Abstract: The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of human erythroviruses, such as the B19, V9, and A6 genotype, in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved region of the erythrovirus genomes. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention.

Abstract: Disclosed herein are methods for assaying the phenotype of a bioactive molecule in the presence and absence of compounds that are known inhibitors of the phenotypable activity of the bioactive molecule. Also disclosed are methods for discovering compounds that can inhibit the phenotypable activity of a bioactive molecule. The methods and assays of the present invention are useful in developing and monitoring a chemotherapy regimen for a patient, to detect or prevent the emergence of a drug resistant phenotype.