Patents by Inventor Tamas Szen

Tamas Szen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Steroselective hydrogenation process
    Patent number: 5097031
    Abstract: The invention relates to a novel stereoselective process for the preparation of dihdyrolysergol from lysergol by hydrogenation in the presence of solvent and palladium catalyst applied on a carrier, which comprises hydrogenating lysergol in the presence of one or more aprotic solvent(s) containing tertiary nitrogen atom(s) and a palladium catalyst applied on activated carbon, and recovering the product obtained from the reaction mixture in a known manner.
    Type: Grant
    Filed: June 22, 1990
    Date of Patent: March 17, 1992
    Assignee: Richter Gedeon Vegyeszeti Gyar R.T.
    Inventors: Istvan Polgar, Jozsef Foldesi, Janos Kiss, Piroska Major nee Forstner, Karoly Molnar, Andras Sugar, Tamas Szen, Katalin Balogh nee Nemes
  • Process for preparing 17.alpha.-hydroxy-pregn-4-en-3,20-dione
    Patent number: 4482494
    Abstract: The invention relates to a novel process for the preparations of pregnane derivatives of formula I, ##STR1## wherein R.sup.1 stands for a methyl or an ethyl group,R.sup.2 represents a hydrogen atom or a methyl group, andX is a hydrogen atom or a formyl or acetyl group, and the bond indicated by a dotted and a continuous line stands for a single or a double bond beween the two neighboring carbon atoms.According to the invention a trifluoroacetate ester of formula II, ##STR2## wherein R.sup.1 and R.sup.2 are as defined above, is reacted with formic acid or acetic acid in the presence of a catalytic amount of a mercury salt in a dipolar proton-free or basic solvent. The formyl or acetyl group being in the place of X can be split off in a way known per se.The process provides a novel advantageous method for building up the pregnane side chain characteristic of corticoids.
    Type: Grant
    Filed: October 20, 1982
    Date of Patent: November 13, 1984
    Assignee: Richter Gedeon Vegyeszeti Gyar R.T.
    Inventors: Anna Boor, Jozsef Toth, Tamas Szen, Laszlo Gabor, Piroska Major nee Feistner, Sandor Holly
  • Process for preparing 17.alpha.-hydroxy-pregn-4-en-3,20-dione derivatives
    Patent number: 4368160
    Abstract: The invention relates to a novel process for the preparation of pregnane derivatives of formula I, ##STR1## wherein R.sup.1 stands for a methyl or an ethyl group,R.sup.2 represents a hydrogen atom or a methyl group, andX is a hydrogen atom or a formyl or acetyl group, and the bond indicated by a dotted and a continuous line stands for a single or a double bond between the two neighboring carbon atoms.According to the invention a trifluoroacetate ester of formula II, ##STR2## wherein R.sup.1 and R.sup.2 are as defined above, is reacted with formic acid or acetic acid in the presence of a catalytic amount of a mercury salt in a dipolar proton-free or basic solvent. The formyl or acetyl group being in the place of X can be split off in a way known per se.The process provides a novel advantageous method for building up the pregnane side chain characteristic of corticoids.
    Type: Grant
    Filed: April 2, 1982
    Date of Patent: January 11, 1983
    Assignee: Richter Gedeon Vegyeszeti Gyar R.T.
    Inventors: Anna Boor nee Mezei, Jozsef Toth, Tamas Szen, Laszlo Gabor, Piroska Major nee Fastner, Sandor Holly