Patents by Inventor Takuji Hashizume

Takuji Hashizume has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3'-hydroxybenzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same
    Patent number: 4983602
    Abstract: A rifamycin derivative having the formula (I): ##STR1## wherein A is a group having the formula: ##STR2## in which R.sup.1 is an alkyl group having 4 or 5 carbon atoms or an alkenyl group having 3 to 5 carbon atoms, or a group having the formula: in which n is 3 or 4; or a pharmaceutically acceptable salt thereof. The rifamycin derivative (I) exhibits a strong antibacterial activity against Gram-positive bacteria and acid-fast bacteria, and also exhibits a strong antibacterial activity against tubercle bacilli.
    Type: Grant
    Filed: September 14, 1989
    Date of Patent: January 8, 1991
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Takehiko Yamane, Takuji Hashizume, Katsuji Yamashita, Kazunori Hosoe, Fumiyuki Kuze, Kiyoshi Watanabe
  • Substituted benzoxazinorifamycin derivative and antibacterial agent containing the same
    Patent number: 4965261
    Abstract: A rifamycin derivative having the formula (I): ##STR1## wherein R.sup.1 is hydrogen atom, methyl group or ethyl group, R.sup.2 is an alkyl group having 1 to 4 carbon atoms, and A is a group having the formula: ##STR2## in which n is an integer of 3 to 5, or group having the formula: ##STR3## in which R.sup.3 is a alkyl group having 1 to 5 carbon atoms; or a salt thereof. The rifamycin derivative (I) exhibits a strong antibacterial activity against Gram-positive bacteria and acid-fast bacteria, and also exhibits a strong antibacterial activity against tubercle bacilli.
    Type: Grant
    Filed: March 16, 1989
    Date of Patent: October 23, 1990
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Fumihiko Kanoo, Takehiko Yamane, Hideo Kondo, Takuji Hashizume, Katsuji Yamashita, Kazunori Hosoe, Fumiyuki Kuze, Kiyoshi Watanabe
  • Benzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same
    Patent number: 4690919
    Abstract: A novel rifamycin derivative having the general formula (I): ##STR1## or salts thereof, a process for preparing the same and antibacterial agents containing the same as an effective component.The rifamycin derivative of the present invention having the general formula (I) shows a strong antibacterial activity against the Gram-positive bacteria and the acid-fast bacteria.
    Type: Grant
    Filed: February 5, 1986
    Date of Patent: September 1, 1987
    Assignee: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Takehiko Yamane, Takuji Hashizume, Katsuji Yamashita, Kiyoshi Watanabe