Abstract: The present invention provides a medium composition containing a pyruvate dehydrogenase kinase inhibitor for promoting production of a virus carrying a gene of interest, when culturing virus-producing cells into which the gene of interest has been introduced, a medium composition for promoting production of virus or virus-like particles when culturing cells that produce the virus or virus-like particles, and the like.

Abstract: The present invention provides a medium composition for promoting production of a virus carrying a gene of interest, when culturing a virus-producing mammalian cell into which the gene of interest has been introduced, the medium composition containing ?-alanine, a medium composition for culturing a mammalian cell that produces a virus or virus-like particle, the medium composition containing ?-alanine, and the like.

Abstract: An optical apparatus includes a waveguide structure, a grating pattern positioned on a surface of the waveguide structure and including a plurality of protrusion structures, and a respective insert structure positioned in each of the protrusion structures and on the surface of the waveguide structure, which results in a plurality of insert structures. The protrusion structures have a higher refractive index (RI) than the waveguide structure. The insert structures are reflective to an incident light beam. The protrusion structures and the insert structures are configured to redirect the incident light beam into the waveguide structure.

Abstract: A method for producing an objective protein using animal cells as an expression host is provided. The objective protein is produced by culturing animal cells having an objective protein-producing ability under conditions where the phosphoric acid concentration and/or the potassium concentration in the culture medium is increased.

Abstract: The present invention aims to provide a method for dissociating cell aggregates, which are formed in cell culture, particularly in the cell passaging step, more easily and with less damage to cells, a method for culturing cells using said method, and a cell aggregate dissociation agent therefor. The present invention relates to a method for dissociating cell aggregates, including subjecting cell aggregates to a treatment with a water-insoluble metal ion adsorbent.

Abstract: A heat treatment apparatus includes a control device. The control device includes a heat treatment control unit that controls a heat treatment performed on a processing target accommodated in a processing container, according to a process condition, a cleaning control unit that controls a cleaning process on deposits adhering to the processing container due to the heat treatment, a cumulative film thickness specification unit that specifies a value of a cumulative film thickness of the deposits adhering to the processing container, based on the process condition for the heat treatment, and a temperature correction unit that corrects a temperature of the heat treatment based on a temperature correction amount corresponding to the value of the cumulative film thickness and a frequency of the cleaning process.

Abstract: Provided are a method, an agent, or the like for improving the stability of a medium and for improving the productivity of a recombinant protein. Specifically, provided are: a medium containing N-acetylcysteine and L-cysteine; a method for culturing a cell using a medium containing N-acetylcysteine and L-cysteine; a method for producing a recombinant protein using a medium containing N-acetylcysteine and L-cysteine; and a method, agent, or the like for stabilizing a medium containing L-cysteine using N-acetylcysteine.

Abstract: A method for culturing animal cells and related techniques are provided. Animal cells are cultured in the presence of a pea-derived material and/or yeast extract.

Abstract: Provided are a perfusion culture method and the like that are able to improve the productivity in the production of recombinant protein. Specifically, a method for improving recombinant protein production in perfusion culture of an animal cell having a capacity to produce a recombinant protein, the method comprising adding cystine and/or ammonium iron citrate to a cell culture medium, and the like, are provided.

Abstract: A method of monitoring a liquid raw material in a gas supply device, including a raw material storage tank that stores the liquid raw material, a liquid level detector that detects a liquid level of the liquid raw material, a gas inlet provided in the raw material storage tank, a gas outlet provided in the raw material storage tank, and a raw material inlet provided in the raw material storage tank, includes calculating a remaining amount of the liquid raw material based on a usage amount of the raw material and a replenishment amount of the raw material, estimating a detection result of a virtual sensor from the calculated remaining amount of the liquid raw material, and monitoring the liquid raw material based on a detection result of the liquid level detector and the estimated detection result of the virtual sensor.

Abstract: A production management system includes: an injection molding unit producing a molded product; and a control device. The injection molding unit includes: an injection molding machine molding the molded product by injection molding; a determination unit determining whether a number of the molded products to be produced is equivalent to a predetermined unit of production or not; and an operation information transmitting unit transmitting operation information of the injection molding unit when it is determined that the number of the molded products to be produced is equivalent to the predetermined unit of production. The control device includes an operation information receiving unit receiving the operation information transmitted from the operation information transmitting unit.

Abstract: A manufacturing method for a semiconductor device including a first semiconductor element and a second semiconductor element, includes the steps of forming an insulating layer on a first substrate having a first elastic modulus higher than a second elastic modulus, forming a first semiconductor element having a first bonding surface on the insulating layer, forming a second semiconductor element having a second bonding surface on a second substrate having the second elastic modulus, bonding the first bonding surface and the second bonding surface to each other to form a laminate of the first semiconductor element and the second semiconductor element, and removing the first substrate from the laminate.

Abstract: There is provided an injection molding machine management system including an injection molding machine configured to mold a molded article with injection molding, a peripheral device configured to perform a post-process of the injection molding, and a control device communicably coupled to the injection molding machine and the peripheral device. The injection molding machine management system includes a generating section configured to generate a common identifier for each of predetermined production units and transmit the common identifier to the peripheral device. Molding data concerning the injection molding and post-process data concerning the post-process are correlated with the common identifier.

Abstract: A composition for animal cell culture and techniques relating thereto are provided. A composition for animal cell culture, which contains an amino acid source and ?-ketoglutaric acid, and has the following properties: (A) the ?-ketoglutaric acid is a salt of ?-ketoglutaric acid; and/or (B) the amino acid source is free L-cysteine anhydrate is provided.

Abstract: A deposition mask group includes a first deposition mask having two or more first through holes arranged along two different directions, a second deposition mask having two or more second through holes arranged along two different directions and a third deposition mask having two or more third through holes. The first through hole and the second through hole or the third through hole partly overlap when the first deposition mask, the second deposition mask and the third deposition mask are overlapped.

Abstract: Features are extracted from an observed speech signal including at least speech of multiple speakers including a target speaker. A mask is calculated for extracting speech of the target speaker based on the features of the observed speech signal and a speech signal of the target speaker serving as adaptation data of the target speaker. The signal of the speech of the target speaker is calculated from the observed speech signal based on the mask. Speech of the target speaker can be extracted from observed speech that includes speech of multiple speakers.

Abstract: A heat treatment apparatus includes a control device. The control device includes a heat treatment control unit that controls a heat treatment performed on a processing target accommodated in a processing container, according to a process condition, a cleaning control unit that controls a cleaning process on deposits adhering to the processing container due to the heat treatment, a cumulative film thickness specification unit that specifies a value of a cumulative film thickness of the deposits adhering to the processing container, based on the process condition for the heat treatment, and a temperature correction unit that corrects a temperature of the heat treatment based on a temperature correction amount corresponding to the value of the cumulative film thickness and a frequency of the cleaning process.

Abstract: A deposition mask group includes a first deposition mask having two or more first through holes arranged along two different directions, a second deposition mask having two or more second through holes arranged along two different directions and a third deposition mask having two or more third through holes. The first through hole and the second through hole or the third through hole partly overlap when the first deposition mask, the second deposition mask and the third deposition mask are overlapped.

Abstract: A deposition mask group includes a first deposition mask having two or more first through holes arranged along two different directions, a second deposition mask having two or more second through holes arranged along two different directions and a third deposition mask having two or more third through holes. The first through hole and the second through hole or the third through hole partly overlap when the first deposition mask, the second deposition mask and the third deposition mask are overlapped.

Abstract: A deposition mask group includes a first deposition mask having two or more first through holes arranged along two different directions, a second deposition mask having two or more second through holes arranged along two different directions and a third deposition mask having two or more third through holes. The first through hole and the second through hole or the third through hole partly overlap when the first deposition mask, the second deposition mask and the third deposition mask are overlapped.