Patents by Inventor Tamio Kawamura

Tamio Kawamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyprenyl sulfone derivatives and process for producing the same
    Patent number: 4613571
    Abstract: There are disclosed polyprenyl sulfone derivatives of the general formula: ##STR1## wherein n represents an integer of 1-4, R.sub.1 represents an aryl group d R.sub.2 represents a hydroxymethyl or carboxyl group. The polyprenyl sulfone derivatives are prepared by cultivating a microorganism of the genus Nocardia capable of oxidizing a compound of the general formula: ##STR2## wherein n and R.sub.1 have the same meanings as defined above, in a culture medium containing a compound of the above general formula (II), and then collecting the oxidation product from the culture mixture. The polyprenyl sulfone derivatives are useful as intermediates for preparing various useful polyprenyl compounds.
    Type: Grant
    Filed: February 21, 1984
    Date of Patent: September 23, 1986
    Assignees: Esai Co., Ltd., General Director of the Agency of Industrial Science and Technology
    Inventors: Akio Sato, Kenji Nakajima, Yoshimasa Takahara, Shizumasa Kijima, Hideaki Watanabe, Tamio Kawamura, Yasushi Nagai
  • 3-Carbamoyloxymethylcephem derivatives, and antibacterial drugs containing same
    Patent number: 4448775
    Abstract: The invention provides 3-carbamoyloxymethylcephem derivatives represented by the general formula: ##STR1## wherein R.sub.1 represents hydrogen atom or trichloroacetyl group, R.sub.2 represents hydrogen atom or methoxy group, and R.sub.3 represents hydrogen atom or hydroxyl group, or pharmaceutically acceptable salt thereof. The cephem derivatives of the invention are useful as antibacterial drugs.
    Type: Grant
    Filed: September 23, 1982
    Date of Patent: May 15, 1984
    Assignee: Eisai Co., Ltd.
    Inventors: Shigeto Negi, Yoshimasa Machida, Hiroshi Yamauchi, Isao Saito, Yoshikazu Hasagawa, Tamio Kawamura
  • Polyprenyl sulfones
    Patent number: 4449002
    Abstract: There are disclosed polyprenyl sulfone derivatives of the general formula: ##STR1## wherein n represents an integer of 1-4, R.sub.1 represents an aryl group d R.sub.2 represents a hydroxymethyl or carboxyl group. The polyprenyl sulfone derivatives are prepared by cultivating a microorganism of the genus Nocardia capable of oxidizing a compound of the general formula: ##STR2## wherein n and R.sub.1 have the same meanings as defined above, in a culture medium containing a compound of the above general formula (II), and then collecting the oxidation product from the culture mixture. The polyprenyl sulfone derivatives are useful as intermediates for preparing various useful polyprenyl compounds.
    Type: Grant
    Filed: April 14, 1982
    Date of Patent: May 15, 1984
    Assignees: Eisai Co., Ltd., General Director of the Agency of Industrial Science and Technology
    Inventors: Akio Sato, Kenji Nakajima, Yoshimasa Takahara, Shizumasa Kijima, Hideaki Watanabe, Tamio Kawamura, Yasushi Nagai
  • Process for biochemical optical resolution of alpha-tocopheral
    Patent number: 4022664
    Abstract: Novel process for biochemical optical resolution of 2DL-racemic compound of .alpha.-tocopherol ester or substances which contain the same, using culture broth, whole cell, or culture filtrate, which are obtained by cultivating microorganisms which possess an ability for hydrolysis of said ester. Beneficial advantage of the process resides in its low cost, simplicity and high resolution ratio.
    Type: Grant
    Filed: November 13, 1975
    Date of Patent: May 10, 1977
    Assignee: Eisai Co., Ltd.
    Inventors: Tamio Kawamura, Satoru Kato, Yasunori Ikeda, Noriaki Kuwana