Patents by Inventor Tang J. Wang

Tang J. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and device for detecting prostate specific antigen (PSA)
    Patent number: 7300761
    Abstract: An immunoassay device and assay to detect an antigen, such as PSA, in a biological sample. The device comprises a solid support having multiple reaction zones containing capture antibodies directed to the antigen. Exposure of a test sample to a mixture of incubation antibodies with known and different concentrations prior to exposure to the capture antibodies in the reaction zones facilitates determination of a range of concentrations of the antigen.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: November 27, 2007
    Inventor: Tang J. Wang
  • Methods and device for detecting prostate specific antigen (PSA)
    Publication number: 20040214254
    Abstract: An immunoassay device and assay to detect an antigen, such as PSA, in a biological sample. The device comprises a solid support having multiple reaction zones containing capture antibodies directed to the antigen. Exposure of a test sample to a mixture of incubation antibodies with known and different concentrations prior to exposure to the capture antibodies in the reaction zones facilitates determination of a range of concentrations of the antigen.
    Type: Application
    Filed: May 20, 2004
    Publication date: October 28, 2004
    Inventor: Tang J. Wang
  • Methods and device for detecting prostate specific antigen (PSA)
    Patent number: 6764825
    Abstract: An immunoassay device and assay to detect an antigen, such as PSA, in a biological sample. The device comprises a solid support having multiple reaction zones containing capture antibodies directed to the antigen. Exposure of a test sample to a mixture of incubation antibodies with known and different concentrations prior to exposure to the capture antibodies in the reaction zones facilitates determination of a range of concentrations of the antigen.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: July 20, 2004
    Inventor: Tang J. Wang
  • Monoclonal antibodies specific for the PSA-ACT complex
    Patent number: 5856182
    Abstract: Monoclonal antibodies have been developed which specifically bind the PSA-ACT complex without significant cross-reactivity with PSA, ACT or CG-ACT. The antibodies were generated using a unique immunogen comprising a PSA-ACT complex having bound to monoclonal antibodies against PSA and monoclonal antibodies against ACT. It is theorized that the antibodies against PSA and ACT block immunodominant sites on the PSA-ACT complex. The antibodies generated against the unique immunogen specifically bind the PSA-ACT complex, but have no significant cross-reactivity with either PSA or ACT. The monoclonal antibodies of the present invention can be used in immunoassays to specifically detect PSA-ACT in a sample.
    Type: Grant
    Filed: November 18, 1996
    Date of Patent: January 5, 1999
    Assignee: Beckman Coulter, Inc.
    Inventors: Kristine Kuus-Reichel, Harry Jay Linton, Janice K. Payne, Tang J. Wang