Patents by Inventor Takeshi Ohshima
Takeshi Ohshima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10273916Abstract: An internal combustion engine including an intake passage fuel injection valve for injecting fuel into an intake passage and a cylinder inside fuel injection valve for injecting fuel into a combustion chamber, includes: a fuel pump pressurizing and feeding fuel, which is fed from a fuel tank, to the cylinder inside fuel injection valve; a securing part provided on a cylinder head member of the internal combustion engine to secure the fuel pump; an introducing member having heat conductivity, the introducing member connected to the fuel pump and formed with: a first introducing path for introducing fuel from the fuel tank to the fuel pump; and a second introducing path for introducing fuel from the fuel tank to the intake passage fuel injection valve; and a heat transmitting member transmitting heat between the introducing member and the securing part.Type: GrantFiled: March 29, 2017Date of Patent: April 30, 2019Assignee: MITSUBISHI JIDOSHA KOGYO KABUSHIKI KAISHAInventors: Kenichi Nozu, Tadanori Minoura, Takeshi Ohshima, Genki Kurimoto
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Publication number: 20170284353Abstract: An internal combustion engine including an intake passage fuel injection valve for injecting fuel into an intake passage and a cylinder inside fuel injection valve for injecting fuel into a combustion chamber, includes: a fuel pump pressurizing and feeding fuel, which is fed from a fuel tank, to the cylinder inside fuel injection valve; a securing part provided on a cylinder head member of the internal combustion engine to secure the fuel pump; an introducing member having heat conductivity, the introducing member connected to the fuel pump and formed with: a first introducing path for introducing fuel from the fuel tank to the fuel pump; and a second introducing path for introducing fuel from the fuel tank to the intake passage fuel injection valve; and a heat transmitting member transmitting heat between the introducing member and the securing part.Type: ApplicationFiled: March 29, 2017Publication date: October 5, 2017Applicant: MITSUBISHI JIDOSHA KOGYO KABUSHIKI KAISHAInventors: Kenichi NOZU, Tadanori MINOURA, Takeshi OHSHIMA, Genki KURIMOTO
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Patent number: 8440824Abstract: To provide a method for producing pyrimidine compound useful as an intermediate for agricultural chemicals or pharmaceuticals, which is simple in operation, presents high yield and produces only a small amount of by-products. The method comprises reacting a compound represented by the formula (I) with a compound represented by the formula (II) in the presence of a pyridine compound to produce a compound represented by the formula (III), a compound represented by the formula (IV) or their mixture.Type: GrantFiled: April 16, 2009Date of Patent: May 14, 2013Assignee: Ishihara Sangyo Kaisha, Ltd.Inventors: Shigeo Murai, Ryoji Koto, Hiroshi Yoshizawa, Takeshi Ohshima, Katsuyoshi Murakami, Takao Awazu, Hisayoshi Jonishi, Takayoshi Ando, Tadashi Nakamura, Norio Adachi, Akihiko Isogai
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Patent number: 8338612Abstract: Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with simple operations by using industrially advantageous reaction systems by a process comprising (1) a step of reacting ACTF and DCDNBTF in the presence of an alkali component, a solvent selected from the group consisting of ketones, nitriles, ethers and esters and a sufficient amount of water to substantially dissolve the alkali component, (2) a step of neutralizing or acidifying the reaction mixture with an acid and (3) a step of removing the solvent by distillation from the mixture containing fluazinam as the reaction product and the reaction solvent to precipitate crystals the product.Type: GrantFiled: July 29, 2008Date of Patent: December 25, 2012Assignee: Ishihara Sangyo Kaisha, Ltd.Inventors: Shigeo Murai, Hiroshi Yoshizawa, Takeshi Ohshima, Katsuyoshi Murakami, Takayoshi Ando, Tadashi Nakamura, Norio Adachi, Akihiko Isogai
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Publication number: 20110021774Abstract: To provide a method for producing pyrimidine compound useful as an intermediate for agricultural chemicals or pharmaceuticals, which is simple in operation, presents high yield and produces only a small amount of by-products. The method comprises reacting a compound represented by the formula (I) with a compound represented by the formula (II) in the presence of a pyridine compound to produce a compound represented by the formula (III), a compound represented by the formula (IV) or their mixture.Type: ApplicationFiled: April 16, 2009Publication date: January 27, 2011Applicant: Ishihara Sangyo Kaisha, Ltd.Inventors: Shigeo Murai, Ryoji Koto, Hiroshi Yoshizawa, Takeshi Ohshima, Katsuyoshi Murakami, Takao Awazu, Hisayoshi Jonishi, Takayoshi Ando, Tadashi Nakamura, Norio Adachi, Akihiko Isogai
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Patent number: 7858615Abstract: The present invention is directed to (S)-(?)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared with (S)-(?)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride anhydrous crystals and thus, exhibits excellent chemical stability.Type: GrantFiled: November 29, 2005Date of Patent: December 28, 2010Assignees: Kowa Co., Ltd., D. Western Therapeutics Institute, Inc.Inventors: Takeshi Ohshima, Hiroyoshi Hidaka, Masami Shiratsuchi, Kazuhiro Onogi, Toshiaki Oda
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Publication number: 20100197930Abstract: Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with simple operations by using industrially advantageous reaction systems by a process comprising (1) a step of reacting ACTF and DCDNBTF in the presence of an alkali component, a solvent selected from the group consisting of ketones, nitriles, ethers and esters and a sufficient amount of water to substantially dissolve the alkali component, (2) a step of neutralizing or acidifying the reaction mixture with an acid and (3) a step of removing the solvent by distillation from the mixture containing fluazinam as the reaction product and the reaction solvent to precipitate crystals the product.Type: ApplicationFiled: July 29, 2008Publication date: August 5, 2010Applicant: Ishihara Sangyo Kaisha LtdInventors: Shigeo Murai, Hiroshi Yoshizawa, Takeshi Ohshima, Katsuyoshi Murakami, Takayoshi Ando, Tadashi Nakamura, Norio Adachi, Akihiko Isogai
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Publication number: 20080021018Abstract: The present invention is directed to (S)-(?)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride dihydrate, to a method producing the dihydrate, and to a drug composition containing the dihydrate. The compound of the present invention has less hygroscopicity as compared with (S)-(?)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1,4-homopiperazine hydrochloride anhydrous crystals and thus, exhibits excellent chemical stability.Type: ApplicationFiled: November 29, 2005Publication date: January 24, 2008Applicants: Kowa Co., Ltd, D. Western Therapeutics Institute, Inc.Inventors: Takeshi Ohshima, Hiroyoshi Hidaka, Masami Shiratsuchi, Kazuhiro Onogi, Toshiaki Oda
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Patent number: 6956132Abstract: A process for producing 2-phenylacetophenone derivatives represented by the formula (I): (wherein X is an alkyl group or a haloalkyl group, and Y is a hydrogen atom, a halogen atom or an alkyl group which may be substituted), which comprises reacting a compound represented by the formula (II): (wherein X and Y are as defined above, and R is a hydrogen atom or an alkyl group) with an acid.Type: GrantFiled: July 15, 2002Date of Patent: October 18, 2005Assignee: Ishihara Sangyo Kaisha. Ltd.Inventors: Takeshi Ohshima, Shigeyuki Nishimura, Takayoshi Ando
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Publication number: 20040176644Abstract: A process for producing 2-phenylacetophenone derivatives represented by the formula (I): 1Type: ApplicationFiled: January 30, 2004Publication date: September 9, 2004Inventors: Takeshi Ohshima, Shigeyuki Nishimura, Takayoshi Ando
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Patent number: 6730147Abstract: There is provided a surface treating agent for ligneous floorings that makes the surface of a treated floor resistant to slipping and thus is capable of preventing tumbling. The surface treating agent for ligneous floorings contains a drying oil, Japan wax, candelilla wax, and powdery carnauba wax.Type: GrantFiled: December 17, 2001Date of Patent: May 4, 2004Assignee: Cera Rica Noda Co., Ltd.Inventors: Taizo Noda, Daijiro Ohtani, Takeshi Ohshima
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Publication number: 20020078859Abstract: There is provided a surface treating agent for ligneous floorings that makes the surface of a treated floor resistant to slipping and thus is capable of preventing tumbling. The surface treating agent for ligneous floorings contains a drying oil, Japan wax, candelilla wax, and powdery carnauba wax.Type: ApplicationFiled: December 17, 2001Publication date: June 27, 2002Inventors: Taizo Noda, Daijiro Ohtani, Takeshi Ohshima
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Patent number: 6339362Abstract: By connecting a grounding conductor pattern directly to a grounding terminal of a field-effect transistor and connecting a series circuit comprising a stabilized resistor and an open-circuit stub having a length equal to quarter of a parallel resonance frequency, undesirable parallel resonance caused by the grounding conductor pattern and the open-circuit stub is suppressed, and a voltage drop in the stabilized resistor is suppressed when a bias voltage is applied to the field-effect transistor. Accordingly, the operation of a microwave amplifier is stabilized.Type: GrantFiled: October 6, 2000Date of Patent: January 15, 2002Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Hiromitsu Uchida, Takeshi Ohshima, Yasushi Itoh
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Patent number: 6337334Abstract: The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: [wherein R1 represents a lower alkyl group; each of R2 and R3 represents H, alkyl, or alkoxy; each of R4 and R5 represents H or alkyl; R6 represents alkyl, —OR7, or —NR8R9; and n is a number between 0 and 3 inclusive (wherein each of R7, R8, and R9 represents H, alkyl, aryl, aralkyl, amino, a heterocyclic ring, etc.)], as well as to a medicine containing the derivative or salt as the active ingredient. The present compounds exhibit strong binding inhibitory activity against endothelin having potent vasoconstrictive effect and cell proliferation effect. Therefore, the compounds are effective as remedies for various diseases including circulatory diseases.Type: GrantFiled: November 5, 1999Date of Patent: January 8, 2002Assignee: Kowa Co., Ltd.Inventors: Mitsuteru Hirata, Takeo Deushi, Yoshio Takahashi, Masahiro Tamura, Takeshi Ohshima, Toshiaki Oda, Hiroyuki Sonoki, Masami Shiratsuchi
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Patent number: 6163040Abstract: A thyris a thyristor is provided in which a lifetime of a minority carrier is controlled to improve the trade-off relationship between an ON-state voltage and a turn-off time and attain a high frequency and a low loss. Shielding members formed of metal plates are provided respectively in spaces above a plane on which a cathode electrode is provided and a plane on which an anode electrode is provided.Type: GrantFiled: March 17, 1997Date of Patent: December 19, 2000Assignees: Mitsubishi Denki Kabushiki Kaisha, Japan Atomic Energy Reserch InstituteInventors: Hajime Akiyama, Kenichi Honda, Yousuke Morita, Masahito Yoshikawa, Takeshi Ohshima
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Patent number: 6130580Abstract: By connecting a grounding conductor pattern directly to a grounding terminal of a field-effect transistor and connecting a series circuit comprising a stabilized resistor and an open-circuit stub having a length equal to quarter of a parallel resonance frequency, undesirable parallel resonance caused by the grounding conductor pattern and the open-circuit stub is suppressed, and a voltage drop in the stabilized resistor is suppressed when a bias voltage is applied to the field-effect transistor. Accordingly, the operation of a microwave amplifier is stabilized.Type: GrantFiled: June 15, 1999Date of Patent: October 10, 2000Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Hiromitsu Uchida, Takeshi Ohshima, Yasushi Itoh
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Patent number: 6008224Abstract: The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: ##STR1## [wherein R.sup.1 represents a lower alkyl group; each of R.sup.2 and R.sup.3 represents H, alkyl, or alkoxy; each of R.sup.4 and R.sup.5 represents H or alkyl; R.sup.6 represents alkyl, --OR.sup.7, or --NR.sup.8 R.sup.9 ; and n is a number between 0 and 3 inclusive (wherein each of R.sup.7, R.sup.8, and R.sup.9 represents H, alkyl, aryl, aralkyl, amino, a heterocyclic ring, etc.)], as well as to a medicine containing the derivative or salt as the active ingredient. The present compounds exhibit strong binding inhibitory activity against endothelin having potent vasoconstrictive effect and cell proliferation effect. Therefore, the compounds are effective as remedies for various diseases including circulatory diseases.Type: GrantFiled: June 27, 1997Date of Patent: December 28, 1999Assignee: Kowa Co., Ltd.Inventors: Mitsuteru Hirata, Takeo Deushi, Yoshio Takahashi, Masahiro Tamura, Takeshi Ohshima, Toshiaki Oda, Hiroyuki Sonoki, Masami Shiratsuchi
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Patent number: 5883092Abstract: The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: ##STR1## ?wherein R.sup.1 represents a hydroxyl group, a lower alkoxy group, a phenyloxy group which may have a substituent, an aralkyloxy group which may have a substituent, or --NR.sup.2 R.sup.3 ; X represents an oxygen atom or N--R.sup.4 ; m is 2 or 3; and n is 1 or 2 (wherein each of R.sup.2 and R.sup.3, which are identical to or different from each other, represents a hydrogen atom, a hydroxyl group, a lower alkyl group which may have a substituent, a phenyl group which may have a substituent, an aralkyl group which may have a substituent, or a heterocyclic group which may have a substituent; R.sup.4 represents a lower alkyl group, a phenyl group, a formyl group, or a lower alkoxycarbonyl group)!, as well as to a medicine containing the derivative or salt as the active ingredient.Type: GrantFiled: March 4, 1998Date of Patent: March 16, 1999Assignee: Kowa Co., Ltd.Inventors: Mitsuteru Hirata, Takeo Deushi, Yoshio Takahashi, Masahiro Tamura, Takeshi Ohshima, Toshiaki Oda, Tetsuya Ishikawa, Hiroyuki Sonoki, Masami Shiratsuchi
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Patent number: 5436267Abstract: A novel N-phenylcarbamate compound or its salt where possible, which is useful as the active ingredient of a biocidal composition for control of harmful organisms, is represented by the following general formula (I): ##STR1## wherein R.sup.1 is unsubstituted or substituted alkyl; R.sup.2 is H, unsubstituted or substituted alkyl, alkenyl, alkynyl or cycloalkyl, or --COX.sup.1 wherein X.sup.1 is unsubstituted or substituted alkyl, alkenyl, alkynyl, cycloalkyl or alkoxy; Z is --CH.sub.2 S--, --SCH.sub.2 --, --CH.sub.2 O--, --OCH.sub.2 --, --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, --C.tbd.C--, --CH.sub.2 SO--, --CH.sub.2 SO.sub.2 --, --CH.sub.2 SCH.sub.2 --, or --CH.sub.2 O--N.dbd.C(R.sup.4)--; R.sup.Type: GrantFiled: July 11, 1994Date of Patent: July 25, 1995Assignee: Ishihara Sangyo Kaisha, Ltd.Inventors: Terumasa Komyoji, Itaru Shigehara, Norifusa Matsuo, Hiroshi Shimoharada, Takeshi Ohshima, Toshio Akagi, Shigeru Mitani
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Patent number: 5023336Abstract: An imidazole compound is disclosed, which is represented by formula (I): ##STR1## wherein: X represents a --COOT group, in which T represents a hydrogen atom, an alkyl group, a benzyl group, or a phenyl group; or a --CONH.sub.2 group,Y represents a hydrogen atom, a chlorine atom, or a bromine atom,Z represents an alkyl group containing from 2 to 6 carbon atoms, which may be substituted with one or more halogen atoms; or a phenyl group which may be substituted with one or more halogen atoms or alkyl groups, andQ represents a hydrogen atom; an --SO.sub.2 R.sup.1 group, in which R.sup.1 represents an alkyl group, a dialkylamino group, or a phenyl group which may be substituted with one or more alkyl groups; or a --CH(R.sup.2)(R.sup.3) group, in which R.sup.2 represents a hydrogen atom, a methyl group, or an alkoxy group, and R.sup.3 represents an alkoxy group, an --OCH.sub.2 CH.sub.2 Si (CH.sub.Type: GrantFiled: October 20, 1989Date of Patent: June 11, 1991Assignee: Ishihara Sangyo Kaisha Ltd.Inventors: Itaru Shigehara, Toshio Nakajima, Shigeyuki Nishimura, Takeshi Ohshima