Patents by Inventor Talal Chatila

Talal Chatila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOTCH4 ANTIBODIES AND USES THEREOF
    Publication number: 20230365712
    Abstract: Provided herein are anti-Notch4 antibodies or antigen binding fragments thereof and their use in the treatment of a disease or disorder associated with increased levels of Notch4.
    Type: Application
    Filed: October 15, 2021
    Publication date: November 16, 2023
    Applicant: The Children's Medical Center Corporation
    Inventors: Talal Chatila, Hani Harb, Mehdi Benamar
  • METHODS AND COMPOSITIONS FOR TREATING CORONAVIRUS INFECTIOUS DISEASE
    Publication number: 20230226095
    Abstract: Described herein are methods and compositions for treating a coronavirus infectious disease, e.g., COVID-19. Aspects of the invention relate to administering to a subject an agent that targets Notch4.
    Type: Application
    Filed: June 11, 2021
    Publication date: July 20, 2023
    Applicant: The Children's Medical Center Corporation
    Inventors: Talal Chatila, Hani Harb, Mehdi Benamar
  • THERAPEUTIC MICROBIOTA FOR THE TREATMENT AND/OR PREVENTION OF DYSBIOSIS
    Publication number: 20220193151
    Abstract: Disclosed are methods and compositions for the prevention and treatment of dysbiosis and associated conditions. In particular, described herein are microbial consortia, including monotherapies or minimal microbial consortia, that can prevent and/or cure dysbiosis and associated conditions. In certain embodiments, the therapy comprises Subdoligranulum variabile. In certain embodiments, the microbial consortia comprise certain members of the taxa Clostridiales, Bacteroidetes, Prevotella, and/or Parabacteroides.
    Type: Application
    Filed: March 26, 2020
    Publication date: June 23, 2022
    Applicants: THE CHILDREN'S MEDICAL CENTER CORPORATION, THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Talal A. CHATILA, Azza ABDEL-GADIR, Emmanuel STEPHEN VICTOR, Rima RACHID, Lynn BRY, Georg GERBER
  • THERAPEUTIC MICROBIOTA FOR THE TREATMENT AND/OR PREVENTION OF FOOD ALLERGY
    Publication number: 20220184150
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Application
    Filed: July 21, 2021
    Publication date: June 16, 2022
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid
  • THERAPEUTIC MICROBIOTA FOR THE TREATMENT AND/OR PREVENTION OF DYSBIOSIS
    Publication number: 20220096566
    Abstract: Disclosed are methods and compositions for the prevention and treatment of dysbiosis and associated conditions. In particular, described herein are compositions of microbial consortia, including minimal microbial consortia, that can prevent and/or cure dysbiosis and associated conditions. In certain embodiments, the microbial consortia comprise certain members of the taxa Clostridiales, Bacteroidetes, Prevotella, and/or Parabacteroides.
    Type: Application
    Filed: November 8, 2019
    Publication date: March 31, 2022
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Lynn BRY, Talal A. CHATILA, Georg GERBER, Azza ABDEL-GADIR, Rima RACHID
  • METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING THE DEVELOPMENT OF FOOD ALLERGIES
    Publication number: 20220000976
    Abstract: Described herein are methods and compositions for treating or preventing a food allergy. Aspects of the invention relates to administering to a subject an agent that induces a regulatory T cell, or population thereof, that expresses ROR yt. Another aspect of the invention relates to administering a fecal matter transplant to a subject having reduced ROR yt-expressing regulatory T cells to treat or prevent a food allergy.
    Type: Application
    Filed: November 8, 2019
    Publication date: January 6, 2022
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. CHATILA, Azza ABDEL-GADIR, Emmanuel Stephen VICTOR, Rima RACHID
  • Therapeutic microbiota for the treatment and/or prevention of food allergy
    Patent number: 10898527
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: January 26, 2021
    Assignees: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid
  • THERAPEUTIC MICROBIOTA FOR THE TREATMENT AND/OR PREVENTION OF FOOD ALLERGY
    Publication number: 20200246398
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Application
    Filed: September 12, 2019
    Publication date: August 6, 2020
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid
  • THERAPEUTIC MICROBIOTA FOR THE TREATMENT AND/OR PREVENTION OF FOOD ALLERGY
    Publication number: 20200222473
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Application
    Filed: March 25, 2020
    Publication date: July 16, 2020
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid
  • Therapeutic microbiota for the treatment and/or prevention of food allergy
    Patent number: 10391131
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: August 27, 2019
    Assignees: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid
  • THERAPEUTIC MICROBIOTA FOR THE TREATMENT AND/OR PREVENTION OF FOOD ALLERGY
    Publication number: 20190192582
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Application
    Filed: March 5, 2019
    Publication date: June 27, 2019
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid
  • Therapeutic microbiota for the treatment and/or prevention of food allergy
    Patent number: 10265349
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: April 23, 2019
    Assignees: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid
  • THERAPEUTIC MICROBIOTA FOR THE TREATMENT AND/OR PREVENTION OF FOOD ALLERGY
    Publication number: 20180117097
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Application
    Filed: November 2, 2017
    Publication date: May 3, 2018
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid
  • THERAPEUTIC MICROBIOTA FOR THE TREATMENT AND/OR PREVENTION OF FOOD ALLERGY
    Publication number: 20180117099
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Application
    Filed: November 2, 2017
    Publication date: May 3, 2018
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid
  • THERAPEUTIC MICROBIOTA FOR THE TREATMENT AND/OR PREVENTION OF FOOD ALLERGY
    Publication number: 20180117098
    Abstract: Disclosed are methods and compositions for the prevention and treatment of food allergy. In particular, described herein are microbial consortia, including minimal microbial consortia, that can prevent and/or cure food allergy. In certain embodiments, the consortia comprise certain members of the taxa Clostridiales and/or Bacteroidetes.
    Type: Application
    Filed: November 2, 2017
    Publication date: May 3, 2018
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal A. Chatila, Lynn Bry, Georg Gerber, Azza Abdel-Gadir, Rima Rachid