Abstract: The rate of degradation of a cooked food product that is maintained at an elevated temperature can be reduced by the use of an encapsulated environment food holder. The encapsulated environment is a small, airtight or semi-airtight containment vessel that retains compositions that escape from a cooked food product over time. The volume of an encapsulated environment is greater than one hundred percent but less than one-thousand percent of the cooked food product volume. By holding single servings or portions of a cooked food product in a small, encapsulated environment palatability or taste of a cooked food product can be extended.

Abstract: An encapsulated environment is an air-circulation-restricted volume, preferably just large enough to hold a single serving of a cooked, protein containing food product. Restricting the air circulation reduces the evaporation of gases and liquids that are normally lost over time. The palatability of a cooked, protein-containing food product is thus maintained by holding the cooked product at a ready-to-eat temperature inside of an encapsulated environment. The encapsulated environment is a compartment configured to hold a single serving of a cooked, protein-containing food product, the compartment being able to be covered or at least partially closed by its use in combination with a sleeve configured to receive a tray into which the compartment is formed.

Abstract: A linear motor activator for a downhole safety valve including a permanent magnet carrier; a plurality of permanent magnets mounted to the permanent magnet carrier; a coil carrier disposed in magnetic field proximity to the permanent magnet carrier; and a plurality of coils mounted to the coil carrier, one of the permanent magnet carrier and the coil carrier being movable relative to the other of the permanent magnet carrier and coil carrier, and being connected to a component of a downhole safety valve and method.

Abstract: Disclosed herein are methods and devices for detection of bacterial HAI. Disclosed methods may be utilized for continuous in vivo monitoring of a potential bacterial infection site and may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of infection. Disclosed methods include utilization of recombinant bacteriophage to deliver to pathogenic bacteria a translatable genetic sequence encoding an optically detectable marker or an enzyme capable of producing an optically detectable marker. Upon detection of the optical signal produced by the marker, medical personnel may be alerted to the presence of pathogenic bacteria at the site of inquiry. Any bacterial causative agent of HAI may be detected according to disclosed methods.

Abstract: The rate of degradation of a cooked food product that is maintained at an elevated temperature can be reduced by the use of an encapsulated environment food holder. The encapsulated environment is a small, airtight or semi-airtight containment vessel that retains compositions that escape from a cooked food product over time. The volume of an encapsulated environment is greater than one hundred percent but less than one-thousand percent of the cooked food product volume. By holding single servings or portions of a cooked food product in a small, encapsulated environment palatability or taste of a cooked food product can be extended.

Abstract: The rate of degradation of a cooked food product that is maintained at an elevated temperature can be reduced by the use of an encapsulated environment food holder. The encapsulated environment is a small, airtight or semi-airtight containment vessel that retains compositions that escape from a cooked food product over time. By holding single servings or portions of a cooked food product in a small, encapsulated environment palatability or taste of a cooked food product can be extended.

Abstract: Disclosed are methods and devices for continuous in vivo monitoring of a potential bacterial infection site. Disclosed devices may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of a hospital acquired infection, thereby providing for earlier intervention. Disclosed methods utilize optical fibers to deliver an excitation signal to an area in which pathogenic bacteria may exist. In the presence of the excitation signal, bacterial pathogens may autofluoresce with a unique spectral signature. Upon generation of a fluorescent emission, an optically detectable emission signal may be transmitted to a detection/analysis device. Analysis of the characteristics of the emission signal produced in response to the excitation signal may be used to determine the presence or concentration of pathogens at the site of inquiry, following which real time information may be transmitted to medical personnel via a wireless transmission system.

Abstract: Disclosed herein are methods and devices for detection of hospital acquired infections. Disclosed methods may be utilized for continuous in vivo monitoring of a potential infection site and may be utilized to alert patients and/or health care providers to changes in the local environment due to the presence of a pathogen at an early stage of infection. Disclosed methods utilize ion sensitive field effect transistors (ISFETs) to detect changes in ionic concentration at the site due to the presence of a pathogen, for instance at a surgical site. When a pathogen is present, the local ionic concentration, and hence the electrical characteristics of an ISFET may change, causing a detectable signal from the ISFET. An ISFET may be associated with a biological material such as an enzyme or a specific binding partner for an expression product of a pathogen to improve detection.

Abstract: Disclosed herein are methods and devices for detection of bacterial HAI. Disclosed methods may be utilized for continuous in vivo monitoring of a potential bacterial infection site and may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of infection. Disclosed methods include utilization of recombinant bacteriophage to deliver to pathogenic bacteria a translatable genetic sequence encoding an optically detectable marker or an enzyme capable of producing an optically detectable marker. Upon detection of the optical signal produced by the marker, medical personnel may be alerted to the presence of pathogenic bacteria at the site of inquiry. Any bacterial causative agent of HAI may be detected according to disclosed methods.

Abstract: Disclosed herein are methods and devices for detection of hospital acquired infections. Disclosed methods may be utilized for continuous in vivo monitoring of a potential infection site or for periodic in vitro monitoring of tissue or fluid from a patient and may be utilized to alert patients and/or health care providers to the presence of a pathogen at an early stage of infection. Disclosed methods utilize fluorophore pairs that optically interact with one another according to Forster resonance energy transfer (FRET) or bioluminescence resonance energy transfer (BRET) mechanism. One member of the pair or a cofactor that interacts with an enzyme to form a member of the pair may be tethered to a device by a substrate that is specific for an enzyme expressed by a targeted pathogen. Upon interaction of the enzyme with the substrate, an optically detectable signal may be altered or initiated, detection of which may then provide information as to the existence of the pathogen at the site.

Abstract: A linear motor activator for a downhole safety valve including a permanent magnet carrier; a plurality of permanent magnets mounted to the permanent magnet carrier; a coil carrier disposed in magnetic field proximity to the permanent magnet carrier; and a plurality of coils mounted to the coil carrier, one of the permanent magnet carrier and the coil carrier being movable relative to the other of the permanent magnet carrier and coil carrier, and being connected to a component of a downhole safety valve and method.

Abstract: Disclosed are methods and devices for continuous in vivo monitoring of a potential bacterial infection site. Disclosed devices may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of a hospital acquired infection, thereby providing for earlier intervention and improved recovery rates from bacterial infection. Disclosed methods utilize optical fibers to deliver an excitation signal to an area in which pathogenic bacteria may exist. In the presence of the excitation signal, bacterial pathogens may autofluoresce with a unique spectral signature. Upon generation of a fluorescent emission, an optically detectable emission signal may be transmitted to a detection/analysis device.

Abstract: Disclosed are methods and devices for continuous in vivo monitoring of a potential infection site. Disclosed devices may be utilized to alert patients and/or health care providers to the presence of a pathogen at an early stage of a hospital acquired infection, thereby providing for earlier intervention and improved recovery rates from bacterial infection. Disclosed methods utilize implantable devices for location at an in vivo site. The implantable device is held in conjunction with an optical fiber that detects and transmits an optically detectable signal generated in the presence of a pathogen. Upon generation of the emission, the optically detectable emission signal may be transmitted to a portable detection/analysis device. Analysis of the characteristics of the emission signal produced may be used to determine the presence or concentration of pathogens at the site of inquiry, following which real time information may be transmitted to medical personnel, for instance via a wireless transmission system.

Abstract: Disclosed herein are methods and devices for detection of hospital acquired infections. Disclosed methods may be utilized for continuous in vivo monitoring of a potential infection site or for periodic in vitro monitoring of tissue or fluid from a patient and may be utilized to alert patients and/or health care providers to the presence of a pathogen at an early stage of infection. Disclosed methods utilize fluorophore pairs that optically interact with one another according to Forster resonance energy transfer (FRET) or bioluminescence resonance energy transfer (BRET) mechanism. One member of the pair or a cofactor that interacts with an enzyme to form a member of the pair may be tethered to a device by a substrate that is specific for an enzyme expressed by a targeted pathogen. Upon interaction of the enzyme with the substrate, an optically detectable signal may be altered or initiated, detection of which may then provide information as to the existence of the pathogen at the site.