Patents by Inventor Taku FUKUZAWA

Taku FUKUZAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-MASP-1 antibodies and methods of use
    Patent number: 11827717
    Abstract: The present invention provides anti-MASP-1 (mannan-binding lectin (MBL)-associated serine protease 1) antibodies and methods of using the same. In some embodiments, an anti-MASP-1 antibody of the invention binds to MASP-1 but does not bind to MASP-3. The invention also provides nucleic acids comprising a nucleotide sequence encoding an anti-MASP-1 antibody of the present invention. The invention further provides pharmaceutical compositions comprising an anti-MASP-1 antibody of the present invention and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: November 28, 2023
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Yoshinao Ruike, Taku Fukuzawa
  • PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OR PREVENTION OF A C5-RELATED DISEASE AND A METHOD FOR TREATING OR PREVENTING A C5-RELATED DISEASE
    Publication number: 20230250162
    Abstract: The present invention relates to pharmaceutical compositions for use in the treatment or prevention of a C5-related disease and methods for treating or preventing a C5-related disease. The present invention further relates to dosages and administrations of anti-C5 antibody or pharmaceutical compositions containing the anti-C5 antibody.
    Type: Application
    Filed: March 10, 2023
    Publication date: August 10, 2023
    Inventors: Kenji SHINOMIYA, Koichiro YONEYAMA, Norihito SHIBAHARA, Yoshinori TSUBOI, Taku FUKUZAWA, Kenta HARAYA, Zenjiro SAMPEI, Katrijn BOGMAN, Jean Eric CHAROIN
  • ANTI-COMPLEMENT COMPONENT ANTIBODIES AND METHODS OF USE
    Publication number: 20210198347
    Abstract: The invention provides anti-complement component antibodies such as anti-C1s antibodies and anti-C1r antibodies, and methods of using the same. The invention also provides pharmaceutical formulations comprising the antibodies, and methods of treating an individual having a complement-mediated disease or disorder comprising administering the antibody to the individual. The binding specificity and C1q displacement function of the anti-C1s antibodies and anti-C1r antibodies are evaluated. Time dependent complement neutralization function and binding to native and truncated C1s or C1r proteins are also shown for the antibodies.
    Type: Application
    Filed: April 12, 2019
    Publication date: July 1, 2021
    Inventors: Taku FUKUZAWA, Kenta HARAYA, Wei Shiong Adrian HO, Noriyuki TAKAHASHI, Masaru MURAOKA
  • ANTI-MASP-1 ANTIBODIES AND METHODS OF USE
    Publication number: 20210115154
    Abstract: The present invention provides anti-MASP-1 (mannan-binding lectin (MBL)-associated serine protease 1) antibodies and methods of using the same. In some embodiments, an anti-MASP-1 antibody of the invention binds to MASP-1 but does not bind to MASP-3. The invention also provides nucleic acids comprising a nucleotide sequence encoding an anti-MASP-1 antibody of the present invention. The invention further provides pharmaceutical compositions comprising an anti-MASP-1 antibody of the present invention and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 2, 2018
    Publication date: April 22, 2021
    Inventors: Yoshinao RUIKE, Taku FUKUZAWA
  • PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OR PREVENTION OF A C5-RELATED DISEASE AND A METHOD FOR TREATING OR PREVENTING A C5-RELATED DISEASE
    Publication number: 20200407432
    Abstract: The present invention relates to pharmaceutical compositions for use in the treatment or prevention of a C5-related disease and methods for treating or preventing a C5-related disease. The present invention further relates to dosages and administrations of anti-C5 antibody or pharmaceutical compositions containing the anti-C5 antibody.
    Type: Application
    Filed: July 14, 2020
    Publication date: December 31, 2020
    Inventors: Kenji SHINOMIYA, Koichiro Yoneyama, Norihito Shibahara, Yoshinori Tsuboi, Taku Fukuzawa, Kenta Haraya, Zenjiro Sampei, Katrijn Bogman, Jean Eric Charoin
  • PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT OR PREVENTION OF A C5-RELATED DISEASE AND A METHOD FOR TREATING OR PREVENTING A C5-RELATED DISEASE
    Publication number: 20190367599
    Abstract: The present invention relates to pharmaceutical compositions for use in the treatment or prevention of a C5-related disease and methods for treating or preventing a C5-related disease. The present invention further relates to dosages and administrations of anti-C5 antibody or pharmaceutical compositions containing the anti-C5 antibody.
    Type: Application
    Filed: January 31, 2018
    Publication date: December 5, 2019
    Inventors: Kenji SHINOMIYA, Koichiro YONEYAMA, Norihito SHIBAHARA, Yoshinori TSUBOI, Taku FUKUZAWA, Kenta HARAYA, Zenjiro SAMPEI, Katrijn BOGMAN, Jean Eric CHAROIN