Abstract: The present invention provides an oral tablet comprising glatiramer acetate in an amount from about 10 percent to about 60 percent by weight and one or more gel forming agents in a total amount up to about 90 percent by weight. The present invention also provides a method of delivering glatiramer acetate across a buccal membrane comprising orally administering an oral tablet of any one of the embodiments.

Abstract: This invention provides a transdermal patch comprising a) a backing layer; b) a liner; c) optionally, a highly porous membrane; and d) a pharmaceutical composition comprising: (i) optionally, a pressure sensitive adhesive in an amount of up to about 95 wt % of the pharmaceutical composition, (ii) laquinimod in an amount of about 0.1-20 wt % of the pharmaceutical composition, and (iii) optionally, one or more permeation enhancers in a total amount of up to about 70 wt % of the pharmaceutical composition. This invention also provides a method for delivering laquinimod across the skin of the subject and for treating a human subject afflicted with a form of multiple sclerosis comprising administering to the skin of the subject a transdermal patch as described herein. This invention further provides a transdermal patch as described herein for use in treating a human subject afflicted with a form of multiple sclerosis.

Abstract: The present invention provides an oral patch comprising: a liner; and a film composition thereon, the film composition comprising glatiramer acetate in an amount from about 10 percent to about 40 percent by weight of the film composition and one or more film forming agents in a total amount from about 40 percent to about 80 percent by weight of the film composition.