Patents by Inventor Tamar Rubinek

Tamar Rubinek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Klotho protein and related compounds for the treatment and diagnosis of cancer
    Patent number: 10555963
    Abstract: Disclosed is the use of a klotho protein or related compounds (especially KL1 or KL1 analogue) for treatment, and especially treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic agents.
    Type: Grant
    Filed: March 25, 2012
    Date of Patent: February 11, 2020
    Assignee: TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
    Inventors: Ido Wolf, Tamar Rubinek, Bella Kaufman, Lilach Abramovitch
  • Klotho protein and related compounds for the treatment and diagnosis of cancer
    Patent number: 9987326
    Abstract: Disclosed is the use of a klotho protein or related compounds for the diagnosis and treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic agents or hormone-regulating agents.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: June 5, 2018
    Assignees: Tel HaShomer Medical Research Infrastructure and Services Ltd., CEDARS-SINAI MEDICAL CENTER
    Inventors: H. Phillip Koeffler, Ido Wolf, Tamar Rubinek, Bella Kaufman, Lilach Abramovitch
  • Klotho variant polypeptides
    Patent number: 9771567
    Abstract: Disclosed are Klotho variant proteins in which residue Glu414 and/or residue Asp238 is substituted with an amino acid different than L-Glu or L-Asp, respectively, as well as polynucleotides encoding the variant proteins, and the use thereof in therapy, especially for the treatment of cancers, especially breast cancer and pancreatic cancer.
    Type: Grant
    Filed: April 16, 2013
    Date of Patent: September 26, 2017
    Assignee: TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
    Inventors: Ido Wolf, Tamar Rubinek
  • KLOTHO VARIANT POLYPEPTIDES AND USES THEREOF IN THERAPY
    Publication number: 20150079065
    Abstract: Disclosed are Klotho variant proteins in which residue Glu414 and/or residue Asp238 is substituted with an amino acid different than L-Glu or L-Asp, respectively, as well as polynucleotides encoding the variant proteins, and the use thereof in therapy, especially for the treatment of cancers, especially breast cancer and pancreatic cancer.
    Type: Application
    Filed: April 16, 2013
    Publication date: March 19, 2015
    Inventors: Ido Wolf, Tamar Rubinek
  • KLOTHO PROTEIN AND RELATED COMPOUNDS FOR THE TREATMENT AND DIAGNOSIS OF CANCER
    Publication number: 20120178699
    Abstract: Disclosed is the use of a klotho protein or related compounds (especially KL1 or KL1 analogue) for treatment, and especially treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic agents.
    Type: Application
    Filed: March 25, 2012
    Publication date: July 12, 2012
    Applicant: TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
    Inventors: Ido WOLF, Tamar RUBINEK, Bella KAUFMAN, Lilach ABRAMOVITCH
  • Klotho Protein and Related Compounds for the Treatment and Diagnosis of Cancer
    Publication number: 20120172314
    Abstract: Disclosed is the use of a klotho protein or related compounds for the diagnosis and treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic agents or hormone-regulating agents.
    Type: Application
    Filed: March 14, 2012
    Publication date: July 5, 2012
    Applicants: Tel HaShomer Medical Research Infrastructure and Services Ltd., CEDARS-SINAI MEDICAL CENTER
    Inventors: H. Phillip Koeffler, Ido Wolf, Tamar Rubinek, Bella Kaufman, Lilach Abramovitch
  • METHODS AND KITS FOR DETERMINING PREDISPOSITION TO CANCER
    Publication number: 20120014927
    Abstract: Provided are methods and kits for determining predisposition to cancer by determining the presence or absence in a heterozygote form of the KLOTHO functional variant. Also provided are methods of designing treatment and treating cancer based on the increased predisposition to the cancer, and to determine the prognosis of a subject diagnosed with cancer.
    Type: Application
    Filed: December 3, 2009
    Publication date: January 19, 2012
    Applicant: Tel HaShomer Medical Research Infrastructure and Services Ltd.
    Inventors: Tamar Rubinek, Ido Wolf, Eitan Friedman, Bella Kaufman
  • GLP-1 Receptor Agonists And Related Active Pharmaceutical Ingredients For Treatment Of Cancer
    Publication number: 20110046071
    Abstract: Disclosed are methods and compositions for increasing concentrations of GLP-1 receptor agonists in the body for the treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic agents or hormone-regulating agents.
    Type: Application
    Filed: March 4, 2009
    Publication date: February 24, 2011
    Applicant: TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
    Inventors: Avraham Karasik, Tamar Rubinek, Ido Wolf, Bella Kaufman
  • KLOTHO PROTEIN AND RELATED COMPOUNDS FOR THE TREATMENT AND DIAGNOSIS OF CANCER
    Publication number: 20100330062
    Abstract: Disclosed is the use of a klotho protein or related compounds for the diagnosis and treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic agents or hormone-regulating agents.
    Type: Application
    Filed: May 6, 2008
    Publication date: December 30, 2010
    Inventors: H. Phillip Koeffler, Ido Wolf, Tamar Rubinek, Bella Kaufman, Lilach Abramovitch