Patents by Inventor Taketoshi Ishii

Taketoshi Ishii has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of Parkinson's disease and enhancement of dopamine signal using PDE 10 inhibitor
    Patent number: 8338420
    Abstract: The present invention relates to a therapeutic or prophylactic method for treating Parkinson's disease by administering an effective amount of a compound having a phosphodiesterase 10 inhibitory activity; and also relates to a pharmaceutical composition for treatment or prophylaxis of Parkinson's disease comprising as an active ingredient a compound having a phosphodiesterase 10 inhibitory activity. Moreover, the present invention relates to a method for enhancing dopamine signal in the brain, which comprises administering an effective amount of a compound having a phosphodiesterase 10 inhibitory activity; and also relates to pharmaceutical composition for enhancing dopamine signal in brain comprising as an active ingredient a compound having a phosphodiesterase 10 inhibitory activity.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: December 25, 2012
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Jun Kotera, Takashi Sasaki, Takeo Kitazawa, Taketoshi Ishii, Hiroshi Morimoto, Harutami Yamada
  • Piperidine compounds
    Patent number: 7619092
    Abstract: The present invention provides a novel piperidine compound of the formula [I]: wherein Ring A represents an optionally substituted benzene ring, Ring B represents an optionally substituted benzene ring, R1 represents an optionally substituted alkyl group, an optionally substituted hydroxyl group, etc., or a group of the formula: (a) wherein R11 and R12 are the same or different, and each represents hydrogen atom, a substituted carbonyl group, a substituted sulfonyl group, an optionally substituted alkyl group, etc., R2 represents hydrogen atom, etc., Z represents oxygen atom or a group represented by —N(R3)—, R3 represents hydrogen atom or an alkyl group, etc., R4 represents hydrogen atom or an alkyl group, etc., or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 29, 2003
    Date of Patent: November 17, 2009
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Masami Takahashi, Tsutomu Miyake, Yasunori Moritani, Hidetoshi Asai, Taketoshi Ishii, Rikako Kono
  • Novel piperidine compound
    Publication number: 20050239829
    Abstract: The present invention provides a novel piperidine compound of the formula [I]: wherein Ring A represents an optionally substituted benzene ring, Ring B represents an optionally substituted benzene ring, R1 represents an optionally substituted alkyl group, an optionally substituted hydroxyl group, etc., or a group of the formula: (a) wherein R11 and R12 are the same or different, and each represents hydrogen atom, a substituted carbonyl group, a substituted sulfonyl group, an optionally substituted alkyl group, etc., R2 represents hydrogen atom, etc., Z represents oxygen atom or a group represented by —N(R3)—, R3 represents hydrogen atom or an alkyl group, etc., R4 represents hydrogen atom or an alkyl group, etc., or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 29, 2003
    Publication date: October 27, 2005
    Applicant: Tanabe Seiyaku Co. Ltd.
    Inventors: Masami Takahashi, Tsutomu Miyake, Yasunori Moritani, Hidetoshi Asai, Taketoshi Ishii, Rikako Kono