Patents by Inventor Tamara Minko

Tamara Minko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Strategies to enhance lung cancer treatment
    Patent number: 11896713
    Abstract: A nanocarrier containing a combination of bioactive agents is provided. The nanocarrier allows for targeted delivery of the agents to cancer cells with minimized side effect.
    Type: Grant
    Filed: October 22, 2021
    Date of Patent: February 13, 2024
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Tamara Minko, Olga B. Garbuzenko
  • Strategies to Enhance Lung Cancer Treatment
    Publication number: 20220125728
    Abstract: A nanocarrier containing a combination of bioactive agents is provided. The nanocarrier allows for targeted delivery of the agents to cancer cells with minimized side effect.
    Type: Application
    Filed: October 22, 2021
    Publication date: April 28, 2022
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Tamara Minko, Olga B. Garbuzenko
  • Nanotechnology approach for inhalation therapies
    Patent number: 9445993
    Abstract: This invention relates to lipid nanoparticle compositions and methods for the localized delivery of active agents via inhalation therapy.
    Type: Grant
    Filed: April 16, 2013
    Date of Patent: September 20, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Tamara Minko, Olga B. Garbuzenko, Vera Ivanova
  • E2F as a target of hormone refractory prostate cancer
    Patent number: 9314497
    Abstract: The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.
    Type: Grant
    Filed: September 2, 2014
    Date of Patent: April 19, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Joseph R. Bertino, Debabrata Banerjee, Tamara Minko, Olga B. Garbuzenko, Xiaoqi Xie, John E. Kerrigan, Emine E. Abali, Kathleen W. Scotto
  • Compositions and methods for delivering nucleic acid molecules and treating cancer
    Patent number: 9289505
    Abstract: The present invention provides compositions and methods for the delivery of nucleic acids to a cell. The present invention additionally provides compositions and methods for the treatment of a disease or disorder, particularly cancer. In a particular embodiment, the composition comprises at least one pharmaceutically acceptable carrier and at least one liposome or dendrimer comprising at least two chemotherapeutic agents with different mechanisms of action and at least two inhibitors of cellular drug resistance.
    Type: Grant
    Filed: August 17, 2011
    Date of Patent: March 22, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Tamara Minko, Lorna Rodriguez-Rodriguez, Olga B. Garbuzenko, Oleh Taratula, Vatsal Shah
  • E2F AS A TARGET OF HORMONE REFRACTORY PROSTATE CANCER
    Publication number: 20150202248
    Abstract: The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.
    Type: Application
    Filed: September 2, 2014
    Publication date: July 23, 2015
    Inventors: Joseph R. Bertino, Debabrata Banerjee, Tamara Minko, Olga B. Garbuzenko, Xiaoqi Xie, John E. Kerrigan, Emine E. Abali, Kathleen W. Scotto
  • E2F as a target of hormone refractory prostate cancer
    Patent number: 8822421
    Abstract: The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.
    Type: Grant
    Filed: October 14, 2011
    Date of Patent: September 2, 2014
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Joseph R. Bertino, Debabrata Banerjee, Tamara Minko, Olga B. Garbuzenko, Xiaoqi Xie, John E. Kerrigan, Emine E. Abali, Kathleen W. Scotto
  • Compositions and Methods for Delivering Nucleic Acid Molecules and Treating Cancer
    Publication number: 20130302257
    Abstract: The present invention provides compositions and methods for the delivery of nucleic acids to a cell. The present invention additionally provides compositions and methods for the treatment of a disease or disorder, particularly cancer.
    Type: Application
    Filed: August 17, 2011
    Publication date: November 14, 2013
    Applicants: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Tamara Minko, Lorna Rodriguez-Rodriguez, Olga B. Garbuzenko, Oleh Taratula, Vatsal Shah
  • NANOTECHNOLOGY APPROACH FOR INHALATION THERAPIES
    Publication number: 20130273164
    Abstract: This invention relates to lipid nanoparticle compositions and methods for the localized delivery of active agents via inhalation therapy.
    Type: Application
    Filed: April 16, 2013
    Publication date: October 17, 2013
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Tamara Minko, Olga B. Garbuzenko, Vera Ivanova
  • ENHANCED ORAL TRANSCOMPARTMENTAL DELIVERY OF THERAPEUTIC OR DIAGANOSTIC AGENTS
    Publication number: 20130072447
    Abstract: The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.
    Type: Application
    Filed: May 14, 2012
    Publication date: March 21, 2013
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Srinivasan Ramanathan, Stanley Stein, Michael Leibowitz, Patrick J. Sinko, Tamara Minko, Gregory C. Williams, Goubao Zhang, Xiaoping Zhang, Shahrair Pooyan, Seong Hee Park, Bo Qiu, Pankaj Paranjpe
  • E2F AS A TARGET OF HORMONE REFRACTORY PROSTATE CANCER
    Publication number: 20120093919
    Abstract: The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.
    Type: Application
    Filed: October 14, 2011
    Publication date: April 19, 2012
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
    Inventors: Joseph R. Bertino, Debabrata Banerjee, Tamara Minko, Olga B. Garbuzenko, Xiaoqi Xie, John E. Kerrigan, Emine E. Abali, Kathleen W. Scotto
  • Complex drug delivery composition and method for treating cancer
    Patent number: 8124051
    Abstract: The present invention relates to compositions and methods for producing a complex drug delivery system which specifically targets cancer cells, has an increase in cellular uptake, is cytotoxic, and suppresses antiapoptotic cellular defenses.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: February 28, 2012
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Tamara Minko, Patrick J. Sinko, Stanley Stein
  • ENHANCED ORAL TRANSCOMPARTMENTAL DELIVERY OF THERAPEUTIC OR DIAGNOSTIC AGENTS
    Publication number: 20110087004
    Abstract: The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.
    Type: Application
    Filed: June 18, 2010
    Publication date: April 14, 2011
    Inventors: Srinivasan Ramanathan, Stanley Stein, Michael Leibowitz, Patrick J. Sinko, Tamara Minko, Gregory C. Williams, Goubao Zhang, Xiaoping Zhang, Shahrair Pooyan, Seong Hee Park, Bo Qiu, Pankaj Paranjpe
  • Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents
    Patent number: 7740882
    Abstract: The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.
    Type: Grant
    Filed: June 29, 2005
    Date of Patent: June 22, 2010
    Inventors: Srinivasan Ramanathan, Stanley Stein, Michael Leibowitz, Patrick J. Sinko, Tamara Minko, Gregory C. Williams, Goubao Zhang, Xiaoping Zhang, Shahrair Pooyan, Seong Hee Park, Bo Qiu, Pankaj Paranjpe
  • COMPLEX DRUG DELIVERY COMPOSITION AND METHOD FOR TREATING CANCER
    Publication number: 20080280813
    Abstract: The present invention relates to compositions and methods for producing a complex drug delivery system which specifically targets cancer cells, has an increase in cellular uptake, is cytotoxic, and suppresses antiapoptotic cellular defenses.
    Type: Application
    Filed: June 27, 2008
    Publication date: November 13, 2008
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Tamara MINKO, Patrick J. Sinko, Stanley Stein
  • Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents
    Publication number: 20060029667
    Abstract: The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.
    Type: Application
    Filed: June 29, 2005
    Publication date: February 9, 2006
    Inventors: Srinivasan Ramanathan, Stanley Stein, Michael Leibowitz, Patrick Sinko, Tamara Minko, Gregory Williams, Goubao Zhang, Xiaoping Zhang, Shahrair Pooyan, Seong Park, Bo Qiu, Pankaj Paranjpe
  • Complex drug delivery composition and method for treating cancer
    Publication number: 20050043215
    Abstract: The present invention relates to compositions and methods for producing a complex drug delivery system which specifically targets cancer cells, has an increase in cellular uptake, is cytotoxic, and suppresses antiapoptotic cellular defenses.
    Type: Application
    Filed: February 17, 2004
    Publication date: February 24, 2005
    Inventors: Tamara Minko, Patrick Sinko, Stanley Stein
  • Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents
    Publication number: 20030091640
    Abstract: The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.
    Type: Application
    Filed: February 8, 2002
    Publication date: May 15, 2003
    Inventors: Srinivasan Ramanathan, Stanley Stein, Michael Leibowitz, Patrick J. Sinko, Tamara Minko, Gregory C. Williams, Goubao Zhang, Xiaoping Zhang, Shahrair Pooyan, Seong Hee Park, Bo Qiu, Pankaj Paranjpe