Patents by Inventor Tania Melina RODRÍGUEZ

Tania Melina RODRÍGUEZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TGF- RECEPTOR II ISOFORM, FUSION PEPTIDE, METHODS OF TREATMENT AND METHODS IN VITRO
    Publication number: 20210371502
    Abstract: An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2. A fusion peptide is provided comprising an isoform of the TGF beta II receptor fused to a ligand, wherein a vector comprising the fusion peptide is used to treat cancer and/or hepatic fibrosis. An antibody binding the soluble isoform of the TGF beta II receptor is provided. The antibody binds the amino acid sequence shown in SEQ ID No. 12 and is used in in vitro methods.
    Type: Application
    Filed: April 12, 2021
    Publication date: December 2, 2021
    Applicants: Consejo Nacional de Investigaciones Científicas y Técnicas, FUNDACIÓN ARTICULAR, INIS BIOTECH LLC
    Inventors: Ana ROMO, Anabela Belen LA COLLA, Matias Adan PREISEGGER, Marcela Soledad BERTOLIO, Ricardo Alfredo DEWEY, Pamela Daiana VAZQUEZ, Andrea Nancy CHISARI, Tania Melina RODRIGUEZ, Benito Jorge VELASCO ZAMORA
  • TGF-receptor II isoform, fusion peptide, methods of treatment and methods in vitro
    Patent number: 11072647
    Abstract: An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2. A fusion peptide is provided comprising an isoform of the TGF beta II receptor fused to a ligand, wherein a vector comprising the fusion peptide is used to treat cancer and/or hepatic fibrosis. An antibody binding the soluble isoform of the TGF beta II receptor is provided. The antibody binds the amino acid sequence shown in SEQ ID No. 12 and is used in in vitro methods.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: July 27, 2021
    Assignees: Onsejo Nacional DE Investigation Cientiticay Tecnica, Fundocion Articula
    Inventors: Ana Romo, Anabela Belen La Colla, Matias Adan Preisegger, Marcela Soledad Bertolio, Ricardo Alfredo Dewey, Pamela Daiana Vazquez, Andrea Nancy Chisari, Tania Melina Rodriguez, Benito Jorge Velasco Zamora
  • TGF- RECEPTOR II ISOFORM, FUSION PEPTIDE, METHODS OF TREATMENT AND METHODS IN VITRO
    Publication number: 20190112352
    Abstract: An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2. A fusion peptide is provided comprising an isoform of the TGF beta II receptor fused to a ligand, wherein a vector comprising the fusion peptide is used to treat cancer and/or hepatic fibrosis. An antibody binding the soluble isoform of the TGF beta II receptor is provided. The antibody binds the amino acid sequence shown in SEQ ID No. 12 and is used in in vitro methods.
    Type: Application
    Filed: October 29, 2018
    Publication date: April 18, 2019
    Inventors: Ana ROMO, Anabela Belen LA COLLA, Matias Adan PREISEGGER, Marcela Soledad BERTOLIO, Ricardo Alfredo DEWEY, Pamela Daiana VELAZQUEZ, Andrea Nancy CHISARI, Tania Melina RODRIGUEZ, Benito Jorge VELASCO ZAMORA
  • Isoform of the TGF-beta receptor II
    Patent number: 10233227
    Abstract: An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain; wherein the isoform is a TGF?-1 agonist. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: March 19, 2019
    Assignees: CONSEJO Nacional de Investigaciones Cientificas y Tecnicas, FUNDACION ARTICULAR, INIS BIOTECH LLC
    Inventors: Ricardo Alfredo Dewey, Benito Jorge Velasco Zamora, Tania Melina Rodríguez, Alejandra Carrea, Andrea Nancy Chisari, Marcelo Javier Perone
  • ISOFORM OF THE TGF-BETA RECEPTOR II
    Publication number: 20160318989
    Abstract: An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain; wherein the isoform is a TGF?-1 agonist. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 3, 2016
    Applicants: Consejo Nacional de Investigaciones Científicas y Técnicas, FUNDACIÓN ARTICULAR, INIS BIOTECH LLC
    Inventors: Ricardo Alfredo DEWEY, Benito Jorge VELASCO ZAMORA, Tania Melina RODRÍGUEZ, Alejandra CARREA, Andrea Nancy CHISARI, Marcelo Javier PERONE