Patents by Inventor Tania Kastelic

Tania Kastelic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11576892
    Abstract: The present disclosure provides for compounds useful for the treatment or prevention of disorders with an etiology associated with or comprising excessive cytokine or chemokine release. The compounds are also useful for the treatment of cancer, inflammatory disorders and disorders associated with an increased stability or translation of mRNA which has an mRNA instability sequence.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: February 14, 2023
    Assignee: NOVATION PHARMACEUTICALS INC.
    Inventors: Dominique J. Cheneval, Tania Kastelic
  • Publication number: 20220016071
    Abstract: The present disclosure provides for compounds useful for the treatment or prevention of disorders with an etiology associated with or comprising excessive cytokine or chemokine release. The compounds are also useful for the treatment of cancer, inflammatory disorders and disorders associated with an increased stability or translation of mRNA which has an mRNA instability sequence.
    Type: Application
    Filed: August 17, 2016
    Publication date: January 20, 2022
    Inventors: Dominique J. Cheneval, Tania Kastelic
  • Publication number: 20150176088
    Abstract: The present invention relates to an assay for the identification of biological active compounds, in particular to a reporter gene assay for the identification of compounds, which have an effect on mRNA stability. More particularly, the present invention relates to a reporter gene expression system and cell lines comprising said expression system. The invention further relates to compounds which destabilise mRNA.
    Type: Application
    Filed: December 10, 2014
    Publication date: June 25, 2015
    Inventors: Tania KASTELIC, Dominique Cheneval
  • Patent number: 7598079
    Abstract: The present invention relates to an assay for the identification of biologically active compounds, in particular to a reporter gene assay for the identification of compounds, which have an effect on mRNA stability. More particularly, the present invention relates to a reporter gene expression system and cell lines comprising said expression system. The invention further relates to compounds which destabilize mRNA.
    Type: Grant
    Filed: April 1, 2004
    Date of Patent: October 6, 2009
    Assignee: Novation Pharmaceuticals, Inc.
    Inventors: Tania Kastelic, Dominique Cheneval
  • Publication number: 20090068654
    Abstract: The present invention relates to an assay for the identification of biologically active compounds, in particular to a reporter gene assay for the identification of compounds, which have an effect on mRNA stability. More particularly, the present invention relates to a reporter gene expression system and cell lines comprising said expression system. The invention further relates to compounds which destabilise mRNA.
    Type: Application
    Filed: October 5, 2007
    Publication date: March 12, 2009
    Applicant: Novation Pharmaceuticals Inc.
    Inventors: Tania Kastelic, Dominique Cheneval
  • Publication number: 20050049202
    Abstract: The present invention is provides benzoic acid derivatives and uses thereof.
    Type: Application
    Filed: September 21, 2001
    Publication date: March 3, 2005
    Inventors: Tania Kastelic, Dominique Cheneval, Albert Leutwiler
  • Publication number: 20040231007
    Abstract: The present invention relates to an assay for the identification of biologically active compounds, in particular to a reporter gene assay for the identification of compounds, which have an effect on mRNA stability. More particularly, the present invention relates to a reporter gene expression system and cell lines comprising said expression system. The invention further relates to compounds which destabilise mRNA.
    Type: Application
    Filed: April 1, 2004
    Publication date: November 18, 2004
    Applicant: Novation Pharmaceuticals Inc.
    Inventors: Tania Kastelic, Dominique Cheneval
  • Patent number: 6635671
    Abstract: Compounds which induce degradation of mRNA which contains one or more mRNA instability sequences are provided for use as pharmaceuticals, e.g. for use in the prophylaxis or treatment of diseases and medical conditions in general having an etiology associated with the increased or prolonged stability of mRNAs which contain one or more mRNA instability sequences, and which on prolonged or inappropriate expression typically give rise to undesirable effects, e.g. cancer cell growth or an unwanted inflammatory response.
    Type: Grant
    Filed: August 15, 2001
    Date of Patent: October 21, 2003
    Assignee: Novation Pharmaceuticals Inc.
    Inventors: Tania Kastelic, Dominique Cheneval, Stephan Ruetz