Patents by Inventor Takeshi Ohshima

Takeshi Ohshima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10273916
    Abstract: An internal combustion engine including an intake passage fuel injection valve for injecting fuel into an intake passage and a cylinder inside fuel injection valve for injecting fuel into a combustion chamber, includes: a fuel pump pressurizing and feeding fuel, which is fed from a fuel tank, to the cylinder inside fuel injection valve; a securing part provided on a cylinder head member of the internal combustion engine to secure the fuel pump; an introducing member having heat conductivity, the introducing member connected to the fuel pump and formed with: a first introducing path for introducing fuel from the fuel tank to the fuel pump; and a second introducing path for introducing fuel from the fuel tank to the intake passage fuel injection valve; and a heat transmitting member transmitting heat between the introducing member and the securing part.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: April 30, 2019
    Assignee: MITSUBISHI JIDOSHA KOGYO KABUSHIKI KAISHA
    Inventors: Kenichi Nozu, Tadanori Minoura, Takeshi Ohshima, Genki Kurimoto
  • Publication number: 20170284353
    Abstract: An internal combustion engine including an intake passage fuel injection valve for injecting fuel into an intake passage and a cylinder inside fuel injection valve for injecting fuel into a combustion chamber, includes: a fuel pump pressurizing and feeding fuel, which is fed from a fuel tank, to the cylinder inside fuel injection valve; a securing part provided on a cylinder head member of the internal combustion engine to secure the fuel pump; an introducing member having heat conductivity, the introducing member connected to the fuel pump and formed with: a first introducing path for introducing fuel from the fuel tank to the fuel pump; and a second introducing path for introducing fuel from the fuel tank to the intake passage fuel injection valve; and a heat transmitting member transmitting heat between the introducing member and the securing part.
    Type: Application
    Filed: March 29, 2017
    Publication date: October 5, 2017
    Applicant: MITSUBISHI JIDOSHA KOGYO KABUSHIKI KAISHA
    Inventors: Kenichi NOZU, Tadanori MINOURA, Takeshi OHSHIMA, Genki KURIMOTO
  • Patent number: 8440824
    Abstract: To provide a method for producing pyrimidine compound useful as an intermediate for agricultural chemicals or pharmaceuticals, which is simple in operation, presents high yield and produces only a small amount of by-products. The method comprises reacting a compound represented by the formula (I) with a compound represented by the formula (II) in the presence of a pyridine compound to produce a compound represented by the formula (III), a compound represented by the formula (IV) or their mixture.
    Type: Grant
    Filed: April 16, 2009
    Date of Patent: May 14, 2013
    Assignee: Ishihara Sangyo Kaisha, Ltd.
    Inventors: Shigeo Murai, Ryoji Koto, Hiroshi Yoshizawa, Takeshi Ohshima, Katsuyoshi Murakami, Takao Awazu, Hisayoshi Jonishi, Takayoshi Ando, Tadashi Nakamura, Norio Adachi, Akihiko Isogai
  • Patent number: 8338612
    Abstract: Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with simple operations by using industrially advantageous reaction systems by a process comprising (1) a step of reacting ACTF and DCDNBTF in the presence of an alkali component, a solvent selected from the group consisting of ketones, nitriles, ethers and esters and a sufficient amount of water to substantially dissolve the alkali component, (2) a step of neutralizing or acidifying the reaction mixture with an acid and (3) a step of removing the solvent by distillation from the mixture containing fluazinam as the reaction product and the reaction solvent to precipitate crystals the product.
    Type: Grant
    Filed: July 29, 2008
    Date of Patent: December 25, 2012
    Assignee: Ishihara Sangyo Kaisha, Ltd.
    Inventors: Shigeo Murai, Hiroshi Yoshizawa, Takeshi Ohshima, Katsuyoshi Murakami, Takayoshi Ando, Tadashi Nakamura, Norio Adachi, Akihiko Isogai
  • Publication number: 20110021774
    Abstract: To provide a method for producing pyrimidine compound useful as an intermediate for agricultural chemicals or pharmaceuticals, which is simple in operation, presents high yield and produces only a small amount of by-products. The method comprises reacting a compound represented by the formula (I) with a compound represented by the formula (II) in the presence of a pyridine compound to produce a compound represented by the formula (III), a compound represented by the formula (IV) or their mixture.
    Type: Application
    Filed: April 16, 2009
    Publication date: January 27, 2011
    Applicant: Ishihara Sangyo Kaisha, Ltd.
    Inventors: Shigeo Murai, Ryoji Koto, Hiroshi Yoshizawa, Takeshi Ohshima, Katsuyoshi Murakami, Takao Awazu, Hisayoshi Jonishi, Takayoshi Ando, Tadashi Nakamura, Norio Adachi, Akihiko Isogai
  • Patent number: 7858615
    Abstract: The present invention is directed to (S)-(?)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared with (S)-(?)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride anhydrous crystals and thus, exhibits excellent chemical stability.
    Type: Grant
    Filed: November 29, 2005
    Date of Patent: December 28, 2010
    Assignees: Kowa Co., Ltd., D. Western Therapeutics Institute, Inc.
    Inventors: Takeshi Ohshima, Hiroyoshi Hidaka, Masami Shiratsuchi, Kazuhiro Onogi, Toshiaki Oda
  • Publication number: 20100197930
    Abstract: Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with simple operations by using industrially advantageous reaction systems by a process comprising (1) a step of reacting ACTF and DCDNBTF in the presence of an alkali component, a solvent selected from the group consisting of ketones, nitriles, ethers and esters and a sufficient amount of water to substantially dissolve the alkali component, (2) a step of neutralizing or acidifying the reaction mixture with an acid and (3) a step of removing the solvent by distillation from the mixture containing fluazinam as the reaction product and the reaction solvent to precipitate crystals the product.
    Type: Application
    Filed: July 29, 2008
    Publication date: August 5, 2010
    Applicant: Ishihara Sangyo Kaisha Ltd
    Inventors: Shigeo Murai, Hiroshi Yoshizawa, Takeshi Ohshima, Katsuyoshi Murakami, Takayoshi Ando, Tadashi Nakamura, Norio Adachi, Akihiko Isogai
  • Publication number: 20080021018
    Abstract: The present invention is directed to (S)-(?)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared with (S)-(?)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride anhydrous crystals and thus, exhibits excellent chemical stability.
    Type: Application
    Filed: November 29, 2005
    Publication date: January 24, 2008
    Applicants: Kowa Co., Ltd, D. Western Therapeutics Institute, Inc.
    Inventors: Takeshi Ohshima, Hiroyoshi Hidaka, Masami Shiratsuchi, Kazuhiro Onogi, Toshiaki Oda
  • Patent number: 6956132
    Abstract: A process for producing 2-phenylacetophenone derivatives represented by the formula (I): (wherein X is an alkyl group or a haloalkyl group, and Y is a hydrogen atom, a halogen atom or an alkyl group which may be substituted), which comprises reacting a compound represented by the formula (II): (wherein X and Y are as defined above, and R is a hydrogen atom or an alkyl group) with an acid.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: October 18, 2005
    Assignee: Ishihara Sangyo Kaisha. Ltd.
    Inventors: Takeshi Ohshima, Shigeyuki Nishimura, Takayoshi Ando
  • Publication number: 20040176644
    Abstract: A process for producing 2-phenylacetophenone derivatives represented by the formula (I): 1
    Type: Application
    Filed: January 30, 2004
    Publication date: September 9, 2004
    Inventors: Takeshi Ohshima, Shigeyuki Nishimura, Takayoshi Ando
  • Patent number: 6730147
    Abstract: There is provided a surface treating agent for ligneous floorings that makes the surface of a treated floor resistant to slipping and thus is capable of preventing tumbling. The surface treating agent for ligneous floorings contains a drying oil, Japan wax, candelilla wax, and powdery carnauba wax.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: May 4, 2004
    Assignee: Cera Rica Noda Co., Ltd.
    Inventors: Taizo Noda, Daijiro Ohtani, Takeshi Ohshima
  • Publication number: 20020078859
    Abstract: There is provided a surface treating agent for ligneous floorings that makes the surface of a treated floor resistant to slipping and thus is capable of preventing tumbling. The surface treating agent for ligneous floorings contains a drying oil, Japan wax, candelilla wax, and powdery carnauba wax.
    Type: Application
    Filed: December 17, 2001
    Publication date: June 27, 2002
    Inventors: Taizo Noda, Daijiro Ohtani, Takeshi Ohshima
  • Patent number: 6339362
    Abstract: By connecting a grounding conductor pattern directly to a grounding terminal of a field-effect transistor and connecting a series circuit comprising a stabilized resistor and an open-circuit stub having a length equal to quarter of a parallel resonance frequency, undesirable parallel resonance caused by the grounding conductor pattern and the open-circuit stub is suppressed, and a voltage drop in the stabilized resistor is suppressed when a bias voltage is applied to the field-effect transistor. Accordingly, the operation of a microwave amplifier is stabilized.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: January 15, 2002
    Assignee: Mitsubishi Denki Kabushiki Kaisha
    Inventors: Hiromitsu Uchida, Takeshi Ohshima, Yasushi Itoh
  • Patent number: 6337334
    Abstract: The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: [wherein R1 represents a lower alkyl group; each of R2 and R3 represents H, alkyl, or alkoxy; each of R4 and R5 represents H or alkyl; R6 represents alkyl, —OR7, or —NR8R9; and n is a number between 0 and 3 inclusive (wherein each of R7, R8, and R9 represents H, alkyl, aryl, aralkyl, amino, a heterocyclic ring, etc.)], as well as to a medicine containing the derivative or salt as the active ingredient. The present compounds exhibit strong binding inhibitory activity against endothelin having potent vasoconstrictive effect and cell proliferation effect. Therefore, the compounds are effective as remedies for various diseases including circulatory diseases.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: January 8, 2002
    Assignee: Kowa Co., Ltd.
    Inventors: Mitsuteru Hirata, Takeo Deushi, Yoshio Takahashi, Masahiro Tamura, Takeshi Ohshima, Toshiaki Oda, Hiroyuki Sonoki, Masami Shiratsuchi
  • Patent number: 6163040
    Abstract: A thyris a thyristor is provided in which a lifetime of a minority carrier is controlled to improve the trade-off relationship between an ON-state voltage and a turn-off time and attain a high frequency and a low loss. Shielding members formed of metal plates are provided respectively in spaces above a plane on which a cathode electrode is provided and a plane on which an anode electrode is provided.
    Type: Grant
    Filed: March 17, 1997
    Date of Patent: December 19, 2000
    Assignees: Mitsubishi Denki Kabushiki Kaisha, Japan Atomic Energy Reserch Institute
    Inventors: Hajime Akiyama, Kenichi Honda, Yousuke Morita, Masahito Yoshikawa, Takeshi Ohshima
  • Patent number: 6130580
    Abstract: By connecting a grounding conductor pattern directly to a grounding terminal of a field-effect transistor and connecting a series circuit comprising a stabilized resistor and an open-circuit stub having a length equal to quarter of a parallel resonance frequency, undesirable parallel resonance caused by the grounding conductor pattern and the open-circuit stub is suppressed, and a voltage drop in the stabilized resistor is suppressed when a bias voltage is applied to the field-effect transistor. Accordingly, the operation of a microwave amplifier is stabilized.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: October 10, 2000
    Assignee: Mitsubishi Denki Kabushiki Kaisha
    Inventors: Hiromitsu Uchida, Takeshi Ohshima, Yasushi Itoh
  • Patent number: 6008224
    Abstract: The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: ##STR1## [wherein R.sup.1 represents a lower alkyl group; each of R.sup.2 and R.sup.3 represents H, alkyl, or alkoxy; each of R.sup.4 and R.sup.5 represents H or alkyl; R.sup.6 represents alkyl, --OR.sup.7, or --NR.sup.8 R.sup.9 ; and n is a number between 0 and 3 inclusive (wherein each of R.sup.7, R.sup.8, and R.sup.9 represents H, alkyl, aryl, aralkyl, amino, a heterocyclic ring, etc.)], as well as to a medicine containing the derivative or salt as the active ingredient. The present compounds exhibit strong binding inhibitory activity against endothelin having potent vasoconstrictive effect and cell proliferation effect. Therefore, the compounds are effective as remedies for various diseases including circulatory diseases.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: December 28, 1999
    Assignee: Kowa Co., Ltd.
    Inventors: Mitsuteru Hirata, Takeo Deushi, Yoshio Takahashi, Masahiro Tamura, Takeshi Ohshima, Toshiaki Oda, Hiroyuki Sonoki, Masami Shiratsuchi
  • Patent number: 5883092
    Abstract: The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: ##STR1## ?wherein R.sup.1 represents a hydroxyl group, a lower alkoxy group, a phenyloxy group which may have a substituent, an aralkyloxy group which may have a substituent, or --NR.sup.2 R.sup.3 ; X represents an oxygen atom or N--R.sup.4 ; m is 2 or 3; and n is 1 or 2 (wherein each of R.sup.2 and R.sup.3, which are identical to or different from each other, represents a hydrogen atom, a hydroxyl group, a lower alkyl group which may have a substituent, a phenyl group which may have a substituent, an aralkyl group which may have a substituent, or a heterocyclic group which may have a substituent; R.sup.4 represents a lower alkyl group, a phenyl group, a formyl group, or a lower alkoxycarbonyl group)!, as well as to a medicine containing the derivative or salt as the active ingredient.
    Type: Grant
    Filed: March 4, 1998
    Date of Patent: March 16, 1999
    Assignee: Kowa Co., Ltd.
    Inventors: Mitsuteru Hirata, Takeo Deushi, Yoshio Takahashi, Masahiro Tamura, Takeshi Ohshima, Toshiaki Oda, Tetsuya Ishikawa, Hiroyuki Sonoki, Masami Shiratsuchi
  • Patent number: 5436267
    Abstract: A novel N-phenylcarbamate compound or its salt where possible, which is useful as the active ingredient of a biocidal composition for control of harmful organisms, is represented by the following general formula (I): ##STR1## wherein R.sup.1 is unsubstituted or substituted alkyl; R.sup.2 is H, unsubstituted or substituted alkyl, alkenyl, alkynyl or cycloalkyl, or --COX.sup.1 wherein X.sup.1 is unsubstituted or substituted alkyl, alkenyl, alkynyl, cycloalkyl or alkoxy; Z is --CH.sub.2 S--, --SCH.sub.2 --, --CH.sub.2 O--, --OCH.sub.2 --, --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, --C.tbd.C--, --CH.sub.2 SO--, --CH.sub.2 SO.sub.2 --, --CH.sub.2 SCH.sub.2 --, or --CH.sub.2 O--N.dbd.C(R.sup.4)--; R.sup.
    Type: Grant
    Filed: July 11, 1994
    Date of Patent: July 25, 1995
    Assignee: Ishihara Sangyo Kaisha, Ltd.
    Inventors: Terumasa Komyoji, Itaru Shigehara, Norifusa Matsuo, Hiroshi Shimoharada, Takeshi Ohshima, Toshio Akagi, Shigeru Mitani
  • Patent number: 5023336
    Abstract: An imidazole compound is disclosed, which is represented by formula (I): ##STR1## wherein: X represents a --COOT group, in which T represents a hydrogen atom, an alkyl group, a benzyl group, or a phenyl group; or a --CONH.sub.2 group,Y represents a hydrogen atom, a chlorine atom, or a bromine atom,Z represents an alkyl group containing from 2 to 6 carbon atoms, which may be substituted with one or more halogen atoms; or a phenyl group which may be substituted with one or more halogen atoms or alkyl groups, andQ represents a hydrogen atom; an --SO.sub.2 R.sup.1 group, in which R.sup.1 represents an alkyl group, a dialkylamino group, or a phenyl group which may be substituted with one or more alkyl groups; or a --CH(R.sup.2)(R.sup.3) group, in which R.sup.2 represents a hydrogen atom, a methyl group, or an alkoxy group, and R.sup.3 represents an alkoxy group, an --OCH.sub.2 CH.sub.2 Si (CH.sub.
    Type: Grant
    Filed: October 20, 1989
    Date of Patent: June 11, 1991
    Assignee: Ishihara Sangyo Kaisha Ltd.
    Inventors: Itaru Shigehara, Toshio Nakajima, Shigeyuki Nishimura, Takeshi Ohshima