Abstract: A method produces a biphenyl derivative, with an industrially high yield and excellent productivity, by use of a raw material which is low in cost and toxicity. The method for producing the biphenyl derivative represented by Formula (1) is characterized in that a chlorine atom in a benzene derivative represented by Formula (2) reacts with magnesium metal to convert the benzene derivative into a Grignard reagent, and then the Grignard reagent is subjected to a coupling reaction in the presence of a catalyst and a dichloropropane: (wherein A represents at least one selected from alkyl groups, alkoxy groups, alkoxymethyl groups, a vinyl group, phenyl groups and chlorine, and n represents an integer of 1 to 4).

Abstract: A process for producing biphenyl derivatives represented by formula (1), including reacting a chlorine atom of a benzene derivative represented by formula (2) with metallic magnesium to form a Grignard reagent, and coupling two molecules of the Grignard reagent with each other in the presence of a catalyst. (wherein A represents at least one member selected from the group consisting of trifluoromethyl and fluoro, and n is an integer of 1 to 4.) (wherein A represents at least one member selected from the group consisting of trifluoromethyl and fluoro, and n is an integer of 1 to 4.

Abstract: A method produces a biphenyl derivative, with an industrially high yield and excellent productivity, by use of a raw material which is low in cost and toxicity. The method for producing the biphenyl derivative represented by Formula (1) is characterized in that a chlorine atom in a benzene derivative represented by Formula (2) reacts with magnesium metal to convert the benzene derivative into a Grignard reagent, and then the Grignard reagent is subjected to a coupling reaction in the presence of a catalyst and a dichloropropane: (wherein A represents at least one selected from alkyl groups, alkoxy groups, alkoxymethyl groups, a vinyl group, phenyl groups and chlorine, and n represents an integer of 1 to 4).

Abstract: A process for producing biphenyl derivatives represented by formula (1), including reacting a chlorine atom of a benzene derivative represented by formula (2) with metallic magnesium to form a Grignard reagent, and coupling two molecules of the Grignard reagent with each other in the presence of a catalyst. (wherein A represents at least one member selected from the group consisting of trifluoromethyl and fluoro, and n is an integer of 1 to 4.) (wherein A represents at least one member selected from the group consisting of trifluoromethyl and fluoro, and n is an integer of 1 to 4.

Abstract: A tertiary phosphine compound of the formula (1): ##STR1## in which R.sup.1 and R.sup.1' are hydrogen atoms or together form --CH.dbd.CH--CH.dbd.CH--; R.sup.2 and R.sup.3 together form a group of the formula (a): ##STR2## in which --.circle-solid. represent a bond to be bonded to the R.sup.3 group, and --.smallcircle. represents a bond to be bonded to the R.sup.2 group when R.sup.1 and R.sup.1 ' together form --CH.dbd.CH--CH.dbd.CH--, or when R.sup.1 is a hydrogen atom, R.sup.2 and R.sup.3 together form --CH.dbd.CH--CH.dbd.CH-- or R.sup.2 is a hydrogen atom and R.sup.3 is a substituted or unsubstituted alkyl group, or a substituted or unsubstituted phenyl group; A.sup.1 is a 3-trifluoromethylphenyl group or a 3,5-bis(trifluoromethyl)phenyl group when R.sup.1 is a hydrogen atom and R.sup.2 and R.sup.3 together form --CH.dbd.CH--CH.dbd.CH--, or a substituted or unsubstituted phenyl group when R.sup.1 is not a hydrogen atom or when R.sup.2 and R.sup.3 do not together form --CH.dbd.CH--CH.dbd.CH--.

Abstract: A tertiary phosphine compound of the formula (1): ##STR1## wherein R.sup.1 and R.sup.2 represent independently from each other a hydrogen atom or a methyl group, or together form --CH.dbd.CH--CH.dbd.CH--; R.sup.3 is a hydrogen atom or a cycloalkyl group having 5 to 7 carbon atoms or a lower alkyl group which may be substituted with a halogen atom, a lower alkoxy group, a lower alkoxyalkoxy group or a phenyl group; X.sup.1 is a halogen atom when both R.sup.1 and R.sup.2 are hydrogen atoms, or a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group when at least one of R.sup.1 and R.sup.2 is not a hydrogen atoms; and m is an integer of 1 to 5, which is useful as a ligand of a transition metal complex that can catalyze various reactions.

Abstract: A phosphine compound represented by formula (I): ##STR1## wherein Ph represents a phenyl group; and R represents a lower alkyl group or --OR.sup.1, wherein R.sup.1 represents a hydrogen atom, a cycloalkyl group having from 5 to 7 carbon atoms, or an alkyl group having from 1 to 6 carbon atoms which may be substituted with a halogen atom, a lower alkoxy group, a lower alkoxy group-substituted lower alkoxy group, or a phenyl group, and a transition metal complex using the phosphine compound (I) as a ligand are disclosed. The transition metal complex, when used as a catalyst for various enantioselective synthesis reactions, e.g., enantioselective silylation reaction, provides a desired product in high yield at high optical purity. The absolute configuration of the product can be arbitrarily selected by selecting the optical isomer of the ligand in the transition metal complex catalyst.

Abstract: Optically active oxazoline-carboxylic acid derivatives of the formula: ##STR1## wherein R.sup.1 represents a hydrogen atom, an alkyl group having 1 to 20 carbon atoms, an alkykl group which is substituted and has 1 to 20 carbon atoms, a cycloalkyl group, a cycloalkyl group which is substituted, a phenyl group, a phenyl group which is substituted, a vinyl group, a vinyl group which is substituted, an ethynyl group or an ethynyl group which is substituted;R.sup.2 represents a lower alkyl group having 1 to 4 carbon atoms or a benzyl group;R.sup.3 represents a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, a phenyl group or a benzyl group,and a method for preparing the above compounds and derivatives thereof involving a reaction between an aldehyde and an isocyano-carboxylate in the presence of a catalyst mixture.

Abstract: An optically active arylacetic acid derivative of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and are each an hydrogen atom, a lower alkyl group or a phenyl group; and Ar is a group of the formula: ##STR2## a group of the formula: ##STR3## wherein R.sub.3 and R.sub.4 are the same or different and are each a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, a difluoromethoxy group, a trifluoromethyl group or a phenyl group is prepared in good conversion and optical yield by asymmetrically reducing an ethylenically unsaturated compound of the formula: ##STR4## wherein R.sub.1, and R.sub.2 and Ar are the same as defined above with hydrogen in the presence of a metal catalyst modified with a ligand selected from the group consisting of a specific optically active metallocenyl phosphine derivative and a specific optically active binaphthyl derivative.