Abstract: A method for manufacturing an additively-manufactured object in which deposition is performed by melting and solidifying a metal depending on three-dimensional shape data of a target shape, includes: acquiring the three-dimensional shape data; creating a deposition plan in which a formation track and a heating condition of the metal are determined; determining a difference between a shape of the additively-manufactured object that thermally contracts by cooling after deposition and a shape of the three-dimensional shape data by an operation; modifying the deposition plan until the difference falls within a predetermined allowable range; and additively manufacturing the additively-manufactured object based on the deposition plan in which the difference falls within the allowable range.

Abstract: The preset disclosure provides a catalyst layer that has a small contact resistance with a gas diffusion layer and excellent gas diffusion properties. The catalyst layer for a fuel cell has a uniform thickness and includes fibrous conductive members and catalyst particles. The fibrous conductive members are inclined relative to a surface direction of the catalyst layer, and a lengthwise direction of the fibrous conductive members, on average, matches a first direction.

Abstract: An information processing method calculates a position of a feature corresponding to a trace in a first coordinate system, calculates a position of the feature corresponding to the trace in a second coordinate system, and calculates a size of a first distribution of the position of the feature corresponding to the trace in the first coordinate system and a size of a second distribution of the position of the feature corresponding to the trace in the second coordinate system. Additionally, the information processing method outputs information indicating that the feature corresponding to the trace is the trace formed on the surface of the workpiece in the machining process, and outputs information indicating that the feature corresponding to the trace is a false detection of the trace in the inspection process.

Abstract: The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.

Abstract: A method for manufacturing a laminated battery is a method for manufacturing a laminated battery in which a plurality of unit battery cells each having a negative-electrode layer, a positive-electrode layer are laminated, and a solid electrolyte layer located between the negative-electrode layer and the positive-electrode layer. The method includes laminating the plurality of unit battery cells and collectively compressing, in a direction of laminating, the plurality of unit cells laminated in the laminating. In the laminating, the plurality of unit battery cells are laminated in such an arrangement that two unit battery cells located at both ends in the direction of laminating are both lower in degree of compression than a unit battery cell located between the two unit battery cells.

Abstract: The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.

Abstract: A prophylactic or therapeutic agent for spinal muscular atrophy according to the present invention includes a compound represented by the formula (I) or a salt thereof: wherein: W1, W2, and W3 are each independently selected from the group consisting of C—R2, C—R3, C—Rc, and C—Rd, and are defined by one of the followings (i) to (iv): (i) when W3 is C—R2, then W1 is C—R3, W2 is C—Rc or N, and R1 is a hydrogen atom; (ii) when W3 is C—R3, then W1 is C—R2, W2 is C—Rc or N, and R1 is a hydrogen atom, C1-8 alkyl, or C1-8 alkoxy; (iii) when W1 is C—R2, then W2 is C—Rc or N, W3 is C—Rd, and R1 is an aliphatic heterocycle containing one or more nitrogen atoms, the aliphatic heterocycle being optionally substituted with a non-aromatic substituent; and (iv) when W2 is C—R2, W1 is C—Rc, W3 is C—Rd, and R1 is an aliphatic heterocycle containing one or more nitrogen atoms, the aliphatic heterocycle being optionally substituted with a non-aromatic substituent; R2 is a 6- or more membered aromatic ring optionally s

Abstract: The present technology provides a technology that liquid in round-bottom vessels is efficiently agitated. There is provided a vessel rack at least including a holder having a plurality of through-holes into which round-bottom vessels each having a closed-bottom tube shape are inserted, and a support having a plurality of supporting holes that are arranged facing to the through-holes and support bottoms of the round-bottom vessels, the bottoms of the supporting holes each having a bulge such that liquid in the round-bottom vessels forms a vortex at a time of agitation of the liquid. Also, there is provided an agitator of agitating liquid in round-bottom vessels at least including the vessel rack, a mounting unit that mounts the vessel rack, and a rocking unit that rocks the mounting unit, and the like.

Abstract: A microchip is provided, which includes a substrate including a fluid channel structure. The fluid channel structure includes a first fluid introduction channel and a second fluid introduction channel configured to meet so as to allow merging of a first fluid introduced from the first fluid introduction channel and a second fluid introduced from the second fluid introduction channel. A tapered portion is configured to be positioned after merging the first fluid and the second fluid so as to suppress a spiral flow field generated after the merging.

Abstract: An information processing method includes a step of calculating a position of a feature corresponding to a trace in a first coordinate system defined with reference to a field of view of an image, a step of calculating a position of the feature corresponding to the trace in a second coordinate system defined with reference to a position of a workpiece recorded in the image, a step of calculating a size of a first distribution of the position of the feature corresponding to the trace in the first coordinate system and a size of a second distribution of the position of the feature corresponding to the trace in the second coordinate system, and a step of outputting information indicating that the feature corresponding to the trace is the trace formed on the surface of the workpiece in the machining process, when a difference between the size of the first distribution and the size of the second distribution exceeds a first predetermined value, and outputting information indicating that the feature corresponding t

Abstract: A microchip is provided, which includes a substrate including a fluid channel structure. The fluid channel structure includes a first fluid introduction channel and a second fluid introduction channel configured to meet so as to allow merging of a first fluid introduced from the first fluid introduction channel and a second fluid introduced from the second fluid introduction channel. A tapered portion is configured to be positioned after merging the first fluid and the second fluid so as to suppress a spiral flow field generated after the merging.

Abstract: A laminated battery includes a plurality of battery cells which are laminated and a current collecting lead. Each of the plurality of battery cells has a structure in which a positive electrode current collector, a positive electrode active material layer, a solid electrolyte layer, a negative electrode active material layer, and a negative electrode current collector are laminated in this order. The plurality of battery cells include first and second battery cells adjacent to each other. The first battery cell has a surface that faces the second battery cell and includes an exposed surface not in contact with the second battery cell. At least part of the exposed surface does not overlap the second battery cell when viewed from a laminating direction of the battery cells. The current collecting lead is connected to the exposed surface.

Abstract: A laminated battery includes battery cells which are laminated and a current collecting lead. Each of the battery cells has a structure in which a positive electrode current collector, a positive electrode active material layer, a solid electrolyte layer, a negative electrode active material layer, and a negative electrode current collector are laminated in this order. The battery cells include first and second battery cells adjacent to each other. At least the second battery cell has a side surface inclined with respect to a laminating direction of the battery cells. The first battery cell has a surface facing the second battery cell and including an exposed surface not in contact with the second battery cell. At least part of the exposed surface overlaps at least part of the side surface of the second battery cell viewed from the laminating direction. The current collecting lead is connected to the exposed surface.

Abstract: The present invention aims to provide a heterocyclic compound having an IP6K inhibitory action and expected to be useful as a prophylactic or therapeutic agent for—diseases such as cardiac failure, diabetes and the like. A compound represented by the formula (I): wherein each symbol is as defined in the SPECIFICATION, or a salt thereof has an IP6K inhibitory action and is expected to be useful as a prophylactic or therapeutic agent for diseases such as cardiac failure, diabetes and the like.

Abstract: The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.

Abstract: The present invention aims to provide a heterocyclic compound having an IP6K inhibitory action and expected to be useful as a prophylactic or therapeutic agent for—diseases such as cardiac failure, diabetes and the like. A compound represented by the formula (I): wherein each symbol is as defined in the SPECIFICATION, or a salt thereof has an IP6K inhibitory action and is expected to be useful as a prophylactic or therapeutic agent for diseases such as cardiac failure, diabetes and the like.

Abstract: A microchip is provided, which includes a substrate including a fluid channel structure. The fluid channel structure includes a first fluid introduction channel and a second fluid introduction channel configured to meet so as to allow merging of a first fluid introduced from the first fluid introduction channel and a second fluid introduced from the second fluid introduction channel. A tapered portion is configured to be positioned after merging the first fluid and the second fluid so as to suppress a spiral flow field generated after the merging.

Abstract: A microchip is provided, which includes a substrate including a fluid channel structure. The fluid channel structure includes a first fluid introduction channel and a second fluid introduction channel configured to meet so as to allow merging of a first fluid introduced from the first fluid introduction channel and a second fluid introduced from the second fluid introduction channel. A tapered portion is configured to be positioned after merging the first fluid and the second fluid so as to suppress a spiral flow field generated after the merging.