Patents by Inventor Tammy Lawrence

Tammy Lawrence has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Coding sequence haplotype of the human BRCA1 gene
    Patent number: 6686163
    Abstract: The invention is directed to isolated coding sequences and to the protein sequences they code for. The coding sequence for BRCA1(omi4) gene is provided together with the protein sequence it codes for. The BRCA1(omi4) sequence is used for identifying an individual having an increased genetic susceptibility to breast or ovarian cancer because the patient has an inherited causative mutation in their BRCA1 gene. This invention is also related to a method of performing gene therapy with the isolated BRCA1(omi4) coding sequence and protein replacement therapy with the BRCA1(omi4) protein.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: February 3, 2004
    Assignee: Gene Logic Inc.
    Inventors: Antonette C. P. Allen, Tracy S. Angelly, Tammy Lawrence, Sheri J. Olson, Mark B. Rabin
  • Coding sequence haplotype of the human BRCA1 gene
    Publication number: 20030027166
    Abstract: The invention is directed to isolated coding sequences and to the protein sequences they code for. The coding sequence for BRCA1(omi4) gene is provided together with the protein sequence it codes for. The BRCA1(omi4) sequence is used for identifying an individual having an increased genetic susceptibility to breast or ovarian cancer because the patient has an inherited causative mutation in their BRCA1 gene. This invention is also related to a method of performing gene therapy with the isolated BRCA1(omi4) coding sequence and protein replacement therapy with the BRCA1(omi4) protein.
    Type: Application
    Filed: December 20, 2001
    Publication date: February 6, 2003
    Applicant: OncorMed Inc.
    Inventors: Antonette C.P. Allen, Tracy S. Angelly, Tammy Lawrence, Sheri J. Olson, Mark B. Rabin
  • Cancer susceptibility mutations of BRCA1
    Patent number: 6083698
    Abstract: New mutations have been found in the BRCA1 gene. The mutations are located at nucleotide numbers 421-2, 815, 903, 926, 1506, 2034, 2428, 3888, 3904, 4164, 4643, 5053, 5150, 5210, or 5396+40 of the gene sequence of BRCA1. A process for identifying a sequence variation in a BRCA1 polynucleotide sequence is disclosed. The identification process includes allele specific sequence-based assays of known sequence variations. The methods can be used for efficient, and accurate detection of a mutation in a test BRCA1 gene sample.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: July 4, 2000
    Assignee: Oncormed, Inc.
    Inventors: Sheri Jon Olson, Tracy Staton Angelly, Tammy Lawrence, Jennifer Lee Lescallett, Patricia Davis Murphy, Antonette Preisinger Allen, Denise Bernadette Thurber, Marga Belle White, Bin Zeng, Lisa K. Sadzewicz
  • Cancer susceptibility mutations of BRCA2
    Patent number: 6051379
    Abstract: New mutations have been found in the BRCA2 gene. The mutations are located at nucleotide numbers 2192, 3772, 5193, 5374, 6495 or 6909 of the published nucleotide sequence of BRCA2 gene. A process for identifying a sequence variation in a BRCA2 polynucleotide sequence is disclosed. The identification process includes allele specific sequence-based assays of known sequence variations. The methods can be used for efficient, and accurate detection of a mutation in a test BRCA2 gene sample.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: April 18, 2000
    Assignee: Oncormed, Inc.
    Inventors: Jennifer Lee Lescallett, Tammy Lawrence, Antonette Preisinger Allen, Sheri Jon Olson, Denise Bernadette Thurber, Marga Belle White