Patents by Inventor Tamaki Hoshikawa

Tamaki Hoshikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLY-MORPHOLINO OLIGONUCLEOTIDE GAPMERS
    Publication number: 20240060068
    Abstract: Gapmers or pharmaceutically acceptable salt of the gapmers and methods of making the gapmers are provided. The gapmers include a gap region that contains deoxyribonucleosides linked to each other by phosphorothioate bonds, a 5? wing region positioned at the 5? end of the gap region that contains morpholino monomers linked to each other by phosphorodiamidate bonds, and a 3? wing region positioned at the 3? end of the gap region that contains morpholino monomers linked to each other by phosphorodiamidate bonds. Antisense oligonucleotides are also provided. These antisense oligonucleotides are useful in the preparation of gapmers for inhibition of Tau mRNA transcription.
    Type: Application
    Filed: December 10, 2021
    Publication date: February 22, 2024
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Francis G. Fang, Dae-Shik Kim, Hyeong Wook Choi, Yoshinori Takahashi, Kenji Kikuta, Hikaru Kawashima, Wataru Itano, Toshiki Kurokawa, Tamaki Hoshikawa, Mingde SHAN, John Wang
  • Salt of pentacyclic compound and crystal thereof
    Patent number: 11420980
    Abstract: Salts of the compound represented by formula (I) or crystals thereof have a potential use as drug substances for pharmaceuticals.
    Type: Grant
    Filed: September 15, 2020
    Date of Patent: August 23, 2022
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Kenshi Yoshida, Yoshiaki Ohashi, Tamaki Hoshikawa, Nobuaki Sato, Ikuo Kushida
  • Pentacyclic heterocycles
    Patent number: 11358972
    Abstract: The present invention provides compounds represented by formulas (I) to (XVII) or pharmaceutically acceptable salts thereof:
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: June 14, 2022
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yoshiaki Ohashi, Yoshihiko Norimine, Tamaki Hoshikawa, Yu Yoshida, Yoshihisa Kobayashi, Nobuhiro Sato, Koji Hagiwara, Nobuaki Sato, Shinsuke Hirota, Takaaki Harada, Hikaru Yoshimura
  • Pentacyclic heterocycles
    Patent number: 11267821
    Abstract: The present invention provides compounds represented by formulas (I) to (XVII) or pharmaceutically acceptable salts thereof:
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: March 8, 2022
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yoshiaki Ohashi, Yoshihiko Norimine, Tamaki Hoshikawa, Yu Yoshida, Yoshihisa Kobayashi, Nobuhiro Sato, Koji Hagiwara, Nobuaki Sato, Shinsuke Hirota, Takaaki Harada, Hikaru Yoshimura
  • SALT OF PENTACYCLIC COMPOUND AND CRYSTAL THEREOF
    Publication number: 20210024541
    Abstract: Salts of the compound represented by formula (I) or crystals thereof have a potential use as drug substances for pharmaceuticals.
    Type: Application
    Filed: September 15, 2020
    Publication date: January 28, 2021
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Kenshi Yoshida, Yoshiaki Ohashi, Tamaki Hoshikawa, Nobuaki Sato, Ikuo Kushida
  • PENTACYCLIC HETEROCYCLES
    Publication number: 20200283452
    Abstract: The present invention provides compounds represented by formulas (I) to (XVII) or pharmaceutically acceptable salts thereof:
    Type: Application
    Filed: March 3, 2020
    Publication date: September 10, 2020
    Inventors: Yoshiaki Ohashi, Yoshihiko Norimine, Tamaki Hoshikawa, Yu Yoshida, Yoshihisa Kobayashi, Nobuhiro Sato, Koji Hagiwara, Nobuaki Sato, Shinsuke Hirota, Takaaki Harada, Hikaru Yoshimura
  • Pentacyclic compound
    Patent number: 10239889
    Abstract: The present invention provides compounds represented by formulas (1) to (VI) or pharmaceutically acceptable salts thereof:
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: March 26, 2019
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yoshiaki Ohashi, Yoshihiko Norimine, Tamaki Hoshikawa, Yu Yoshida, Yoshihisa Kobayashi, Nobuhiro Sato, Koji Hagiwara
  • PENTACYCLIC COMPOUND
    Publication number: 20190071452
    Abstract: The present invention provides compounds represented by formulas (I) to (VI) or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: September 5, 2018
    Publication date: March 7, 2019
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Yoshiaki Ohashi, Yoshihiko Norimine, Tamaki Hoshikawa, Yu Yoshida, Yoshihisa Kobayashi, Nobuhiro Sato, Koji Hagiwara