Patents by Inventor Taku Sakazume
Taku Sakazume has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9360492Abstract: The automatic analyzer includes: a disk having a plurality of holding sections for holding a plurality of containers on the circumference of the disk or on a closed loop that rotationally moves, the disk adapted to move the plurality of containers; a reagent dispensing mechanism for dispensing a reagent into the container on the disk; and a sample dispensing mechanism for dispensing a sample into the container on the disk. The automatic analyzer also includes a container transfer mechanism for mounting the container in the holding sections on the disk. The container transfer mechanism is driven in such a manner that the container can be mounted in the plurality of holding sections on the disk.Type: GrantFiled: May 18, 2011Date of Patent: June 7, 2016Assignee: Hitachi High-Technologies CorporationInventors: Katsuaki Takahashi, Taku Sakazume, Yukinori Sakashita
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Publication number: 20160139164Abstract: A cartridge for dispensing a fluid is presented. The cartridge comprises a reservoir chamber for receiving the fluid. The reservoir chamber has a fluid outlet. The cartridge further comprises a controllable dispenser component for dispensing a dispensing volume of the fluid from the reservoir chamber. The dispenser component is connected to the fluid outlet of the reservoir. The cartridge further comprises a single compressible fluid pump with a single elastic pumping element and a conduit extending from the fluid pump towards the fluid outlet. The fluid pump discharges a mixing volume of the fluid from the conduit into the reservoir chamber upon compression of the elastic pumping element. The mixing volume depends on the degree of compression of the elastic pumping element. The fluid pump sucks in the mixing volume from the reservoir into the conduit upon decompression of the elastic pumping element.Type: ApplicationFiled: January 26, 2016Publication date: May 19, 2016Inventors: Thorsten Brueckner, Christoph Boehm, Juergen Spinke, Terumi Tamura, Taku Sakazume, Kyoko Imai
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Publication number: 20160126058Abstract: An electron microscope has a large depth of focus in comparison with an optical microscope. Thus, information is superimposed on one image in the direction of depth. Therefore, it is necessary to accurately specify the three-dimensional position and density of a structure in a specimen so as to observe the three-dimensional structure of the interior of the specimen by using the electron microscope. Furthermore, a specimen that is observed with the optical microscope on a slide glass is not put into a TEM device of the related art. Thus, performing three-dimensional internal structure observation with the electron microscope on a location that is observed with the optical microscope requires very cumbersome preparation of the specimen.Type: ApplicationFiled: March 12, 2014Publication date: May 5, 2016Inventors: Yusuke OMINAMI, Taku SAKAZUME, Sukehiro ITO
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Publication number: 20160097765Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.Type: ApplicationFiled: December 14, 2015Publication date: April 7, 2016Inventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Kenichi Takahashi
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Publication number: 20160084827Abstract: Stepped portions of a flow channel are reduced by completely fixing the channel that extends to the measuring unit, and reducing connections in the channel, thereby to suppress a disturbance in the flow of the liquid suctioned into the measuring unit. A means is provided so that the reaction solution and reagent suctioned will move towards the channel through which the liquids are suctioned.Type: ApplicationFiled: December 7, 2015Publication date: March 24, 2016Inventors: Susumu SAKAIRI, Taku SAKAZUME, Katsuaki TAKAHASHI
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Publication number: 20160077035Abstract: Provided are an electrode, an electrolysis cell, and an electrochemical analyzer that improve the long-term stability of analysis data. A working electrode, a counter electrode, and reference electrode are disposed in an electrolysis cell. The working electrode is obtained by forming a lead wire in a composite material having platinum or a platinum alloy as a base material, in which a metal oxide is dispersed, or in a laminated material obtained by laminating a valve metal and platinum such that the cross sectional crystal texture in the thickness direction of the platinum is formed in layers and the thickness of each layer of the platinum is 5 micrometers or less. The metal oxide is selected from among zirconium oxide, tantalum oxide, and niobium oxide, and the metal oxide content of the platinum or the platinum alloy is 0.005 to 1 wt % in terms of the zirconium, tantalum, or niobium metal.Type: ApplicationFiled: December 1, 2015Publication date: March 17, 2016Applicant: Hitachi High-Technologies CorporationInventors: Hiroshi KANEMOTO, Hauro AKAHOSHI, So OGUCHI, Kenta IMAI, Taku SAKAZUME, Hiroshi YOSHIDA
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Patent number: 9255937Abstract: Provided is an automatic analyzer that includes a suction nozzle, a detection container, and a detector. The suction nozzle suctions a sample and a solution used for the detection of the sample. The suctioned sample and the solution are supplied to the detection container. The detector detects a signal from the sample. In addition, a vessel for the sample and a container for the solution are disposed below the detection container.Type: GrantFiled: July 20, 2011Date of Patent: February 9, 2016Assignee: HITACHI HIGH TECHNOLOGIES CORPORATIONInventors: Yukinori Sakashita, Katsuaki Takahashi, Yoshihiro Yamashita, Taku Sakazume
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Publication number: 20160025659Abstract: The purpose of the present invention is to eliminate the effort in placement and extraction of samples in observations using transmitted charged particles. A charged particle beam device (601) is characterized by having: a charged particle optical lens tube that irradiates a sample (6) with a primary charged particle beam; a sample stage on which a light emitting member (500) that emits light because of charged particles that have come by transmission internally in the sample (6) or scattering therefrom or a sample platform (600) having the light emitting member (500) is attachably and detachably disposed; and a detector (503) that detects the light emitted by the light emitting member.Type: ApplicationFiled: January 22, 2014Publication date: January 28, 2016Inventors: Yusuke OMINAMI, Mitsugu SATO, Kenko UCHIDA, Sadamitsu ASO, Taku SAKAZUME, Hideo MORISHITA, Sukehiro ITO, Takashi OHSHIMA
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Patent number: 9244088Abstract: Stepped portions of a flow channel are reduced by completely fixing the channel that extends to the measuring unit, and reducing connections in the channel, thereby to suppress a disturbance in the flow of the liquid suctioned into the measuring unit. A means is provided so that the reaction solution and reagent suctioned will move towards the channel through which the liquids are suctioned.Type: GrantFiled: May 30, 2014Date of Patent: January 26, 2016Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Susumu Sakairi, Taku Sakazume, Katsuaki Takahashi
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Patent number: 9234861Abstract: Provided are an electrode, an electrolysis cell, and an electrochemical analyzer that improve the long-term stability of analysis data. A working electrode, a counter electrode, and reference electrode are disposed in an electrolysis cell. The working electrode is obtained by forming a lead wire in a composite material having platinum or a platinum alloy as a base material, in which a metal oxide is dispersed, or in a laminated material obtained by laminating a valve metal and platinum such that the cross sectional crystal texture in the thickness direction of the platinum is formed in layers and the thickness of each layer of the platinum is 5 micrometers or less. The metal oxide is selected from among zirconium oxide, tantalum oxide, and niobium oxide, and the metal oxide content of the platinum or the platinum alloy is 0.005 to 1 wt % in terms of the zirconium, tantalum, or niobium metal.Type: GrantFiled: December 6, 2011Date of Patent: January 12, 2016Assignee: Hitachi High-Technologies CorporationInventors: Hiroshi Kanemoto, Haruo Akahoshi, So Oguchi, Kenta Imai, Taku Sakazume, Hiroshi Yoshida
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Patent number: 8999240Abstract: An automatic analyzer and an automatic analyzing system to identify samples and reagents used in the analyzer and members used in measurement of at least two objects in common: system reagents or buffer solution; sensor parts; probes; nozzles; chips; dispensing cups; tubes; ISE electrodes; detectors; deionized water; and waste, and to unify management of identification information thereof and a measurement result.Type: GrantFiled: July 11, 2012Date of Patent: April 7, 2015Assignee: Hitachi High-Technologies CorporationInventors: Noriko Maeda, Kyoko Imai, Taku Sakazume, Yukie Tokiwa, Kantaro Suzuki
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Publication number: 20150056098Abstract: A problem of a sample analysis device that uses magnetic particles is the difficulty in uniformly capturing magnetic particles, specifically the poor uniformity in the vicinity of channel side walls. This causes poor analysis accuracy and reproducibility. The present invention is intended to provide a means to uniformly capture magnetic particles in the vicinity of channel side walls. Specifically, the present invention provides an analysis device that includes a detection channel with an inlet and an outlet through which a sample liquid containing a specific substance and magnetic particles is flowed in and out of the channel, and magnetic field generating means capable of varying the magnitude of the magnetic field in a predetermined region of the detection channel. The width of the magnet in the detector is greater than the channel width. The detector can improve the analysis accuracy and reproducibility of the analysis device.Type: ApplicationFiled: December 14, 2012Publication date: February 26, 2015Inventors: Toru Inaba, Shinya Matsuoka, Taku Sakazume, Yoshihiro Yamashita, Masafumi Shimada
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Patent number: 8916096Abstract: According to an embodiment of the disclosure, the analyzer includes a reagent driving disk that accommodates a reagent configured for analysis and that transports the reagent to a desired position, and a fixed disk that has a reagent stand-by position in which to make a reagent container containing the reagent, temporarily stand by, and a magnetic particles stirring position for stirring magnetic particles. A portion of the reagent stand-by position is constituted by a loading system. A reagent container moving unit moves reagent containers containing the reagent, between the reagent driving unit and the fixed disk, according to analytical request status. Providing in a part of the fixed disk the loading system constructed so that reagent containers containing the reagent can be mounted therein during operation enables changing of reagent containers, irrespective of an operational status of the reagent driving disk, and the system to having cold-storage functionality.Type: GrantFiled: September 14, 2012Date of Patent: December 23, 2014Assignee: Hitachi High-Technologies CorporationInventors: Yukinori Sakashita, Katsuaki Takahashi, Susumu Sakairi, Taku Sakazume, Yoshihiro Yamashita
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Publication number: 20140271359Abstract: Stepped portions of a flow channel are reduced by completely fixing the channel that extends to the measuring unit, and reducing connections in the channel, thereby to suppress a disturbance in the flow of the liquid suctioned into the measuring unit. A means is provided so that the reaction solution and reagent suctioned will move towards the channel through which the liquids are suctioned.Type: ApplicationFiled: May 30, 2014Publication date: September 18, 2014Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Susumu SAKAIRI, Taku SAKAZUME, Katsuaki TAKAHASHI
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Patent number: 8802032Abstract: This invention provides an analyzer that has a liquid dispense pipette dispensing liquids with higher accuracy and precision at higher speeds. The analyzer includes a drive mechanism having a stepping motor as a power source. The drive mechanism transmits power from a rotation output shaft of the stepping motor to a moving unit for executing a target motion via at least one power transmission unit. The amount of idling of the moving unit stemming from the stepping motor getting driven in reverse is calculated from the amount of movement of the moving unit, from the amount of pulses fed to the stepping motor, and from the amount of remaining pulses so as to perform motion control of the drive mechanism accordingly.Type: GrantFiled: January 30, 2012Date of Patent: August 12, 2014Assignee: Hitachi High-Technologies CorporationInventors: Yoshihiro Yamashita, Shinya Matsuoka, Taku Sakazume, Yukinori Sakashita
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Patent number: 8753572Abstract: Stepped portions of a flow channel are reduced by completely fixing the channel that extends to the measuring unit, and reducing connections in the channel, thereby to suppress a disturbance in the flow of the liquid suctioned into the measuring unit. A means is provided so that the reaction solution and reagent suctioned will move towards the channel through which the liquids are suctioned.Type: GrantFiled: January 18, 2010Date of Patent: June 17, 2014Assignee: Hitachi High-Technologies CorporationInventors: Susumu Sakairi, Taku Sakazume, Katsuaki Takahashi
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Publication number: 20140030167Abstract: This invention provides an analyzer that has a liquid dispense pipette dispensing liquids with higher accuracy and precision at higher speeds. The analyzer includes a drive mechanism having a stepping motor as a power source. The drive mechanism transmits power from a rotation output shaft of the stepping motor to a moving unit for executing a target motion via at least one power transmission unit. The amount of idling of the moving unit stemming from the stepping motor getting driven in reverse is calculated from the amount of movement of the moving unit, from the amount of pulses fed to the stepping motor, and from the amount of remaining pulses so as to perform motion control of the drive mechanism accordingly.Type: ApplicationFiled: January 30, 2012Publication date: January 30, 2014Inventors: Yoshihiro Yamashita, Shinya Matsuoka, Taku Sakazume, Yukinori Sakashita
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Patent number: 8628720Abstract: Photomultiplier tubes differ in performance between individual products, and deteriorate over time. To appropriately use a nonlinear calibration curve, it is desirable that changes in signal level be strictly equalized. This invention includes means for, prior to sensitivity adjustment of a photomultiplier tube by application of high voltages, measuring a same sample under a plurality of high-voltage conditions, determining, from linear relationships between logarithms of each high voltage and those of signal levels, an optimal voltage for a measuring operation of predetermined order of execution in the plurality of measuring operations, and recording identification information for identifying each linear relationship; the invention assessing a healthiness level of the photomultiplier tube by assessing the linear relationship.Type: GrantFiled: January 13, 2010Date of Patent: January 14, 2014Assignee: Hitachi High-Technologies CorporationInventors: Taku Sakazume, Kantaro Suzuki
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Publication number: 20130304425Abstract: An automatic analyzer and an automatic analyzing system to identify samples and reagents used in the analyzer and members used in measurement of at least two objects in common: system reagents or buffer solution; sensor parts; probes; nozzles; chips; dispensing cups; tubes; ISE electrodes; detectors; deionized water; and waste, and to unify management of identification information thereof and a measurement result.Type: ApplicationFiled: July 15, 2013Publication date: November 14, 2013Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Noriko MAEDA, Kyoko IMAI, Taku SAKAZUME, Yukie TOKIWA, Kantaro SUZUKI
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Publication number: 20130248378Abstract: Provided are an electrode, an electrolysis cell, and an electrochemical analyzer that improve the long-term stability of analysis data. A working electrode, a counter electrode, and reference electrode are disposed in an electrolysis cell. The working electrode is obtained by forming a lead wire in a composite material having platinum or a platinum alloy as a base material, in which a metal oxide is dispersed, or in a laminated material obtained by laminating a valve metal and platinum such that the cross sectional crystal texture in the thickness direction of the platinum is formed in layers and the thickness of each layer of the platinum is 5 micrometers or less. The metal oxide is selected from among zirconium oxide, tantalum oxide, and niobium oxide, and the metal oxide content of the platinum or the platinum alloy is 0.005 to 1 wt % in terms of the zirconium, tantalum, or niobium metal.Type: ApplicationFiled: December 6, 2011Publication date: September 26, 2013Inventors: Hiroshi Kanemoto, Haruo Akahoshi, So Oguchi, Kenta Imai, Taku Sakazume, Hiroshi Yoshida