Abstract: The invention aims at providing an adsorbent for bacterial toxins, a method for removal of such toxins by adsorption, and an adsorber packed with said adsorbent. Provided are an adsorbent for bacterial toxins, which comprises a water-insoluble porous material having a mode of pore radius of 20 angstroms to 1,000 angstroms, a method for removal of bacterial toxins using said adsorbent, and an adsorber packed with said adsorbent.

Abstract: The invention aims at providing an adsorbent for bacterial toxins, a method for removal of such toxins by adsorption, and an adsorber packed with said adsorbent. Provided are an adsorbent for bacterial toxins, which comprises a water-insoluble porous material having a mode of pore radius of 20 angstroms to 1,000 angstroms, a method for removal of bacterial toxins using said adsorbent, and an adsorber packed with said adsorbent.

Abstract: The present invention is directed to an enterotoxin adsorbent comprising a compound having a log P (P denotes a partition coefficient in an octanol-water system) value of not less than 2.50 as immobilized on a water-insoluble carrier.

Abstract: The present invention provides an adsorbent for efficiently adsorbing and removing cytokine in liquid and a method for removing cytokine in liquid by the adsorbent. Also, the present invention provides an adsorber for removing cytokine in liquid. Specifically, an adsorbent for cytokine is obtained by immobilizing a compound having a log P value of at least 2.50 (P is the partition coefficient in an octanol-water system) on a water-insoluble carrier. By contacting a liquid containing cytokine with the adsorbent for cytokine, the cytokine in the liquid can be effectively adsorbed and removed. Furthermore, cytokine can be efficiently adsorbed and removed by an adsorber comprising a container having an inlet and an outlet for liquid and a means for preventing the adsorbent from flowing out of the container, which is filled with the adsorbent.

Abstract: An adsorbent suitable for adsorption of a transforming growth factor-? (TGF-?) comprising a compound which has a log P value of at least 2.50 wherein P is a partition coefficient in an octanol-water system and which is immobilized on a water-insoluble carrier. TGF-? present in a body fluid can be efficiently removed by bringing the body fluid into contact with the adsorbent.

Abstract: There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The adsorbent of endogenous cannabinoid comprising an adsorbent for endogenous cannabinoid comprising a water-insoluble material containing a substance whose solubility parameter &dgr; is at most 12 ((cal/cm3)1/2) is obtained. Endogenous cannabinoid in fluid can be effectively adsorbed and removed by contacting the adsorbent of endogenous cannabinoid with fluid containing endogenous cannabinoid.

Abstract: There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The adsorbent of endogenous cannabinoid is obtained by fixing a compound having a log P value (P indicating distribution coefficient in octanol-water system) of at least 3.50 on a water-insoluble carrier. Endogenous cannabinoid in fluid can be adsorbed and removed in an effective manner by contacting the adsorbent of endogenous cannabinoid with fluid containing endogenous cannabinoid.

Abstract: There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The adsorbent of endogenous cannabinoid comprising an adsorbent for endogenous cannabinoid comprising a water-insoluble material containing a substance whose solubility parameter &dgr; is at most 12 ((cal/ cm3)½) is obtained. Endogenous cannabinoid in fluid can be effectively adsorbed and removed by contacting the adsorbent of endogenous cannabinoid with fluid containing endogenous cannabinoid.

Abstract: The present invention is directed to an enterotoxin adsorbent comprising a compound having a log P (P denotes a partition coefficient in an octanol-water system) value of not less than 2.50 as immobilized on a water-insoluble carrier.

Abstract: There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The adsorbent of endogenous cannabinoid is obtained by fixing a compound having a log P value (P indicating distribution coefficient in octanol-water system) of at least 3.50 on a water-insoluble carrier. Endogenous cannabinoid in fluid can be adsorbed and removed in an effective manner by contacting the adsorbent of endogenous cannabinoid with fluid containing endogenous cannabinoid.

Abstract: An adsorbent suitable for adsorption of a transforming growth factor-&bgr; (TGF-&bgr;) comprising a compound which has a log P value of at least 2.50 wherein P is a partition coefficient in an octanol-water system and which is immobilized on a water-insoluble carrier. TGF-&bgr; present in a body fluid can be efficiently removed by bringing the body fluid into contact with the adsorbent.

Abstract: The present invention relates to a method for producing a microgranulated particle having particle size of not more than 0.2 mm, wherein a fine powder with the average particle size of not more than 10 .mu.m, which is being agitated, tumbled or fluidized, is granulated, with a solution containing a binder alone or a binder and a surfactant being sprayed onto the surface thereof. The present invention allows to produce pharmaceutical preparations for poorly soluble and poorly absorbable drugs and preparations requiring a high content of the active ingredient. Also, it can provide an easy-to-handle powdery microgranulated particle in the field of food and fertilizers.