating device provided at the outside of the luminal organ, so as to attract the magnetic body and make a side face of the magnetic body along the axis thereof push against a tissue in the vicinity of the diseased part; and lifting a tissue around a position of the tool, which includes the diseased part, by applying a magnetic force to the magnetic body by using the magnetic field generating device.

Abstract: A method includes providing an indwelling tool having a magnetic body at the inside of a luminal organ by inserting the tool into a working channel inserted from a natural opening of a living body to the luminal organ, in a manner such that an axis along a length of the magnetic body is arranged substantially parallel to a length direction of the working channel; disposing the tool in a vicinity of a diseased part of the luminal organ; applying a magnetic field to the magnetic body by using a magnetic field generating device provided at the outside of the luminal organ, so as to attract the magnetic body and make a side face of the magnetic body along the axis thereof push against a tissue in the vicinity of the diseased part; and lifting a tissue around a position of the tool, which includes the diseased part, by applying a magnetic force to the magnetic body by using the magnetic field generating device.

Abstract: The purpose of the present invention is to provide a liquid supply device and biological cleaning device that, by supplying a sterile liquid including low-flow, low-pressure microbubbles, can dramatically increase cleaning effects and clean quickly and neatly without damaging a biological tissue. A liquid supply device 3, having a supply flow path 2 for supplying a liquid containing microbubbles to a cleaning instrument 1 for cleaning an organism and to a cleaning target such as a medical instrument, is characterized by being provided with a tube pump 5 for delivering the liquid to the supply flow path 2 and a microbubble generator B that is provided midway on the supply flow path 2 and is for causing microbubbles to be generated in the liquid.

Abstract: Provided is a technique for washing a body fluid, a foreign body or excrement in a living body rapidly and cleanly without damaging biological tissues. A body fluid, a foreign body or excrement in a living body can be washed by bringing the body fluid, the foreign body or the excrement into contact with a washing solution containing micro-bubble water.

Abstract: A surgical system for small-pit closure in hollow organs is provided. The surgical system is provided with a surgical device for small-pit closure in hollow organs, with the surgical device including the following components: a suture-member cartridge in which a pair of parallel tubular members that accommodate respective suture members are feedably connected to the rear ends of a pair of arrow-shaped members that latch into tissue in a hollow organ; an auxiliary shooting unit having plungers respectively provided in a pair of cylinders open at both ends; a hollow-organ-insertable unit configured of a pair of flexible air tubes; and a gas shooter that sequentially discharges compressed air or high-pressure gas into the open-ended cylinders in response to operations of a trigger, for sequentially ejecting the arrow-shaped members and driving the same into tissue in the hollow organ on both sides of a small pit site.

Abstract: A system and method for use in NOTES is provided for reducing surgical invasiveness. An insertion body that is connected by an anvil assembly and joined to a thin wire guide or electric guide wire, is inserted via a natural orifice into a hollow organ so as to incise and remove a diseased or defective site from the hollow organ by using a pair of or front-end/rear-end linear cutters of a linear cutting/stapling device or linear stapler, after which the two cut ends of the tract are anastomosed and recovered by a circular anastomosis surgical stapler that is provided with the system.

Abstract: A surgical system for small-pit closure in hollow organs is provided. The surgical system is provided with a surgical device for small-pit closure in hollow organs, with the surgical device including the following components: a suture-member cartridge in which a pair of parallel tubular members that accommodate respective suture members are feedably connected to the rear ends of a pair of arrow-shaped members that latch into tissue in a hollow organ; an auxiliary shooting unit having plungers respectively provided in a pair of cylinders open at both ends; a hollow-organ-insertable unit configured of a pair of flexible air tubes; and a gas shooter that sequentially discharges compressed air or high-pressure gas into the open-ended cylinders in response to operations of a trigger, for sequentially ejecting the arrow-shaped members and driving the same into tissue in the hollow organ on both sides of a small pit site.

Abstract: A medical holding apparatus provided with an anchor member composed of a tying-up portion to be tied up to an intracorporeal tissue and a first connection portion; and a locking member composed of a holding portion for holding another intracorporeal tissue, a medical instrument or a drug and a second connection portion, in which the first connection portion and the second connection portion can be detachably connected to each other.

Abstract: A lifting method for a lesion area of the present invention includes: a step of introducing an anchoring tool having a magnetic body and an anchor into a hollow organ having a lesion area, by using a working channel inserted from a natural opening into the hollow organ; a step of anchoring the anchoring tool, by sequentially placing the anchor in a predetermined position around the lesion area, so as to arrange a plurality of the magnetic bodies around the lesion area; and a step of lifting a tissue including the lesion area, by attracting the magnetic bodies using the magnetic field generation tool arranged on the outside of the hollow organ.

Abstract: A system and method for use in NOTES is provided for reducing surgical invasiveness. An insertion body that is connected by an anvil assembly and joined to a thin wire guide or electric guide wire, is inserted via a natural orifice into a hollow organ so as to incise and remove a diseased or defective site from the hollow organ by using a pair of or front-end/rear-end linear cutters of a linear cutting/stapling device or linear stapler, after which the two cut ends of the tract are anastomosed and recovered by a circular anastomosis surgical stapler that is provided with the system.

Abstract: The present invention enables the desired area on a luminal organ to be held correctly during laparotomy or laparoscopic surgery, even without carrying out dot inking which requires a high degree of skill. In the present invention, a magnetic body is pre-anchored at a specific position inside a luminal organ. During surgery, a magnet is brought close to the outside of the luminal organ, such that the magnetic body is adsorbed to the magnet, along with the body tissue of the luminal organ, enabling traction.

Abstract: A medical holding apparatus provided with an anchor member composed of a tying-up portion to be tied up to an intracorporeal tissue and a first connection portion; and a locking member composed of a holding portion for holding another intracorporeal tissue, a medical instrument or a drug and a second connection portion, in which the first connection portion and the second connection portion can be detachably connected to each other.

Abstract: The present invention enables the desired area on a luminal organ to be held correctly during laparotomy or laparoscopic surgery, even without carrying out dot inking which requires a high degree of skill. In the present invention, a magnetic body is pre-anchored at a specific position inside a luminal organ. During surgery, a magnet is brought close to the outside of the luminal organ, such that the magnetic body is adsorbed to the magnet, along with the body tissue of the luminal organ, enabling traction.