Patents by Inventor Takuzo Aida

Takuzo Aida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11389550
    Abstract: Provided is a novel nanoparticle, a contrast agent for magnetic resonance imaging containing the same, and a ligand compound used for production of the nanoparticle. The present invention relates to a nanoparticle including: a metal particle containing iron oxide; and a ligand which is bound to a metal atom on a surface of the metal particle and is represented by formula (3): where m is an integer of 1 to 4, and a broken line represents a coordinate bond with a metal atom on the surface of the metal particle.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: July 19, 2022
    Assignees: RIKEN, NATIONAL INSTITUTES FOR QUANTUM SCIENCE AND TECHNOLOGY
    Inventors: Daigo Miyajima, Toshiaki Takeuchi, Seunghyun Sim, Takuzo Aida, Ichio Aoki
  • Publication number: 20220184236
    Abstract: Provided is a novel nanoparticle, a contrast agent for magnetic resonance imaging containing the same, and a zwitterionic ligand compound used in production of the nanoparticle. The contrast agent for MRI of the present invention can be suitably used as a contrast agent for MRI in a medical field. The nanoparticle and the zwitterionic ligand compound of the present invention are applicable to various pharmaceutical compositions and the like, including a contrast agent for MRI, and can be used widely in the fields of pharmaceuticals, biotechnology, and the like, including various diagnosis methods and examination reagents.
    Type: Application
    Filed: December 27, 2019
    Publication date: June 16, 2022
    Inventors: Tsuyoshi Mizutani, Hiroyoshi Yamada, Hiroki Toya, Akihiko Fujikawa, Seiji Yoshimura, Shigetoshi Kikuchi, Daigo Miyajima, Toshiaki Takeuchi, Takuzo Aida, Ichio Aoki
  • Publication number: 20200330617
    Abstract: Provided is a novel nanoparticle, a contrast agent for magnetic resonance imaging containing the same, and a ligand compound used for production of the nanoparticle. The present invention relates to a nanoparticle including: a metal particle containing iron oxide; and a ligand which is bound to a metal atom on a surface of the metal particle and is represented by formula (3): where m is an integer of 1 to 4, and a broken line represents a coordinate bond with a metal atom on the surface of the metal particle.
    Type: Application
    Filed: June 27, 2018
    Publication date: October 22, 2020
    Inventors: Daigo Miyajima, Toshiaki Takeuchi, Seunghyun Sim, Takuzo Aida, Ichio Aoki
  • Publication number: 20200271740
    Abstract: Provided is an orientation agent for NMR spectroscopy containing a nanosheet which is easy to prepare, excellent in handleability, economic efficiency and versatility, and is capable of being stably aligned to the magnetic field. The nanosheet is coated with a compound having a molecular weight of 1,500 or more and containing 35 or more functional groups per molecule, said functional groups being composed of at least one selected from a hydroxy group, an amino group, an amide group, a carbonyl group, a carboxyl group, a sulfo group, a phosphate group, an imidazole group and a guanidine group.
    Type: Application
    Filed: May 22, 2018
    Publication date: August 27, 2020
    Applicants: RIKEN, NATIONAL INSTITUTE FOR MATERIALS SCIENCE
    Inventors: Noriyuki UCHIDA, Yasuhiro ISHIDA, Kento UENO, Zhifang SUN, Qiaochu LI, Yoshiki YAMAGUCHI, Takayoshi SASAKI, Yasuo EBINA, Takuzo AIDA
  • Patent number: 10655000
    Abstract: An organic/inorganic composite hydrogel can be prepared only through mixing at a room temperature and that has high modulus of elasticity and a self-supporting property that allows a shape to be maintained in water, and a method produces the hydrogel. A hydrogel forming composition that is capable of forming a hydrogel having a self-supporting property, includes: a water-soluble organic polymer having an organic acid structure, an organic acid salt structure, or an organic acid anion structure; a silicate salt; a dispersant for the silicate salt; and a compound having or generating divalent or higher valent positive charge; a hydrogel formed of the composition, and a method for producing the hydrogel.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: May 19, 2020
    Assignees: NISSAN CHEMICAL INDUSTRIES, LTD., RIKEN
    Inventors: Yoshihiro Kudo, Taichi Nakazawa, Takuzo Aida, Yasuhiro Ishida, Shingo Tamesue, Masataka Ohtani
  • Patent number: 10252253
    Abstract: In order to provide g-C3N4 capable of being simply and easily handled, a g-C3N4 film is produced by heating, as a starting material, a compound represented by X+mYm?, wherein X+ is a guanidium ion or the like ion, and Ym? is an anion, to vaporize the compound or its reactant, and depositing the compound or the reactant over a surface of a base material heated, the surface carrying negative electric charges or having ? electrons, so that the compound or the reactant is polymerized on the base material to generate g-C3N4.
    Type: Grant
    Filed: December 24, 2013
    Date of Patent: April 9, 2019
    Assignee: RIKEN
    Inventors: Daigo Miyajima, Hiroki Arazoe, Masuki Kawamoto, Kouki Akaike, Yoshiko Koizumi, Takuzo Aida
  • Patent number: 10030155
    Abstract: An ionic liquid can disperse graphene at a high concentration. The ionic liquid can be represented by general formula (1): in which R1 and R5 may be the same or different and each independently represents a substituted or unsubstituted C1-7 linear or branched alkyl group; R2 is represented by formula (2): in which R6 and R7 may be the same or different and each independently represents a C1-4 linear or branched alkylene group, and m represents an integer of 1-5; R3 and R4 may be the same or different and each independently represent a hydrogen atom, substituted or unsubstituted C1-4 linear or branched alkyl group; X? represents a counter ion; and n represents 0-30.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: July 24, 2018
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Takuzo Aida, Chiyoung Park, Saisuwan Ravi, Michio Matsumoto
  • Patent number: 10031241
    Abstract: A radiation dosimetry gel is excellent in heat resistance, and a radiation dosimeter includes the radiation dosimetry gel as a material for measuring a radiation dose. A radiation dosimetry gel includes a water-soluble organic polymer (A) having an organic acid salt structure or an organic acid anion structure, a silicate (B), and a dispersant (C) for the silicate, and a radiation dosimeter includes the radiation dosimetry gel as a material for measuring a radiation dose.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: July 24, 2018
    Assignees: RIKEN, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Takuya Maeyama, Nobuhisa Fukunishi, Kenichi Ishikawa, Yasuhiro Ishida, Takuzo Aida, Kazuaki Fukasaku, Yoshihiro Kudo, Souichi Monma
  • Publication number: 20170350989
    Abstract: A radiation dosimetry gel is excellent in heat resistance, and a radiation dosimeter includes the radiation dosimetry gel as a material for measuring a radiation dose. A radiation dosimetry gel includes a water-soluble organic polymer (A) having an organic acid salt structure or an organic acid anion structure, a silicate (B), and a dispersant (C) for the silicate, and a radiation dosimeter includes the radiation dosimetry gel as a material for measuring a radiation dose.
    Type: Application
    Filed: December 18, 2015
    Publication date: December 7, 2017
    Applicants: RIKEN, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Takuya MAEYAMA, Nobuhisa FUKUNISHI, Kenichi ISHIKAWA, Yasuhiro ISHIDA, Takuzo AIDA, Kazuaki FUKASAKU, Yoshihiro KUDO, Souichi MONMA
  • Patent number: 9611410
    Abstract: An adhesive resin composition includes an expandable sticky polymer having a structure derived from a Meldrum's acid derivative, or a Meldrum's acid derivative represented by the following general formula (1) and an adhesive resin.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: April 4, 2017
    Assignee: MITSUI CHEMICALS TOHCELLO, INC.
    Inventors: Shinichi Usugi, Noboru Kawasaki, Jun Kamada, Takuzo Aida
  • Patent number: 9481771
    Abstract: There is provided a method for bonding together hydrogels by interposing a polyalkylene glycol between the gel surfaces to be bonded together of hydrogels. A method for bonding together hydrogels of the same type or different types, the method including: interposing a polyalkylene glycol between gel surfaces to be bonded together of the hydrogels and joining together the gel surfaces.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: November 1, 2016
    Assignees: RIKEN, NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Shingo Tamesue, Yasuhiro Ishida, Masataka Ohtani, Takuzo Aida, Yoshihiro Kudo, Taichi Nakazawa
  • Publication number: 20160272806
    Abstract: An organic/inorganic composite hydrogel can be prepared only through mixing at a room temperature and that has high modulus of elasticity and a self-supporting property that allows a shape to be maintained in water, and a method produces the hydrogel. A hydrogel forming composition that is capable of forming a hydrogel having a self-supporting property, includes: a water-soluble organic polymer having an organic acid structure, an organic acid salt structure, or an organic acid anion structure; a silicate salt; a dispersant for the silicate salt; and a compound having or generating divalent or higher valent positive charge; a hydrogel formed of the composition, and a method for producing the hydrogel.
    Type: Application
    Filed: November 10, 2014
    Publication date: September 22, 2016
    Applicants: NISSAN CHEMICAL INDUSTRIES, LTD., RIKEN
    Inventors: Yoshihiro KUDO, Taichi NAKAZAWA, Takuzo AIDA, Yasuhiro ISHIDA, Shingo TAMESUE, Masataka OHTANI
  • Patent number: 9249275
    Abstract: Provided is a hydrogel which includes water as the main component at a high water content and has mechanical strength suitable for practical use and which exhibits high transparency and self-healing and shape-retaining properties. Also provided are both a material for the hydrogel and a novel polyionic dendrimer. A polyionic dendrimer which includes a hydrophilic linear polymer as the core and polyester dendrons attached to both terminals of the linear polymer and in which cationic groups are bonded to the surfaces of the dendrons, the cationic groups being selected from the group consisting of guanidine group, thiourea group, and isothiourea group; a material for a hydrogel, which includes the polyionic dendrimer and clay; and a hydrogel prepared using the material.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: February 2, 2016
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Justin Mynar, Takuzo Aida
  • Patent number: 9243115
    Abstract: There is provided a hydrogel having a self-supporting property that can be produced only through mixing at room temperature, and there is provided a method by which the hydrogel can be manufactured by using industrially easily available raw materials. A hydrogel-forming composition that is capable of forming a hydrogel having a self-supporting property, the hydrogel-forming composition characterized by including: a water-soluble organic polymer having an organic acid salt structure or an organic acid anion structure; a silicate salt; and a dispersant for the silicate salt, having a weight average molecular weight of 200 to 20,000 and having hydrolysis resistance.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: January 26, 2016
    Assignees: NISSAN CHEMICAL INDUSTRIES, LTD., RIKEN
    Inventors: Yoshihiro Kudo, Taichi Nakazawa, Takuzo Aida, Yasuhiro Ishida, Shingo Tamesue, Masataka Ohtani
  • Patent number: 9238718
    Abstract: There is provided a self-supporting hydrogel that can be produced only through mixing at room temperature and that has a high mechanical strength. A hydrogel forming composition that is capable of forming a hydrogel having a self-supporting property, the hydrogel forming composition characterized by including: a water-soluble organic polymer having an organic acid salt structure or an organic acid anion structure; a silicate salt; a dispersant for the silicate salt; and a polyhydric alcohol, and having an extremely high mechanical strength.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: January 19, 2016
    Assignees: NISSAN CHEMICAL INDUSTRIES, LTD., RIKEN
    Inventors: Yoshihiro Kudo, Taichi Nakazawa, Takuzo Aida, Yasuhiro Ishida, Shingo Tamesue, Masataka Ohtani
  • Publication number: 20150352539
    Abstract: In order to provide g-C3N4 capable of being simply and easily handled, a g-C3N4 film is produced by heating, as a starting material, a compound represented by X+mYm?, wherein X+ is a guanidium ion or the like ion, and Ym? is an anion, to vaporize the compound or its reactant, and depositing the compound or the reactant over a surface of a base material heated, the surface carrying negative electric charges or having ? electrons, so that the compound or the reactant is polymerized on the base material to generate g-C3N4.
    Type: Application
    Filed: December 24, 2013
    Publication date: December 10, 2015
    Inventors: Daigo Miyajima, Hiroki Arazoe, Masuki Kawamoto, Kouki Akaike, Yoshiko Koizumi, Takuzo Aida
  • Publication number: 20150274899
    Abstract: There is provided a self-supporting hydrogel that can be produced only through mixing at room temperature and that has a high mechanical strength. A hydrogel forming composition that is capable of forming a hydrogel having a self-supporting property, the hydrogel forming composition characterized by including: a water-soluble organic polymer having an organic acid salt structure or an organic acid anion structure; a silicate salt; a dispersant for the silicate salt; and a polyhydric alcohol, and having an extremely high mechanical strength.
    Type: Application
    Filed: September 18, 2013
    Publication date: October 1, 2015
    Inventors: Yoshihiro Kudo, Taichi Nakazawa, Takuzo Aida, Yasuhiro Ishida, Shingo Tamesue, Masataka Ohtani
  • Publication number: 20150267007
    Abstract: There is provided a hydrogel having a self-supporting property that can be produced only through mixing at room temperature, and there is provided a method by which the hydrogel can be manufactured by using industrially easily available raw materials. A hydrogel-forming composition that is capable of forming a hydrogel having a self-supporting property, the hydrogel-forming composition characterized by including: a water-soluble organic polymer having an organic acid salt structure or an organic acid anion structure; a silicate salt; and a dispersant for the silicate salt, having a weight average molecular weight of 200 to 20,000 and having hydrolysis resistance.
    Type: Application
    Filed: September 18, 2013
    Publication date: September 24, 2015
    Inventors: Yoshihiro Kudo, Taichi Nakazawa, Takuzo Aida, Yasuhiro Ishida, Shingo Tamesue, Masataka Ohtani
  • Publication number: 20150225519
    Abstract: There is provided a method for bonding together hydrogels by interposing a polyalkylene glycol between the gel surfaces to be bonded together of hydrogels. A method for bonding together hydrogels of the same type or different types, the method including: interposing a polyalkylene glycol between gel surfaces to be bonded together of the hydrogels and joining together the gel surfaces.
    Type: Application
    Filed: September 18, 2013
    Publication date: August 13, 2015
    Applicant: RIKEN
    Inventors: Shingo Tamesue, Yasuhiro Ishida, Masataka Ohtani, Takuzo Aida, Yoshihiro Kudo, Taichi Nakazawa
  • Publication number: 20150137027
    Abstract: An ionic liquid can disperse graphene at a high concentration. The ionic liquid can be represented by general formula (1): in which R1 and R5 may be the same or different and each independently represents a substituted or unsubstituted C1-7 linear or branched alkyl group; R2 is represented by formula (2): in which R6 and R7 may be the same or different and each independently represents a C1-4 linear or branched alkylene group, and m represents an integer of 1-5; R3 and R4 may be the same or different and each independently represent a hydrogen atom, substituted or unsubstituted C1-4 linear or branched alkyl group; X? represents a counter ion; and n represents 0-30.
    Type: Application
    Filed: May 14, 2013
    Publication date: May 21, 2015
    Inventors: Takuzo Aida, Chiyoung Park, Saisuwan Ravi, Michio Matsumoto