Abstract: An acquisition unit acquires pieces of information including information related to a vehicle, information related to the environment inside and outside the vehicle, and information related to a driver on board the vehicle. A determination unit determines priorities of the pieces of information acquired by the acquisition unit on the basis of a service or the like used by the driver among services or the likes provided using information accumulated in a server device. A selection unit selects a piece of information to be transmitted to the server device from among the pieces of information acquired by the acquisition unit on the basis of the priorities determined by the determination unit. A communication unit transmits the piece of information selected by the selection unit to the server device.

Abstract: Included are: a surrounding situation acquiring unit that acquires surrounding situation information regarding a situation around a control target apparatus; a control amount inferring unit that infers a control amount of the control target apparatus on the basis of the surrounding situation information and acquires attention-paid region information regarding an attention-paid region in the surrounding situation information used when the control amount is inferred; a target detecting unit that detects a position of a target present around the control target apparatus on the basis of the surrounding situation information acquired by the surrounding situation acquiring unit; and a reliability determining unit that determines reliability of the control amount inferred by the control amount inferring unit on the basis of the attention-paid region information acquired by the control amount inferring unit and target position information regarding the position of the target detected by the target detecting unit.

Abstract: Presented herein, in certain aspects, are conjugates capable of binding phosphatidylserine (PS) and toll-like receptors (TLRs), and their uses for the treatment of selected diseases and disorders, such as cancer.

Abstract: A compound of formula (I) given below or a pharmaceutically acceptable salt of the compound is useful as an IDO/TDO inhibitor.

Abstract: A compound of formula (I) given below or a pharmaceutically acceptable salt of the compound is useful as an IDO/TDO inhibitor.

Abstract: An ophthalmologic apparatus includes a two-dimensional scanning optical system, a refractive optical system, and a concave mirror. The two-dimensional scanning optical system deflects light from a light source in a first angle range. The refractive optical system deflects the light deflected by the two-dimensional scanning optical system in a second angle range that is wider than the first angle range. The concave mirror includes a reflective surface in at least part of the rotational symmetry surface, and reflects the light emitted from the refractive optical system. The exit-side optical axis of the refractive optical system substantially coincides with the rotational symmetry axis of the rotational symmetry surface. The pupil location in the refractive optical system and the exit focus of the concave mirror are located at optically conjugate positions or in the vicinity of the positions. The exit focus is located at a subject's eye position.

Abstract: This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells. While the invention is not limited to any particular mechanism, the compounds of the invention appear to function at least in part by inhibiting G2 cell cycle checkpoint. Thus, invention compounds can be used to inhibit cell growth alone or be used in combination with a nucleic acid damaging treatment to inhibit cell growth.

Abstract: An ophthalmologic apparatus includes a two-dimensional scanning optical system, a refractive optical system, and a concave mirror. The two-dimensional scanning optical system deflects light from a light source in a first angle range. The refractive optical system deflects the light deflected by the two-dimensional scanning optical system in a second angle range that is wider than the first angle range. The concave mirror includes a reflective surface in at least part of the rotational symmetry surface, and reflects the light emitted from the refractive optical system. The exit-side optical axis of the refractive optical system substantially coincides with the rotational symmetry axis of the rotational symmetry surface. The pupil location in the refractive optical system and the exit focus of the concave mirror are located at optically conjugate positions or in the vicinity of the positions. The exit focus is located at a subject's eye position.

Abstract: This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells. While the invention is not limited to any particular mechanism, the compounds of the invention appear to function at least in part by inhibiting G2 cell cycle checkpoint. Thus, invention compounds can be used to inhibit cell growth alone or be used in combination with a nucleic acid damaging treatment to inhibit cell growth.

Abstract: Novel substituted azole diones are provided that kill cells, suppress cell proliferation, suppress cell growth, abrogate the cell cycle G2 checkpoint and/or cause adaptation to G2 cell cycle arrest. Methods of making and using the invention compounds are provided. The invention provides substituted azole diones to treat cell proliferation disorders. The invention includes the use of substituted azole diones to selectively kill or suppress cancer cells without additional anti-cancer treatment. The invention includes the use of cell cycle G2-checkpoint-abrogating substituted azole diones to selectively sensitize cancer cells to DNA damaging reagents, treatments and/or other types of anti-cancer reagents.

Abstract: Novel substituted azole diones are provided that kill cells, suppress cell proliferation, suppress cell growth, abrogate the cell cycle G2 checkpoint and/or cause adaptation to G2 cell cycle arrest. Methods of making and using the invention compounds are provided. The invention provides substituted azole diones to treat cell proliferation disorders. The invention includes the use of substituted azole diones to selectively kill or suppress cancer cells without additional anti-cancer treatment. The invention includes the use of cell cycle G2-checkpoint-abrogating substituted azole diones to selectively sensitize cancer cells to DNA damaging reagents, treatments and/or other types of anti-cancer reagents.

Abstract: Novel substituted azole diones are provided that kill cells, suppress cell proliferation, suppress cell growth, abrogate the cell cycle G2 checkpoint and/or cause adaptation to G2 cell cycle arrest. Methods of making and using the invention compounds are provided. The invention provides substituted azole diones to treat cell proliferation disorders. The invention includes the use of substituted azole diones to selectively kill or suppress cancer cells without additional anti-cancer treatment. The invention includes the use of cell cycle G2-checkpoint-abrogating substituted azole diones to selectively sensitize cancer cells to DNA damaging reagents, treatments and/or other types of anti-cancer reagents.

Abstract: The present invention provides a method for the prophylaxis or treatment of cancer in a mammal, comprising administering a therapeutically effective amount of CBP501, a prodrug thereof or a pharmaceutically acceptable salt thereof to the mammal, wherein CBP501, a prodrug thereof or a pharmaceutically acceptable salt thereof is administered simultaneously with or before administration of a nucleic acid damaging agent.

Abstract: Novel substituted azole diones are provided that kill cells, suppress cell proliferation, suppress cell growth, abrogate the cell cycle G2 checkpoint and/or cause adaptation to G2 cell cycle arrest. Methods of making and using the invention compounds are provided. The invention provides substituted azole diones to treat cell proliferation disorders. The invention includes the use of substituted azole diones to selectively kill or suppress cancer cells without additional anti-cancer treatment. The invention includes the use of cell cycle G2-checkpoint-abrogating substituted azole diones to selectively sensitize cancer cells to DNA damaging reagents, treatments and/or other types of anti-cancer reagents.

Abstract: A method for surface inspection, comprising the step of projecting at least two laser beams with different wavelengths to a same point to be inspected via a same projecting lens, the step of setting incident angles of the two laser beams so that fluctuations of values of reflectivity of the laser beams are complementary to each other, and the step of detecting reflected scattered light components.

Abstract: A method for surface inspection, comprising the step of projecting at least two laser beams with different wavelengths to a same point to be inspected via a same projecting lens, the step of setting incident angles of the two laser beams so that fluctuations of values of reflectivity of the laser beams are complementary to each other, and the step of detecting reflected scattered light components.

Abstract: An apparatus for surface inspection according to the invention comprises an irradiating optical system for throwing an irradiating light beam from a light source onto the surface of an object of inspection, a light receiving optical system for receiving a scattered light beam reflected from the surface of the object of inspection irradiated by the irradiating optical system, a photosensing portion for forming a surface data signal from the scattered light beam received by the light receiving optical system, a displacement portion for displacing the surface of the object of inspection relative to the irradiating optical system, plus the light receiving optical system, continuously in the main scanning direction and intermittently in the sub-scanning direction, and a foreign matter detecting portion for detecting a foreign matter present on the surface of the object of inspection on the basis of the maximum value level of the surface data signal and obtaining the position, in the sub-scanning direction, of the

Abstract: A rubber-reinforcing polyester fiber composed of a polyester prepared by using 30 to 150 ppm as antimony of an antimony compound and 5 to 60 ppm as germanium of a germanium compound as the polymerization catalyst. The fiber is characterized in that the terminal carboxyl group content is not larger than 25 eq/ton, diethylene glycol content (DEG) is not larger than 1.3% by weight, the intrinsic viscosity (IV) is at least 0.85, the sum (S) of the intermediate elongation and the dry heat shrinkage is lower than 8%, the product between strength and elongation (T.sqroot.E) is at least (2S+5), and the terminal modulus (TM) is not higher than 40 g/d. The polyester fiber is used as a rubber reinforcement.

Abstract: A conjugated fiber having a sheath-core conjugated structure comprising a polyester core component composed mainly of polyethylene terephthalate and a polyamide sheath component composed mainly of polyhexamethylene adipamide, is disclosed, which has excellent mechanical properties such as a high tenacity, a high modulus, and an improved dimensional stability, and an improved adhesion to a rubber, especially a high-temperature adhesion, an improved heat resistance in a rubber, and a high fatigue resistance, and thus is useful as an industrial material. By adopting a high-speed spinning procedure in the fiber preparing process, the peel resistance in the interface of the sheath-core conjugated structure is greatly improved, and the following valuable characteristics not possessed by conventional conjugated yarns can be obtained:(1) Excellent adhesion and high-temperature adhesion comparable to those of a polyamide, which cannot be obtained in a polyester.

Abstract: A laser surveying equipment includes a laser beam luminous section, a suspending reflection member suspended in such a manner as to reflect laser beam radiated from the laser beam luminous section upward and always to direct the optical axis of such reflected light in the perpendicular direction, and a projection lens system adapted to project the laser beam after forming it into a generally parallel flux of light. A rotary reflection member can be rotatably arranged in order to displace by approximately 90 degree an optical path of parallel flux of light obtained from the projection lens system and to scan the parallel flux of light toward a surveying object within a horizontal plane.