Patents by Inventor Takuro Tamura

Takuro Tamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6733968
    Abstract: The present invention has an objective of obtaining more accurate data of microarray experiments by correcting an inter-pin spotting amount error caused upon microarray production using a plurality of pins. Upon microarray production, samples are immobilized on a microarray support using all pins as controls for correcting the inter-pin spotting amount errors. After the microarray experiments, luminescent intensities of the samples used as control spots for correcting the inter-pin spotting amount errors are measured and used to obtain correction parameters for the inter-pin spotting amount errors of respective pins. These parameters are used to correct luminescent intensities of other samples.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: May 11, 2004
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Tomoyuki Yamamoto, Takuro Tamura
  • Patent number: 6690461
    Abstract: A method for displaying microarray information by which unknown but useful information is extracted from a mass amount of sample information obtained with microarrays. Luminescent intensity information of sample spots obtained with the microarrays is standardized for each microarray and displayed as a graph as a difference from the standardized luminescent intensity of a sample spot of interest. Accordingly, information can be compared without being influenced by a difference of experiment status between the microarrays or a difference of physical properties between the samples. A three-dimensional graph is displayed by sorting the set of samples and the set of microarrays to which the sample spots belong, under predetermined conditions, and assigning the set of sorted samples and the set of sorted microarrays to X-axis and Y-axis, and the accumulated luminescence intensity to Z-axis.
    Type: Grant
    Filed: March 27, 2001
    Date of Patent: February 10, 2004
    Assignee: Hitachi Software Engineering Co., Ltd.
    Inventors: Takuro Tamura, Jyunji Yoshii, Katsuya Mizuno
  • Publication number: 20030069701
    Abstract: Where a DNA chip corresponding to a bacterium that is a subsequently added identification object is produced, temporal and pecuniary cost is reduced, and even where a probe unique to the DNA sequence of an identification object cannot be designed, precision in identifying DNA comprised in a sample is maximized. First, on designing a probe, a plurality of different probes are prepared to one kind of bacterium. Where some probes come to be not available by addition of bacteria that are new identification objects, identification is carried out using the remaining probes. Where a probe unique to an identification target bacterium cannot be designed, a probability of correct identification is increased by using multiple probes. Moreover, in consideration with a possibility that multiple kinds of bacteria simultaneously exist, a combination of probes that maximizes a probability of correct identification is selected.
    Type: Application
    Filed: May 7, 2002
    Publication date: April 10, 2003
    Inventors: Toshiko Matsumoto, Ryo Nakashige, Yasuyuki Nozaki, Shingo Ueno, Takuro Tamura
  • Patent number: 6533913
    Abstract: An electrophoresis method, comprising simultaneously electrophoresing a test sample containing a plurality of molecules labeled with a plurality of luminescent reagents and a marker sample containing a plurality of molecules with known molecular weights labeled with the same plurality of luminescent reagents.
    Type: Grant
    Filed: December 2, 1999
    Date of Patent: March 18, 2003
    Assignee: Hitachi Software Engineering, Co., Ltd.
    Inventors: Takuro Tamura, Toshimasa Watanabe, Kenji Yamamoto, Toshiaki Ito, Junji Yoshii
  • Publication number: 20030003494
    Abstract: For comparatively displaying the abundances of a large number of biopolymer species as measured in two different samples in an efficient and distinguishable manner, the values measured for biopolymer abundances in the two samples are normalized so that the sum totals of the measured values as calculated for both samples become equal to each other and the biopolymer abundance ratios between both samples are displayed in the form of a line graph, with the ordinate (logarithmic scale axis) denoting the abundance ratio for each biopolymer between both samples and the abscissa denoting the biopolymer species. On the same graph, the sum of abundances of each biopolymer in both samples may also be displayed along the Y axis as a second axis.
    Type: Application
    Filed: June 25, 2002
    Publication date: January 2, 2003
    Inventors: Fumitoshi Ogura, Takuro Tamura, Atsumi Tsujimoto, Azusa Kato
  • Publication number: 20030004939
    Abstract: To provide a search scheduling apparatus which makes it possible to control influence given by a group of spots of nonspecific reaction or errors of the reaction to arrangement and search to arrange and search probe or the like having an objective characteristic among data of experimental results of an experiment using a microarray. If an expression intensity Ep(I) of a probe P(I), which hybridizes with a sample sm(X) as a search condition, that is, an expression intensity Ep(I)t of an objective probe P(I)t, is set and inputted for a desired sample sm(X) that a user wishes to search by an input/output apparatus 10, an arithmetic unit 20 finds out a microarray A(K) satisfying the search conditions based on a record of experimental results accumulated in a data set file apparatus and displays search results on the input/output apparatus 10.
    Type: Application
    Filed: May 23, 2002
    Publication date: January 2, 2003
    Inventors: Daisuke Yamaguchi, Noriyuki Yamamoto, Takuro Tamura
  • Publication number: 20020186226
    Abstract: A method of comparing dendrograms created by different references or algorithms displays individual dendrograms (201, 202) on a screen in an overlapped yet distinguishable manner. The overlapped portions of the dendrograms are displaced vertically or horizontally from one another and indicated by different colors for individual dendrograms. A specified branch and elements hanging therefrom can be highlighted when displayed, such that differences in the manner in which individual elements of the overlapped dendrograms are clustered can be easily recognized.
    Type: Application
    Filed: April 26, 2002
    Publication date: December 12, 2002
    Inventors: Isamu Muto, Shigeru Yatsuzuka, Iwao Yamashita, Takuro Tamura
  • Publication number: 20020184201
    Abstract: Provided is a means capable of high-speed analysis of a large-scale correlation among sequences of biopolymers and reutilization of any analyzed profile. A large-scale profile database 103 is provided with which the correlation among sequences of biopolymers can be analyzed at a high speed, and any profile can be extracted from the profile database.
    Type: Application
    Filed: May 23, 2002
    Publication date: December 5, 2002
    Inventors: Shigeru Yatsuzuka, Isamu Muto, Iwao Yamashita, Takuro Tamura
  • Publication number: 20020158906
    Abstract: Selection of probes is facilitated by effectuating intuitive and efficient discernment of entire constitutions of correlations between base sequences of biopolymers and base sequences of probes.
    Type: Application
    Filed: February 14, 2002
    Publication date: October 31, 2002
    Inventors: Junya Hashida, Takashi Kozuma, Iwao Yamashita, Takuro Tamura
  • Publication number: 20020160401
    Abstract: A method of conducting accurate identification of biological species with a biochip, and a method of effectuating identification of biological species at a level higher than species are provided. Selection of specific probes for multiple biological species is also facilitated. A plurality of partial sequences A, A′; B, B′; and so on, which are specific to respective targets, are selected as probes in a manner that the partial sequences do not overlap one another. In addition, DNA regions I, J, K and L, which are common to some targets, respectively, are also selected as probes. Alternatively, if there is a common base sequence at leaves below a certain node based on a dendrogram of targets, such a base sequence is designed as a probe unique to the node.
    Type: Application
    Filed: June 24, 2002
    Publication date: October 31, 2002
    Inventors: Yasuyuki Nozaki, Shingo Ueno, Ryo Nakashige, Toshiko Matsumoto, Takuro Tamura
  • Publication number: 20020132258
    Abstract: Disclosed is a technology capable of acquiring transverse knowledge beyond specialized fields such as medicine and biology. From a knowledge database for accumulating objects as object values, the objects having phrases including terms used in a medical field and/or a biological field, and accumulating relations between the objects, the relations having values, as relation values, for expressing mutual relations between the objects quantitatively, objects related to a query object are extracted based on the relations between the objects, and the query object and the objects extracted are displayed together with the relations there between.
    Type: Application
    Filed: February 14, 2002
    Publication date: September 19, 2002
    Inventors: Kousaku Okubo, Takuro Tamura, Iwao Yamashita
  • Patent number: 6453243
    Abstract: A method for displaying results of hybridization experiments using a biochip is provided. In the method, a plurality of control spots spotted in each of a plurality of sections defined on a biochip is measured. The measured data are plotted on a graph for each section, and all of the graphs are simultaneously displayed on a single screen in the same arrangement as that of the sections on the biochip. By simultaneously displaying all of the graphs on a single screen, it is possible to skim the whole biochip to find experimental errors. Also, experimental errors can be quantified with respect to the dispersion of control data on the basis of the linearity of the data points and slope angles defined for each data points on a graph.
    Type: Grant
    Filed: June 18, 2001
    Date of Patent: September 17, 2002
    Assignee: Hitachi Software Engineering Co, Ltd.
    Inventors: Tsunehiko Watanabe, Yasuyuki Nozaki, Ryo Nakashige, Takuro Tamura
  • Publication number: 20020049543
    Abstract: The present invention aims at providing a visual display which is useful in roughly understanding the state of groupings and changes, by comparing expression data of genes from two experiments based on expression data of one sample common to both experiments.
    Type: Application
    Filed: March 27, 2001
    Publication date: April 25, 2002
    Inventors: Ryo Nakashige, Yasuyuki Nozaki, Takuro Tamura, Tsunehiko Watanabe
  • Publication number: 20020045181
    Abstract: A method for displaying results of hybridization experiments using a biochip is provided. In the method, a plurality of control spots spotted in each of a plurality of sections defined on a biochip is measured. The measured data are plotted on a graph for each section, and all of the graphs are simultaneously displayed on a single screen in the same arrangement as that of the sections on the biochip. By simultaneously displaying all of the graphs on a single screen, it is possible to skim the whole biochip to find experimental errors. Also, experimental errors can be quantified with respect to the dispersion of control data on the basis of the linearity of the data points and slope angles defined for each data points on a graph.
    Type: Application
    Filed: June 18, 2001
    Publication date: April 18, 2002
    Inventors: Tsunehiko Watanabe, Yasuyuki Nozaki, Ryo Nakashige, Takuro Tamura
  • Publication number: 20020039435
    Abstract: The present invention aims at easy and efficient selection of bands present on a lane.
    Type: Application
    Filed: June 29, 2001
    Publication date: April 4, 2002
    Inventors: Noriyuki Yamamoto, Takuro Tamura, Toshimasa Watanabe
  • Publication number: 20020021299
    Abstract: In a method for verifying the accuracy of hybridization experiments in which a plurality of probe biopolymers are hybridized to sample biopolymers, information concerning the hybridization level for each of the probe biopolymers obtained from the hybridization experiment is displayed together with similarity scores representing the similarities between base sequences of the respective probe biopolymers.
    Type: Application
    Filed: March 14, 2001
    Publication date: February 21, 2002
    Inventors: Takuro Tamura, Noriyuki Yamamoto, Nobuaki Suzuki, Katsuya Mizuno
  • Publication number: 20010034027
    Abstract: The present invention has an objective of obtaining more accurate data of microarray experiments by correcting an inter-pin spotting amount error caused upon microarray production using a plurality of pins.
    Type: Application
    Filed: March 1, 2001
    Publication date: October 25, 2001
    Inventors: Tomoyuki Yamamoto, Takuro Tamura
  • Publication number: 20010016318
    Abstract: The present invention provides methods for extracting similar expression patterns and related biopolymers considering natures that are characteristic of expression data of, for example, genes.
    Type: Application
    Filed: December 14, 2000
    Publication date: August 23, 2001
    Inventors: Tsunehiko Watanabe, Yasuyuki Nozaki, Ryo Nakashige, Takuro Tamura