Patents by Inventor Tanguy Fortin
Tanguy Fortin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240141406Abstract: A method for quantifying at least one microorganism group via at least one mass spectrometry analysis. The method includes at least one separation and fragmentation step. The method moreover includes a step that involves measuring the amount of at least one representative peptide or at least one protein representing the microorganism group. The at least one representative peptide or the at least one protein is obtained after the at least one separation and fragmentation step and serves as a quantification marker(s). The amount of the quantification marker(s) is directly correlatable to the amount of the at least one microorganism group.Type: ApplicationFiled: January 10, 2024Publication date: May 2, 2024Applicant: BIOMÉRIEUXInventors: Chloé BARDET, Tiphaine CECCHINI, Yannick CHARRETIER, Jean-Philippe CHARRIER, Christelle COMPAGNON, Tanguy FORTIN
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Patent number: 11898192Abstract: A method for quantifying at least one microorganism group via at least one mass spectrometry analysis. The method includes at least one separation and fragmentation step. The method moreover includes a step that involves measuring the amount of at least one representative peptide or at least one protein representing the microorganism group. The at least one representative peptide or the at least one protein is obtained after the at least one separation and fragmentation step and serves as a quantification marker(s). The amount of the quantification marker(s) is directly correlatable to the amount of the at least one microorganism group.Type: GrantFiled: August 11, 2015Date of Patent: February 13, 2024Assignee: BIOMÉRIEUXInventors: Chloé Bardet, Tiphaine Cecchini, Yannick Charretier, Jean-Philippe Charrier, Christelle Compagnon, Tanguy Fortin
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Patent number: 11237084Abstract: The present invention concerns the preparation of solutions, particularly for implementing analytical methods, in particular by spectrometry, particularly for producing standard solutions which are useful, for example, for calibrating spectrometers or for implementing diagnostic methods. It allows the implementation of an easy process for preparing such standard solutions.Type: GrantFiled: March 23, 2017Date of Patent: February 1, 2022Assignee: ANAQUANTInventors: Tanguy Fortin, Chloe Bardet, Jordane Biarc
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Patent number: 10670602Abstract: The invention relates to a method for detecting a colorectal lesion likely to evolve into invasive colorectal cancer, in a patient, by determining the presence of Liver Fatty Acid-Binding Protein (LFABP), in a biological sample of the patient, distant form the lesion.Type: GrantFiled: January 31, 2014Date of Patent: June 2, 2020Assignees: BIOMERIEUX, CHU DE DIJONInventors: Jean-Philippe Charrier, Genevieve Choquet-Kastylevsky, Tanguy Fortin, Hader Haidous, Jerome Lemoine, Arnaud Salvador, Jean Faivre
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Patent number: 10466255Abstract: A method for predicting the risk of developing a disseminated infection in a patient admitted to intensive care having no clinical symptoms of such infection includes: determining a first dose of gelsolin G1 in a biological sample from the patient originating from a first sample taken at time T1, carried out between the day of intensive care admission and 48 hours afterward; determining a second dose of gelsolin G2 in a biological sample from the patient originating from a second sample taken at time T2, carried out two to three days after the first sampling; calculating the variation between the dose of gelsolin G2 and the dose of gelsolin G1, giving a ? value; and comparing the ? value to a threshold value S determined beforehand from two patient populations admitted to intensive care, one not having developed a disseminated infection and the other having developed such an infection.Type: GrantFiled: May 11, 2016Date of Patent: November 5, 2019Assignees: BIOMERIEUX, HOSPICES CIVILS DE LYON, CENTRE HOSPITALIER UNIVERSITAIRE DE NANTESInventors: Bernard Allaouchiche, Karim Asehnoune, Marilyne Dupin, Tanguy Fortin, Aurélie Gouel-Cheron, Audrey Larue-Triolet, Guillaume Monneret, Alexandre Pachot, Sylvie Pons, Antoine Roquilly, Fabienne Venet
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Publication number: 20190101476Abstract: The present invention concerns the preparation of solutions, particularly for implementing analytical methods, in particular by spectrometry, particularly for producing standard solutions which are useful, for example, for calibrating spectrometers or for implementing diagnostic methods. It allows the implementation of an easy process for preparing such standard solutions.Type: ApplicationFiled: March 23, 2017Publication date: April 4, 2019Inventors: Tanguy FORTIN, Chloe BARDET, Jordane BIARC
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Publication number: 20180095094Abstract: A method for predicting the risk of developing a disseminated infection in a patient admitted to intensive care having no clinical symptoms of such infection includes: determining a first dose of gelsolin G1 in a biological sample from said patient originating from a first sample taken at time T1, carried out between the day of intensive care admission and 48 hours afterward; determining a second dose of gelsolin G2 in a biological sample from said patient originating from a second sample taken at time T2, carried out two to three days after the first sampling; calculating the variation between the dose of gelsolin G2 and the dose of gelsolin G1, giving a ? value; and comparing the ? value to a threshold value S determined beforehand from two patient populations admitted to intensive care, one not having developed a disseminated infection and the other having developed such an infection.Type: ApplicationFiled: May 11, 2016Publication date: April 5, 2018Applicants: BIOMÉRIEUX, HOSPICES CIVILS DE LYON, CENTRE HOSPITALIER UNIVERSITAIRE DE NANTESInventors: Bernard ALLAOUCHICHE, Karim ASEHNOUNE, Marilyne DUPIN, Tanguy FORTIN, Aurélie GOUEL-CHERON, Audrey LARUE-TRIOLET, Guillaume MONNERET, Alexandre PACHOT, Sylvie PONS, Antoine ROQUILLY, Fabienne VENET
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Publication number: 20170275667Abstract: A method for quantifying at least one microorganism group via at least one mass spectrometry analysis. The method includes at least one separation and fragmentation step. The method moreover includes a step that involves measuring the amount of at least one representative peptide or at least one protein representing the microorganism group. The at least one representative peptide or the at least one protein is obtained after the at least one separation and fragmentation step and serves as a quantification marker(s). The amount of the quantification marker(s) is directly correlatable to the amount of the at least one microorganism group.Type: ApplicationFiled: August 11, 2015Publication date: September 28, 2017Applicant: BIOMÉRIEUXInventors: Chloé BARDET, Tiphaine CECCHINI, Yannick CHARRETIER, Jean-Philippe CHARRIER, Christelle COMPAGNON, Tanguy FORTIN
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Publication number: 20150362494Abstract: The invention relates to a method for detecting a colorectal lesion likely to evolve into invasive colorectal cancer, in a patient, by determining the presence of Liver Fatty Acid-Binding Protein (LFABP), in a biological sample of the patient, distant form the lesion.Type: ApplicationFiled: January 31, 2014Publication date: December 17, 2015Inventors: Jean-Philippe CHARRIER, Genevieve CHOQUET-KASTYLEVSKY, Tanguy FORTIN, Hader HAIDOUS, Jerome LEMOINE, Arnaud SALVADOR, Jean FAIVRE
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Patent number: 9170263Abstract: The present invention relates to a method for the quantitative detection of a target protein in a sample, in which the second-generation fragment ions are detected for providing a series of quantitative measurements, at least one of which is correlated to the amount of proteotypic peptide generated and to the amount of target protein in the sample, characterized in that the selected first-generation fragment ion having a mass (m/z)2 is a doubly-charged peptide having a proline and/or a histidine in position 1.Type: GrantFiled: May 21, 2010Date of Patent: October 27, 2015Assignees: bioMerieux, UNIVERSITE CLAUDE BERNARD LYON I, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Jérôme Lemoine, Arnaud Salvador, Jean-Philippe Charrier, Tanguy Fortin
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Patent number: 9018580Abstract: A method for detecting at least one target molecule in a sample by mass spectrometry, comprising ionizing the molecules of the sample and then conducting the following steps (i) and (ii) n times, n being equal to 0, 1, 2, 3 or 4: (i) at least one ion obtained in the preceding step is selected, according to the target molecule, in a mass analyzer, and (ii) the ion thus selected is fragmented in a fragmentation cell; trapping at least two different sampled ions, when n is zero, or when n is other than zero, in a mass analyzer, the at least two ions thus trapped having a mass-to-charge ratio m/z characteristic of the target molecule; ejecting the trapped ions from the mass analyzer; and detecting the ejected ions ejected by means of a detection device. The method is characterized in that the characteristic ions are ejected simultaneously and detected simultaneously.Type: GrantFiled: September 15, 2010Date of Patent: April 28, 2015Assignees: bioMerieux, Universite Claude Bernard Lyon I, Centre National de la Recherche ScientifiqueInventors: Jéröme Lemoine, Arnaud Salvador, Jean-Philippe Charrier, Tanguy Fortin, Philippe Dugourd
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Publication number: 20120208224Abstract: The present invention relates to a method for the quantitative detection of a target protein in a sample, in which the second-generation fragment ions are detected for providing a series of quantitative measurements, at least one of which is correlated to the amount of proteotypic peptide generated and to the amount of target protein in the sample, characterized in that the selected first-generation fragment ion having a mass (m/z)2 is a doubly-charged peptide having a proline and/or a histidine in position 1.Type: ApplicationFiled: May 21, 2010Publication date: August 16, 2012Applicants: bioMerieux, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON IInventors: Jérôme Lemoine, Arnaud Salvador, Jean-Philippe Charrier, Tanguy Fortin
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Publication number: 20120205535Abstract: A method for detecting at least one target molecule in a sample by mass spectrometry, comprising ionizing the molecules of the sample and then conducting the following steps (i) and (ii) n times, n being equal to 0, 1, 2, 3 or 4: (i) at least one ion obtained in the preceding step is selected, according to the target molecule, in a mass analyser, and (ii) the ion thus selected is fragmented in a fragmentation cell; trapping at least two different sampled ions, when n is zero, or when n is other than zero, in a mass analyser, the at least two ions thus trapped having a mass-to-charge ratio m/z characteristic of the target molecule; ejecting the trapped ions from the mass analyser; and detecting the ejected ions ejected by means of a detection device. The method is characterized in that the characteristic ions are ejected simultaneously and detected simultaneously.Type: ApplicationFiled: September 15, 2010Publication date: August 16, 2012Applicants: BioMerieux, Centre National De La Recherche Scientifique, Universite Claude Bernard Lyon IInventors: Jéröme Lemoine, Arnaud Salvador, Jean-Philippe Charrier, Tanguy Fortin, Philippe Dugourd