Patents by Inventor Tamara Colette Baynham
Tamara Colette Baynham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7774057Abstract: A gene regulatory system detects ischemia events and is capable of delivering a biologic therapy in response to the detection of an ischemic event or the reception of a command. The biologic therapy protects the heart from ischemic damage by regulating the expression of an exogenously introduced gene product. In one embodiment, the gene regulatory system includes an implantable system that emits at least one gene regulatory signal in response to the detection of the ischemic event or the reception of the command. The gene regulatory signal directly or indirectly regulates gene expression of the gene product.Type: GrantFiled: September 6, 2005Date of Patent: August 10, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph M. Pastore, Jeffrey Ross, Tamara Colette Baynham, Rodney W. Salo, Andrew P. Kramer, Julio C. Spinelli
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Patent number: 7764999Abstract: A method and apparatus are disclosed for treating mitral regurgitation with electrical stimulation. By providing pacing stimulation to a region of the left ventricle in proximity to the mitral valve apparatus in a manner which pre-excites the region during early ventricular systole, a beneficial effect is obtained which can prevent or reduce the extent of mitral regurgitation.Type: GrantFiled: January 28, 2005Date of Patent: July 27, 2010Assignee: Cardiac Pacemakers, Inc.Inventor: Tamara Colette Baynham
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Publication number: 20100145401Abstract: Various system embodiments comprise a neural stimulator, a pulse generator, and a controller. The neural stimulator is adapted to generate a neural stimulation signal. The pulse generator is adapted to generate a pacing signal to provide myocardium pacing. The controller is adapted to control the neural stimulator and the pulse generator to provide a cardioprotective conditioning therapy. The conditioning therapy includes neural stimulation to elicit a parasympathetic response and myocardium pacing. Other aspects and embodiments are provided herein.Type: ApplicationFiled: February 10, 2010Publication date: June 10, 2010Inventors: Joseph M. Pastore, Tamara Colette Baynham, Andrew P. Kramer, Julio C. Spinelli, Jeffrey Ross, Rodney W. Salo
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Publication number: 20100130913Abstract: Disclosed herein, among other things, is a system for providing pacing during revascularization. An embodiment of the system includes an angioplasty or stent delivery catheter system having a catheter, a balloon and an inflation device adapted to inflate and deflate the balloon for delivery of a stent. The embodiment also includes a programmable pulse generator and at least one electrode integrated with the angioplasty catheter system, where the pulse generator is connected to the electrode. In various embodiments, at least one integrated sensor is connected to the angioplasty catheter system. The sensor is adapted to sense a parameter indicative of flow restoration and trigger the pulse generator to begin pacing based on the parameter.Type: ApplicationFiled: January 27, 2010Publication date: May 27, 2010Inventors: Tamara Colette Baynham, Steven D. Girouard
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Patent number: 7711420Abstract: Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing but may also be hazardous. Described herein is a method and system that uses measures of ventricular dyssynchrony or a patient's physiological response to ventricular dyssynchrony to control the delivery of cardioprotective pre-excitation pacing in closed-loop fashion.Type: GrantFiled: March 19, 2007Date of Patent: May 4, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Tamara Colette Baynham, Quan Ni, Shelley M. Cazares, Kevin J. Stalsberg, Yi Zhang
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Patent number: 7689286Abstract: Various system embodiments comprise a neural stimulator, a pulse generator, and a controller. The neural stimulator is adapted to generate a neural stimulation signal. The pulse generator is adapted to generate a pacing signal to provide myocardium pacing. The controller is adapted to control the neural stimulator and the pulse generator to provide a cardioprotective conditioning therapy. The conditioning therapy includes neural stimulation to elicit a parasympathetic response and myocardium pacing. Other aspects and embodiments are provided herein.Type: GrantFiled: May 2, 2006Date of Patent: March 30, 2010Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph M. Pastore, Tamara Colette Baynham, Andrew P. Kramer, Julio C. Spinelli, Jeffrey Ross, Rodney W. Salo
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Publication number: 20090318990Abstract: Cardioprotective pacing is applied to prevent and/or reduce cardiac injury associated with myocardial infarction (MI) and revascularization procedure. Pacing pulses are generated from a pacemaker and delivered through one or more pacing electrodes incorporated onto one or more percutaneous transluminal vascular intervention (PTVI) devices during the revascularization procedure. In one embodiment, a PTVI device includes an expandable distal end to provide a stable electrical contact between a pacing electrode and the vascular wall of a blood vessel when the distal end is placed in the blood vessel.Type: ApplicationFiled: June 15, 2009Publication date: December 24, 2009Inventors: Daniel K. Tomaschko, Matthew C. Heidner, David James Broman, Tracee Eidenschink, Tamara Colette Baynham
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Publication number: 20090318993Abstract: Cardioprotective pacing is applied to prevent and/or reduce cardiac injury associated with myocardial infarction (MI) and revascularization procedure. Pacing pulses are generated from a flexible pacemaker circuit integrated with a percutaneous transluminal vascular intervention (PTVI) device and delivered through pacing electrodes incorporated onto the PTVI device during the revascularization procedure.Type: ApplicationFiled: June 15, 2009Publication date: December 24, 2009Inventors: Tracee Eidenschink, Roger Hastings, Tamara Colette Baynham
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Publication number: 20090318943Abstract: Cardioprotective pacing is applied to prevent and/or reduce cardiac injury associated with myocardial infarction (MI) and revascularization procedure. Pacing pulses are generated from a pacemaker and delivered through pacing electrodes incorporated onto percutaneous transluminal vascular intervention (PTVI) devices during the revascularization procedure. Examples of the PTVI devices include a guide catheter, a guide wire, and an angioplasty catheter such as a balloon catheter used in the revascularization procedure. The pacing electrodes are incorporated onto such PTVI devices in various ways.Type: ApplicationFiled: June 15, 2009Publication date: December 24, 2009Inventors: Tracee Eidenschink, David James Broman, Matthew C. Heidner, Mark Schwartz, Daniel K. Tomaschko, Tamara Colette Baynham, Richard J. Olson
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Patent number: 7630760Abstract: A neural stimulation therapy system for atherosclerotic plaques is provided. One aspect of this disclosure relates to a medical device for applying neural stimulation therapy for atherosclerotic plaques. The device includes a neural stimulator adapted to deliver an electrical signal through at least one electrode to an autonomic neural target. The device also includes a controller to control the neural stimulator to provide a therapy for atherosclerotic plaques. The device is external to a human body in an embodiment, and includes an implantable medical device (IMD) in various embodiments. According to an embodiment, the device includes a neural stimulation lead connected to the neural stimulator. The neural stimulator delivers electrical signals with waveform parameters based on sensed arterial blockage levels, according to various embodiments. Other aspects and embodiments are provided herein.Type: GrantFiled: November 21, 2005Date of Patent: December 8, 2009Assignee: Cardiac Pacemakers, Inc.Inventors: Imad Libbus, Julio C. Spinelli, Tamara Colette Baynham
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Publication number: 20090143835Abstract: An implantable cardiac protection pacing system delivers pacing pulses to protect the heart from injuries associated with ischemia and myocardial infarction. The system includes an implantable pulse generator (PG) that delivers the pacing pulses and a coronary stent electrically connected to the implantable PG to function as a pacing electrode through which the pacing pulses are delivered. In one embodiment, an intravascular lead provides the electrical connection between the coronary stent and the implantable PG to allow the implantable PG to be implanted in the femoral region. In another embodiment, the coronary stent and the implantable PG are integrated into an intravascular pulse generator-stent.Type: ApplicationFiled: February 2, 2009Publication date: June 4, 2009Inventors: Joseph M. Pastore, Andrew P. Kramer, Julio C. Spinelli, Rodney W. Salo, Tamara Colette Baynham, Jeffrey Ross, Frits W. Prinzen, Ward Y. R. Vanagt, Richard N. Cornelussen
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Publication number: 20080281305Abstract: An implantable medical device includes a light emitting circuit incorporated into an intravascular stent. The light emitting circuit emits a light to an ischemic region. The light has characteristics suitable for reliving the angina symptoms associated with ischemia.Type: ApplicationFiled: May 10, 2007Publication date: November 13, 2008Applicant: Cardiac Pacemakers, Inc.Inventors: Tamara Colette Baynham, Darrell O. Wagner, Haris J. Sih
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Publication number: 20080234774Abstract: Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing but may also be hazardous. Described herein is a method and system that uses measures of ventricular dyssynchrony or a patient's physiological response to ventricular dyssynchrony to control the delivery of cardioprotective pre-excitation pacing in closed-loop fashion.Type: ApplicationFiled: March 19, 2007Publication date: September 25, 2008Applicant: CARDIAC PACEMAKERS, INC.Inventors: Tamara Colette Baynham, Quan Ni, Shelley Cazares, Kevin J. Stalsberg
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Publication number: 20080221636Abstract: A cardiac pacing system controls the progression of a cardiac disorder such as heart failure by delivering cardiac pacing to create or augment regional stress in the heart. The cardiac pacing is delivered intermittently, such as on a periodic basis, according to a cardiac stress augmentation pacing sequence that includes alternating pacing and non-pacing periods. One or more physiological signals are monitored for closed-loop control of the cardiac pacing using baseline characteristics of the cardiac disorder, acute cardiac stress created by the cardiac pacing, and/or risk associated with the cardiac pacing.Type: ApplicationFiled: March 6, 2007Publication date: September 11, 2008Applicant: CARDIAC PACEMAKERS, INC.Inventors: Joseph M. Pastore, Tamara Colette Baynham, Donald L. Hopper, Allan C. Shuros, Shantha Arcot-Krishnamurthy
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Publication number: 20080177194Abstract: A system including an implantable trigger event detector and an implantable ischemia detector. The implantable trigger event detector is adapted to detect at least one first condition and to output a responsive trigger signal including information about whether the first condition has been detected. The implantable ischemia detector is adapted to detect a second condition indicative of one or more physiologic cardiovascular events in a subject that are indicative of ischemia. The ischemia detector is coupled to the trigger event detector to receive the trigger signal, and the ischemia detector is enabled upon the trigger signal indicating that the first condition has been detected.Type: ApplicationFiled: January 19, 2007Publication date: July 24, 2008Applicant: CARDIAC PACEMAKERS, INC.Inventors: Yi Zhang, Richard Fogoros, Julie Thompson, Bruce H. KenKnight, Michael J. Pederson, Abhilash Patangay, Tamara Colette Baynham, Yatheendhar D. Manicka, Scott T. Mazar
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Publication number: 20080119904Abstract: A method and device for treating myocardial ischemia are described in which the stress experienced by a myocardial region identified as vulnerable to becoming ischemic is varied with pre-excitation pacing. In an unloading mode, pacing is applied in proximity to the vulnerable region to reduce stress and the metabolic demand of the region. In a loading mode, pacing is applied to a region remote from the vulnerable region in order to produce a conditioning effect.Type: ApplicationFiled: November 17, 2006Publication date: May 22, 2008Applicant: Cardiac Pacemakers, Inc.Inventors: Rodney W. Salo, Allan C. Shuros, Tamara Colette Baynham
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Publication number: 20080097412Abstract: Described herein are a method and apparatus for introducing instrumentation into the lymphatic system that can be used for physiological monitoring and/or delivery of therapy. Such instrumentation, for example, may include one or more sensors for measuring physiological variables and/or one or more instruments for delivering therapy that is adapted to be disposed within a lymphatic vessel.Type: ApplicationFiled: September 1, 2006Publication date: April 24, 2008Inventors: Allan C. Shuros, Andrew P. Kramer, Tamara Colette Baynham, James Cawthra, M. Jason Brooke
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Publication number: 20080071315Abstract: Disclosed herein, among other things, is a system for providing pacing during revascularization. An embodiment of the system includes an angioplasty or stent delivery catheter system having a catheter, a balloon and an inflation device adapted to inflate and deflate the balloon for delivery of a stent. The embodiment also includes a programmable pulse generator and at least one electrode integrated with the angioplasty catheter system, where the pulse generator is connected to the electrode. In various embodiments, at least one integrated sensor is connected to the angioplasty catheter system. The sensor is adapted to sense a parameter indicative of flow restoration and trigger the pulse generator to begin pacing based on the parameter.Type: ApplicationFiled: August 31, 2006Publication date: March 20, 2008Inventors: Tamara Colette Baynham, Steven D. Girouard
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Publication number: 20080058881Abstract: An implantable device for delivering phototherapy is described that enables the phototherapy to be delivered to internal locations in either a clinical or ambulatory setting for treatment of post-MI patients. Telemetry circuitry enables the device to deliver the phototherapy upon command or be programmed to delivery the phototherapy according to a specified schedule. The device may also incorporate one or more sensing modalities that can be used to trigger delivery of phototherapy upon occurrence of a sensed event or condition. In one particular embodiment, the phototherapy device is incorporated into a cardiac rhythm management device that also delivers pacing and/or defibrillation therapy.Type: ApplicationFiled: September 1, 2006Publication date: March 6, 2008Applicant: CARDIAC PACEMAKERS, INCInventors: Darrell O. Wagner, Haris J. Sih, Tamara Colette Baynham, Steven D. Girouard, Joseph M. Pastore, Mark Schwartz
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Patent number: 7289849Abstract: A method and apparatus are disclosed for treating mitral regurgitation with electrical stimulation. By providing pacing stimulation to the left atrium during ventricular systole, a beneficial effect is obtained which can prevent or reduce the extent of mitral regurgitation.Type: GrantFiled: January 28, 2005Date of Patent: October 30, 2007Assignee: Cardiac Pacemakers, Inc.Inventor: Tamara Colette Baynham