Patents by Inventor Tammy R. Dugas

Tammy R. Dugas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS, METHODS, AND DEVICES FOR SUSTAINED RELEASE OF AN AGENT
    Publication number: 20240293600
    Abstract: The present disclosure provides for compositions, methods of making the composition, and devices (e.g., vascular grafts, self-expandable stents, balloon-expandable stents, and stent-grafts) having the composition disposed thereof. The composition can include a polymer nanoparticle (e.g., charged or uncharged) made of polymers that have one or more types of agents covalently bonded to the polymer. In this regard, the one or more types of agents are not physically encapsulated by the polymer, rather are covalently bonded to the polymer that makes up the polymeric nanoparticle. In another aspect, an agent can also be encapsulated in the polymer of the polymeric nanoparticle. In another embodiment, the composition includes two types of polymeric nanoparticles, where a first polymeric nanoparticle has at least one agent covalently bonded to the polymer of the first polymeric nanoparticle and where the composition can also include a second polymeric nanoparticle encapsulating an agent.
    Type: Application
    Filed: June 21, 2022
    Publication date: September 5, 2024
    Inventors: Tammy R. Dugas, Cristina Sabliov, Carlos Astete
  • Coated devices and method of making coated devices that reduce smooth muscle cell proliferation and platelet activity
    Patent number: 8992603
    Abstract: The present invention relates generally to the maintenance of blow flood using drug eluting stents and/or other coated medical devices to increased length of time of blood flow. Further, the present invention relates to drug-releasing coated devices for reducing smooth muscle cell proliferation and platelet activity to further limit restenosis utilizing resveratrol and quercetin, polyphenols that are linked to the cardioprotection of red wine consumption. The present invention also provides products and methods for treating or preventing atherosclerosis, stenosis, restenosis, smooth muscle cell proliferation, platelet cell activation and other clotting mechanisms, occlusive disease, or other abnormal lumenal cellular proliferation condition in a location within the body of a patient.
    Type: Grant
    Filed: October 2, 2012
    Date of Patent: March 31, 2015
    Assignees: Nanocopoeia, Inc., Louisiana State University Health Sciences Center Office of Research
    Inventors: Tammy R. Dugas, Alok Khandelwal, James John Kleinedler, John Devlin Foley
  • Coated devices and method of making coated devices that reduce smooth muscle cell proliferation and platelet activity
    Patent number: 8992471
    Abstract: The present invention relates generally to the maintenance of blow flood using drug eluting stents and/or other coated medical devices to increased length of time of blood flow. Further, the present invention relates to drug-releasing coated devices for reducing smooth muscle cell proliferation and platelet activity to further limit restenosis utilizing resveratrol and quercetin, polyphenols that are linked to the cardioprotection of red wine consumption. The present invention also provides products and methods for treating or preventing atherosclerosis, stenosis, restenosis, smooth muscle cell proliferation, platelet cell activation and other clotting mechanisms, occlusive disease, or other abnormal lumenal cellular proliferation condition in a location within the body of a patient.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: March 31, 2015
    Assignees: Nanocopoeia, Inc., Louisiana State University Health Sciences Center Office of Research
    Inventors: Tammy R. Dugas, Alok Khandelwal, James John Kleinedler, III, John Devlin Foley
  • COATED DEVICES AND METHOD OF MAKING COATED DEVICES THAT REDUCE SMOOTH MUSCLE CELL PROLIFERATION AND PLATELET ACTIVITY
    Publication number: 20100331965
    Abstract: The present invention relates generally to the maintenance of blow flood using drug eluting stents and/or other coated medical devices to increased length of time of blood flow. Further, the present invention relates to drug-releasing coated devices for reducing smooth muscle cell proliferation and platelet activity to further limit restenosis utilizing resveratrol and quercetin, polyphenols that are linked to the cardioprotection of red wine consumption. The present invention also provides products and methods for treating or preventing atherosclerosis, stenosis, restenosis, smooth muscle cell proliferation, platelet cell activation and other clotting mechanisms, occlusive disease, or other abnormal lumenal cellular proliferation condition in a location within the body of a patient.
    Type: Application
    Filed: November 5, 2008
    Publication date: December 30, 2010
    Applicant: NANOCOPOEIA, INC.
    Inventors: Tammy R. Dugas, Alok Khandelwal, James John Kleinedler, III, John Devlin Foley