Abstract: An adsorption fraction of a liquid mixture by an anion exchange resin, wherein the liquid mixture is obtainable by mixing a hot water extract of a mycelium of Tricholoma matsutake FERM BP-7304 with an alkaline solution extract of a mycelial residue obtained when preparing the hot water extract, is disclosed. Further, an immune enhancing agent and an agent for promoting a recovery from stress comprising the above-described novel adsorption fraction as an active ingredient, are disclosed.

Abstract: By extracting hot water-insoluble and ethanol-insoluble components of the fruit body of Agaricus blazei Murill belonging to the genus Agaricus with 5% ammonium oxalate aqueous solution, degrading the extract with hydrochloric acid and then purifying the acid-degraded product through gel permeation and affinity chromatography, there are obtained the antitumor-active substances having a weight-average molecular weight of 38.times.10.sup.4 daltons and a dispersion degree of 2.3, a weight-average molecular weight of 29.times.10.sup.4 daltons and a dispersion degree of 7.3, a weight-average molecular weight of 2.4.times.10.sup.4 daltons and a dispersion degree of 4.1, and a weight-average molecular weight of 2.0.times.10.sup.4 daltons and a dispersion degree of 3.6. These substances exhibit a significant antitumor effect against solid tumor, when determined by gel permeation.

Abstract: A therapeutic agent which is milk collected from a milk animal which has been immunized by a virus or viruses capable of growing in the digestive tract can be used to prevent a disease such as intractable diseases including multiple sclerosis, acute gastroenteritis and viral hepatitis, which are caused by said virus.