Patents by Inventor Tanenao Eto

Tanenao Eto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adrenomedullin
    Patent number: 5910416
    Abstract: Adrenomedullin which is a novel peptide having a hypotensive effect; proadrenomedullin N-terminal 20 peptide (proAM-N20) corresponding to an amino acid sequence of an N-terminus of proadrenomedullin, having a catecholamine secretion inhibitory effect; proadrenomedullin N-terminal 10-20 peptide (proAM-N(10-20)) having a Na channel inhibitory effect, and a gene encoding these peptides are provided. In addition, according to the present invention, these peptides in a sample containing adrenomdullin or proAM-N20 in an unknown amount can be quantified by using an antibody against adrenomedullin, proAM-N20, or its fragment.
    Type: Grant
    Filed: January 7, 1998
    Date of Patent: June 8, 1999
    Assignees: Shionogi & Co., Ltd., Kenji Kangawa
    Inventors: Kazuo Kitamura, Kenji Kangawa, Hisayuki Matsuo, Tanenao Eto
  • Antibodies to adrenomedullin
    Patent number: 5837823
    Abstract: According to the present invention, adrenomedullin which is a novel peptide having a hypotensive effect; proadrenomedullin N-terminal 20 peptide (proAM-N20) corresponding to an amino acid sequence of an N-terminus of proadrenomedullin, having a catecholamine secretion inhibitory effect; proadrenomedullin N-terminal 10-20 peptide (proAM-N(10-20)) having a Na channel inhibitory effect, and a gene encoding these peptides are provided. In addition, according to the present invention, these peptides in a sample containing adrenomdullin or proAM-N20 in an unknown amount can be quantified by using an antibody against adrenomedullin, proAM-N20, or its fragment.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 17, 1998
    Assignees: Shinonogi & Co., Ltd., Kenji Kangawa
    Inventors: Kazuo Kitamura, Kenji Kangawa, Hisayuki Matsuo, Tanenao Eto
  • DNA encoding adrenomedullin
    Patent number: 5830703
    Abstract: According to the present invention, adrenomedullin which is a novel peptide having a hypotensive effect; proadrenomedullin N-terminal 20 peptide (proAM-N20) corresponding to an amino acid sequence of an N-terminus of proadrenomedullin, having a catecholamine secretion inhibitory effect; proadrenomedullin N-terminal 10-20 peptide (proAM-N(10-20)) having a Na channel inhibitory effect, and a gene encoding these peptides are provided. In addition, according to the present invention, these peptides in a sample containing adrenomdullin or proAM-N20 in an unknown amount can be quantified by using an antibody against adrenomedullin, proAM-N20, or its fragment.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: November 3, 1998
    Assignees: Shionogi & Co., Ltd., Kenji Kangawa
    Inventors: Kazuo Kitamura, Kenji Kangawa, Hisayuki Matsuo, Tanenao Eto
  • Adrenomedullin
    Patent number: 5639855
    Abstract: According to the present invention, adrenomedullin which is a novel peptide having a hypotensive effect; proadrenomedullin N-terminal 20 peptide (proAM-N20) corresponding to an amino acid sequence of an N-terminus of proadrenomedullin, having a catecholamine secretion inhibitory effect; proadrenomedullin N-terminal 10-20 peptide (proAM-N(10-20)) having a Na channel inhibitory effect, and a gene encoding these peptides are provided. In addition, according to the present invention, these peptides in a sample containing adrenomedullin or proAM-N20 in an unknown amount can be quantified by using an antibody against adrenomedullin, proAM-N20, or its fragment.
    Type: Grant
    Filed: April 26, 1994
    Date of Patent: June 17, 1997
    Assignees: Shionogi & Co., Ltd., Kenji Kangawa
    Inventors: Kazuo Kitamura, Kenji Kangawa, Hisayuki Matsuo, Tanenao Eto