Patents by Inventor Tamara Tugal

Tamara Tugal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A COMPOSITION COMPRISING A NOTCH LIGAND AND AN ALLERGENB OR ALLERGEN BYSTANDER ANTIGEN
    Publication number: 20100303867
    Abstract: A method is provided for reducing an immune response to an allergen or antigenic determinant thereof in a mammal by administering a modulator of the Notch signalling pathway.
    Type: Application
    Filed: April 23, 2010
    Publication date: December 2, 2010
    Inventors: MARK WILLIAM BODMER, EMMANUEL CYRILLE PASCAL BRIEND, BRIAN ROBERT CHAMPION, ANDREW CHRISTOPHER LENNARD, GRAHAME JAMES MCKENZIE, SILVIA RAGNO, TAMARA TUGAL, GEORGE ALBERT WARD, LESLEY LYNN YOUNG
  • Treatment of allergic diseases using a modulator of the Notch signaling pathway
    Publication number: 20060205823
    Abstract: A method is provided for reducing an immune response to an allergen or antigenic determinant thereof in a mammal by administering a modulator of the Notch signalling pathway.
    Type: Application
    Filed: September 21, 2005
    Publication date: September 14, 2006
    Inventors: Mark Bodmer, Emmanuel Briend, Brian Champion, Andrew Lennard, Grahame McKenzie, Silvia Ragno, Tamara Tugal, George Ward, Lesley Young
  • Conjugate of notch signalling pathway modulators and their use in medical treatment
    Publication number: 20060002924
    Abstract: Conjugates comprising a plurality of modulators of the Notch signalling pathway chemically bound to a support structure are described. The conjugates are useful for modulation of the Notch signalling pathway and treatment of associated conditions.
    Type: Application
    Filed: February 3, 2005
    Publication date: January 5, 2006
    Inventors: Mark Bodmer, Brian Champion, Andrew Lennard, Grahame McKenzie, Tamara Tugal, George Ward
  • Pharmaceutical compositions and medical treatments comprising notch ligand proteins
    Publication number: 20050261477
    Abstract: Provided is a Notch ligand protein or polypeptide comprising a Notch ligand DSL domain; 1 to 5 (but no more than 5) Notch ligand EGF repeat domains; optionally, all or part of a Notch ligand N-terminal domain; and optionally, one or more heterologous amino acid sequences. Also provided is a homogeneous or heterogeneous multimer of the protein or polypeptide and a polynucleotide encoding the Notch ligand protein or polypeptide. An immune response can be modified in a subject by administering the Notch ligand protein or polypeptide to the subject.
    Type: Application
    Filed: March 10, 2005
    Publication date: November 24, 2005
    Inventors: Brian Champion, Andrew Lennard, Grahame McKenzie, Tamara Tugal
  • Modulators of the Notch signalling pathway and uses thereof in medical treatment
    Publication number: 20050220886
    Abstract: A method is disclosed for therapeutic modulation of Notch signalling by administering a construct comprising a multiplicity of bond, linked or immobilised modulators of Notch signalling.
    Type: Application
    Filed: October 5, 2004
    Publication date: October 6, 2005
    Inventors: Mark Bodmer, Emmanuel Briend, Brian Champion, Andrew Lennard, Grahame Mckenzie, Tamara Tugal, George Ward, Lesley Young
  • Medical treatment
    Publication number: 20050137130
    Abstract: An inhibitor of the Notch signalling pathway is provided for use as an immunostimulant, for example as a vaccine adjuvant.
    Type: Application
    Filed: May 14, 2004
    Publication date: June 23, 2005
    Inventors: Mark Bodmer, Emmanuel Pascal Briend, Brian Champion, Andrew Lennard, Grahame Mckenzie, Silvia Ragno, Tamara Tugal, Lesley Young
  • Method for detecting modulators of Notch signalling
    Publication number: 20050059093
    Abstract: A method for detecting modulators of Notch signalling is described. The method includes the step of monitoring Notch signalling in a cell of the immune system in the presence of a candidate modulator.
    Type: Application
    Filed: January 23, 2004
    Publication date: March 17, 2005
    Inventors: Mark Bodmer, Emmanuel Cyrille Briend, Brian Champion, Grahame McKenzie, Tamara Tugal, George Ward, Lesley Young
  • Medical treatment
    Publication number: 20050026831
    Abstract: An inhibitor of the Notch signalling pathway is provided for the manufacture of a medicament for use in the treatment of cancer.
    Type: Application
    Filed: May 14, 2004
    Publication date: February 3, 2005
    Inventors: Mark Bodmer, Emmanuel Briend, Brian Champion, Andrew Lennard, Grahame McKenzie, Silvia Ragno, Tamara Tugal, Lesley Young