Abstract: The invention intends to find out an in-vitro bioassay system capable of ensuring qualities of yokukansan to a higher degree, and provides a bioassay method for yokukansan, comprising competitively reacting labeled ligand and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring binding activity of yokukansan from the amount of the labeled ligand bound, and a bioassay method for yokukansan, comprising reacting labeled GTP and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring receptor-agonist activity of yokukansan from the amount of the labeled GTP bound.

Abstract: The invention intends to find out an in-vitro bioassay system capable of ensuring qualities of yokukansan to a higher degree, and provides a bioassay method for yokukansan, comprising competitively reacting labeled ligand and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring binding activity of yokukansan from the amount of the labeled ligand bound, and a bioassay method for yokukansan, comprising reacting labeled GTP and a test sample containing yokukansan with cells or cell membranes expressing serotonin 1A receptors, and measuring receptor-agonist activity of yokukansan from the amount of the labeled GTP bound.

Abstract: A method for manufacturing alloy powders based on titanium, zirconium and hafnium alloyed with the elements Ni, Cu, Ta, W, Re, Os, and Ir is described in which an oxide of Ti and Zr and Hf is mixed with a metal powder of the elements named and with a reducing agent, and wherein this mixture is heated in a furnace, optionally under a argonate atmosphere or, optionally under hydrogen atmosphere until the reducing reaction begins, the reaction product is leached and then washed and dried, wherein the oxide used has an average grain size of 0.5 to 20 ?m, a specific surface area according to BET of 0.5 20 m2/g and a minimum content of 94 wet.-%. An easy to produce powder, in particular in relation to the ignition point and burning time, is produced.

Abstract: A simple and compact apparatus for removing film from a film magazine includes a film slot opening/closing mechanism which is operated by a film slot opening/closing lever, and a spool driving shaft which is turned by a spool revolving knob. The apparatus further includes a film releasing mechanism. The mechanism has a structure such that a film releasing jig is inserted into a cartridge loaded with a film magazine through the film outlet slot of the cartridge by operating a film releasing jig lever.. The apparatus is used with a film magazine whose spool shaft has a film engagement claw therein. A hole formed in the tail end of film is engaged with the engagement claw. When the film releasing jig is inserted into the cartridge, the film is disengaged from the engagement claw. The film slot opening/closing lever, spool revolving knob, and film releasing jig lever are operated manually.

Abstract: A main lens 500 and an auxiliary lens 550 are selectively loaded on a lens loading section 601 of a lens moving deck 600. The lens moving deck 600 is movable in a certain direction to selectively set the lens loading section 601 at an exposed position and a retracted position adjacent to each other. A lens storage deck 700 is provided adjacent the retracted position to load the main lens 500 thereon for housing.

Abstract: A film-rewinding apparatus to rewind a film from a cartridge into a container which can accommodate the film therein by inserting the film from an opening of the container. The apparatus comprises a cartridge-supporting portion which supports the cartridge; a shielding door driving mechanism for opening and closing the shielding door; a spool-driving mechanism for feeding the film out by driving the spool; a container-supporting portion for supporting the container; an opening and closing driving mechanism for opening and closing the opening; and a film-dismounting mechanism for dismounting the film from the spool. The film-rewinding apparatus can easily perform rewinding by only operating a handle or lever, or by a switching operation, after the cartridge and the intermediate magazine are set and the cover is locked.

Abstract: The present invention relates to novel huperzine A derivatives of formula (II), wherein Y is ##STR1## or R" and Y together form .dbd.CH; R is (C.sub.1 -C.sub.5) alkyl, ##STR2## wherein n is 0 or 1, X is H, (C.sub.1 -C.sub.5) alkyl; (C.sub.1 -C.sub.5) alkyloxy; nitro, halogen, carboxy, alkyloxycarbonyl, hydroxymethyl, hydroxy, amino substituted by bis-(C.sub.1 -C.sub.5) alkyl; --(CH.sub.2).sub.m COOZ, wherein m=0-5, Z is H or (C.sub.1 -C.sub.5) alkyl; --CH.dbd.CH--G, wherein G is phenyl, furanyl, carboxy, alkyloxycarbonyl; and dihydro- or tetrahydro-pyridyl substituted by (C.sub.1 -C.sub.5) alkyl at the nitrogen atom; R' is H, (C.sub.1 -C.sub.5) alkyl, pyridoyl, benzoyl substituted by (C.sub.1 -C.sub.5) alkyloxy; R" is H or (C.sub.1 -C.sub.5) alkyl; processes for their use as acetylcholinesterase inhibitor.

Abstract: Determination is made whether a film stored in a new type of film cartridge is developed or not before the film is processed. A detection sensor detects whether or not there is a nail on an outer wall of the new type of film cartridge to judge whether the film stored in the cartridge is developed or not. Infrared sensors and visible light sensors detect whether or not the film fed from the cartridge under the instruction of a control circuit is developed or not. If both the nail detection sensor and the infrared and visible light sensors give the same result, the result is judged to be correct.

Abstract: A film-rewinding apparatus to rewind a film from a cartridge into a container which can accommodate the film therein by inserting the film from an opening of the container. The apparatus comprises: a cartridge-supporting portion which supports the cartridge; a shielding door driving mechanism for opening and closing the shielding door; a spool-driving mechanism for feeding the film out by driving the spool; a container-supporting portion for supporting the container; and a film-dismounting mechanism for dismounting the film from the spool. The film-rewinding apparatus can easily perform rewinding only by operating a handle or a lever, or by switching operation, after the cartridge and the intermediate magazine are set and the cover is locked.

Abstract: A locking device for use in a processing device for processing photosensitive material such as photographic film has a light-shield cover that can be unlocked without moving a knob plate. The knob plate has an engaging member for locking the light-shield cover. An unlocking mechanism is provided to unlock the light-shield cover without moving the knob plate. The unlocking mechanism has a pushing head, and an unlocking lever having a tip engageable with the engaging member and adapted to be pushed by the pushing head. By moving the unlocking lever with the pushing head until its tip disengages from the engaging member, the engaging member can pass through a cutout, so that the light-shield cover can be unlocked and opened.

Abstract: A sorting apparatus for sorting a plurality of prints produced by a photographic printer. The apparatus includes a movable table for mounting the prints thereon, and a stopper member disposed on an upper surface of the movable table for coming into contact with the prints mounted on the movable table. The movable table is projectable and retractable relative to the stopper member. With a retracting movement of the movable table relative to the stopper member, the prints mounted on the movable table are caused to come into contact with the stopper member and to be dropped off the table to be sorted.

Abstract: A film winding apparatus for winding a film into a cartridge includes a film winding mechanism provided in an apparatus housing for turning a spool housed in the cartridge to wind the film around the spool. The film is inserted through a film inlet located on one side of the apparatus housing and fed toward the film winder. The cartridge loaded on a cartridge mount provided on another side of the apparatus housing is conveyed up to the film winding mechanism, where the cartridge is set in a film loading position. The film winding apparatus thus constructed offers easy operation without any special adjustment or treatment of the film or cartridge, yet featuring single-unit construction and portability.

Abstract: A film rewinder for rewinding film from a film cartridge to an intermediate cartridge. Its driving unit for rotating the film cartridge spool is also used to drive a tool for separating the film trailing end from the film cartridge spool. The film cartridge has a tool guide, so that the entire device is sufficiently compact. The film rewinder has a film cartridge receptacle and a winding unit for winding the film fed from the film cartridge into the intermediate cartridge. A film guide is provided between the receptacle and the winding unit. The spools of the two cartridges are driven by separate motors independently of each other. The tool is an arcuate member adapted to be pivoted in a circular path by the motor for the film cartridge. In order to minimize the length of the film guide and thus to minimize the size of the entire film rewinder, the film guide is provided with a release guide.

Abstract: A film cartridge permits efficient resetting of a film stored in a film container. A cover is mounted on a cartridge body so as to be movable between an open position and a closed position. In the closed position, a film storage space is defined by the cover and the cartridge body. A film inlet/outlet slit communicates with the outside of the film storage space. A mounted in the film storage space are a spool and a guide plate for guiding a film inserted into the film storage space onto the outer periphery of the spool. The guide plate is pivotally supported. A roller is rotatably mounted on the end of the guide plate opposite the outer periphery of the spool. The guide plate is biased by a spring so that the roller is pressed against the spool. A film inserted through the film inlet/outlet into the film storage space is guided into between the spool and the roller by the guide plate. The spool is rotated in this state to wind the film around the spool.

Abstract: The present invention relates to a chromone derivative and an aldose reductase inhibitor comprising said compound as efective component, which is represented by the following formula: ##STR1## wherein R.sub.1 and R.sub.2 each represent a lower alkyl group, etc., R.sub.3 represents an oxygen atom, a sulfur atom, etc., R.sub.7 represents a phenyl group substituted or not substituted, etc., and R represents a hydrogen atom or a lower alkoxy group. The present compounds exhibit superior inhititory action on aldose reductase and are useful for the treatment of various complications of diseases in diabetes, such as cataract, retinopathy, keratopathy, nephropathy, and neuropathy.

Abstract: The present invention relates to a chromone derivative and an aldose reductase inhibitor comprising said compound as efective component, which is represented by the following formula: ##STR1## wherein R.sub.1 and R.sub.2 each represent a lower alkyl group, etc., R.sub.3 represents an oxygen atom, a sulfur atom, etc., R.sub.7 represents a phenyl group substituted or not substituted, etc., and R represents a hydrogen atom or a lower alkoxy group. The present compounds exhibit superior inhititory action on aldose reductase and are useful for the treatment of various complications of diseases in diabetes, such as cataract, retinopathy, keratopathy, nephropathy, and neuropathy.

Abstract: An automatic film developing apparatus for developing a photographic film being guided by a leader, comprising a film separating and forming mechanism for separating the developed film conveyed from the developing section of the apparatus from the leader, and forming the separated portion of the film into a specified shape. The developed film is automatically separated from the leader by the film separating and forming mechanism, and, at the same time, the separated portion is formed in a predetermined shape so as not to be caught in the guide of the negative mask or in a predetermined shape so as to be easily wound up in the cartridge, thereby saving the labor and enhancing the job efficiency.

Abstract: An automatic film developing apparatus comprising a film drawing section for drawing out an exposed film wound in a cartridge, a developing section for developing the exposed film, a film wind-up section for winding up the developed film into the cartridge, and a cartridge conveying section for transferring the cartridge from the film drawing section to the film wind-up section. The cartridge from which the film is drawn out in the film drawing section is conveyed into the film wind-up section by the cartridge conveying section, so that the film can be securely put back into the original cartridge. Therefore, the film is not put into wrong cartridge by mistake. These film processing steps are carried out automatically, and hence the labor in the work is saved.

Abstract: The present invention relates to a chromone derivative of formula (1): ##STR1## (wherein R.sub.1 and R.sub.2 are the same or different and independently represent a hydrogen atom or a lower alkyl group) as well as a synthetic intermediate thereof and an aldose reductase inhibitor comprising said derivative as an active ingredient. The chromone derivatives of the present invention can be easily synthesized, and are useful as aldose reductase inhibitor with an excellent inhibitory action on aldose reductase.

Abstract: An operations condition display system for use in a photographic processing system is disclosed. The display system includes a first communication component provided in an automatic film developing device for transmitting information concerning an operation condition of the film developing device, a second communication component provided in a photographic printing device for receiving the information from the first communication component, and a display component provided in the photographic printing device for displaying the information received by the second communication component.