Patents by Inventor Tamara Balac Sipes

Tamara Balac Sipes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF SELECTING AN ACTIVE OLIGONUCLEOTIDE PREDICTIVE MODEL
    Publication number: 20090082975
    Abstract: The present invention provides a method of identifying a predictor of antisense oligonucleotide activity by identifying properties of oligonucleotides, evaluating oligonucleotide activity of the oligonucleotides, and correlating oligonucleotide activity with the properties. A high correlation between oligonucleotide activity and a property indicates that the property is a predictor of oligonucleotide activity.
    Type: Application
    Filed: September 24, 2008
    Publication date: March 26, 2009
    Applicant: Isis Pharmaceuticals, Inc.
    Inventors: Tamara Balac Sipes, Susan M. Freier, Kenneth Dobie
  • Method of selecting an active oligonucleotide predictive model
    Publication number: 20050026198
    Abstract: The present invention provides a method of identifying a predictor of antisense oligonucleotide activity by identifying properties of oligonucleotides, evaluating oligonucleotide activity of the oligonucleotides, and correlating oligonucleotide activity with the properties. A high correlation between oligonucleotide activity and a property indicates that the property is a predictor of oligonucleotide activity.
    Type: Application
    Filed: June 28, 2004
    Publication date: February 3, 2005
    Inventors: Tamara Balac Sipes, Susan Freier, Kenneth Dobie
  • Modulation of mitochondrial ribosome protein S16 expression
    Publication number: 20040115633
    Abstract: Compounds, compositions and methods are provided for modulating the expression of mitochondrial ribosome protein S16. The compositions comprise oligonucleotides, targeted to nucleic acid encoding mitochondrial ribosome protein S16. Methods of using these compounds for modulation of mitochondrial ribosome protein S16 expression and for diagnosis and treatment of disease associated with expression of mitochondrial ribosome protein S16 are provided.
    Type: Application
    Filed: December 10, 2002
    Publication date: June 17, 2004
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Kenneth W. Dobie, Tamara Balac Sipes
  • Modulation of SLC26A2 expression
    Publication number: 20040110155
    Abstract: Compounds, compositions and methods are provided for modulating the expression of SLC26A2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding SLC26A2. Methods of using these compounds for modulation of SLC26A2 expression and for diagnosis and treatment of disease associated with expression of SLC26A2 are provided.
    Type: Application
    Filed: December 10, 2002
    Publication date: June 10, 2004
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Kenneth W. Dobie, Tamara Balac Sipes
  • Modulation of SEDL expression
    Publication number: 20040110160
    Abstract: Compounds, compositions and methods are provided for modulating the expression of SEDL. The compositions comprise oligonucleotides, targeted to nucleic acid encoding SEDL. Methods of using these compounds for modulation of SEDL expression and for diagnosis and treatment of disease associated with expression of SEDL are provided.
    Type: Application
    Filed: December 10, 2002
    Publication date: June 10, 2004
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Kenneth W. Dobie, Tamara Balac Sipes
  • Modulation of mitochondrial ribosomal protein L13 expression
    Publication number: 20040110158
    Abstract: Compounds, compositions and methods are provided for modulating the expression of mitochondrial ribosomal protein L13. The compositions comprise oligonucleotides, targeted to nucleic acid encoding mitochondrial ribosomal protein L13. Methods of using these compounds for modulation of mitochondrial ribosomal protein L13 expression and for diagnosis and treatment of disease associated with expression of mitochondrial ribosomal protein L13 are provided.
    Type: Application
    Filed: December 10, 2002
    Publication date: June 10, 2004
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Kenneth W. Dobie, Tamara Balac Sipes
  • Modulation of zinedin expression
    Publication number: 20040110701
    Abstract: Compounds, compositions and methods are provided for modulating the expression of zinedin. The compositions comprise oligonucleotides, targeted to nucleic acid encoding zinedin. Methods of using these compounds for modulation of zinedin expression and for diagnosis and treatment of disease associated with expression of zinedin are provided.
    Type: Application
    Filed: December 10, 2002
    Publication date: June 10, 2004
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Kenneth W. Dobie, Tamara Balac Sipes