Patents by Inventor Tan Thanh Dinh

Tan Thanh Dinh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for quantitative and qualitative analyses of phospholipids using one-dimensional thin layer chromatography
    Patent number: 6783988
    Abstract: A highly sensitive and specific method for the detection and quantification of lipids is provided. Specifically, methods for the simultaneous detection and quantification of phospholipids extracted from mammalian tissues is described. The analytical methods provided disclose a modified one-dimensional thin-layer chromatography technique specifically developed to rapidly and accurantely detect and quantify phospholipids from mammalian cardiac tissues.
    Type: Grant
    Filed: October 19, 2000
    Date of Patent: August 31, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tan Thanh Dinh, Patrice Tremble, Crystal M. Cunanan, Christine May Cabiling
  • Treatment of tissue, instruments and work surfaces to remove infectious agents
    Publication number: 20030050276
    Abstract: The present invention provides methods of inactivating and removing infectious agents from tissues of use in bioprosthetic devices. The methods include the removal and blockage of binding sites on the tissues for the infectious agents. Also provided are methods for blocking a site on an infectious agent that binds to a site on the tissue.
    Type: Application
    Filed: August 15, 2001
    Publication date: March 13, 2003
    Inventors: Crystal M. Cunanan, Tan Thanh Dinh, Christine Loshbaugh, H. Chris Sarner, Michael N. Helmus
  • Methods for preparation of bioprosthetic tissue and implantable devices comprising such bioprosthetic tissue
    Publication number: 20020137024
    Abstract: The present invention provides methods of inactivating and removing infectious agents from tissues of use in bioprosthetic devices. The methods include the removal and blockage of binding sites on the tissues for the infectious agents. Also provided are methods for blocking a site on an infectious agent that binds to a site on the tissue. The invention also provides a method for preventing or reducing the calcification of a bioprosthetic tissue. The method includes removing or blocking a phospholipid calcium nucleation site from the tissue.
    Type: Application
    Filed: November 1, 2001
    Publication date: September 26, 2002
    Inventors: Crystal M. Cunanan, Tan Thanh Dinh, Christine Loshbaugh, H. Chris Sarner, Michael N. Helmus, Christine M. Cabiling
  • Method for inhibiting calcification of aldehyde-fixed bioprosthetic materials
    Patent number: 6008292
    Abstract: A method for preparing collagenous biological tissues for use as implantable bioprosthetic material, and articles prepared thereby. The method generally comprises the steps of a) contacting the tissue with an aldehyde fixative to effect cross-linking of the connective tissue protein(s) and subsequently b) contacting the tissue with a polyglycidyl ether. The treatment of the crosslinked tissue with the polyglycidyl ether serves to mitigate the tissue's propensity to undergo calcification following implantation in the body.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: December 28, 1999
    Assignee: Baxter International Inc.
    Inventors: Catherine Ting Lee, Jun Yang, Tan Thanh Dinh, Ernest H. Pfadenhauer
  • Method for inhibiting chymopapain and papain enzyme activity with polysaccharides of animal origin
    Patent number: 5670358
    Abstract: The activities of chymopapain or papain in enzyme mixtures are inhibited by the addition of glycogen, hyaluronic acid, or desulfated heparin. The process for isolating viable hepatocytes or pancreatic cells by treatment with papain or chymopapain is improved by terminating the treatment by inhibiting the reaction with these polysaccharides. Similarly, the process for removing undesired tissue by treatment with papain or chymopapain is improved by terminating the treatment by inhibiting the reaction with these polysaccharides.
    Type: Grant
    Filed: October 19, 1995
    Date of Patent: September 23, 1997
    Assignee: Baxter International Inc.
    Inventors: Catherine T. Lee, Cynthia Zerfass, Tan Thanh Dinh, Minh T. Ma