Abstract: A pharmaceutical container includes an inner surface and an outer surface. At least part of the inner surface is coated with a coating to form a coated inner surface. On the coated inner surface the container, based on negative mode Time-of-Flight-Secondary Ion Mass Spectrometry (ToF-SIMS) data, has a relative lipid nanoparticle (LNP)-incubated Multivariate Curve Resolution (MCR) score ratio of lipid factor1 of less than 0.67.

Abstract: A pharmaceutical container for drug delivery includes a barrel configured to slidably receive a stopper, the stopper having a proximal end suitable for contacting a plunger rod and a distal end suitable for contacting a pharmaceutical composition, the stopper having a circumferential surface partially contacting an inner surface of the barrel, a surface roughness of the inner surface of the barrel declines from the stopper's start position to its end position by at least 3% of at least one of Ra roughness or Rms roughness, the inner surface of the barrel having a surface roughness Ra of less than 100 nm.

Abstract: A pharmaceutical container for drug delivery includes a barrel configured to slidably receive a stopper. The stopper has a proximal end suitable for contacting a plunger rod and a distal end suitable for contacting a pharmaceutical composition. The stopper has a circumferential surface partially contacting an inner surface of the barrel. A surface roughness of the inner surface of the barrel declines from the stopper's start position to its end position by at least 3% of at least one of Ra roughness or Rms roughness.

Abstract: A coated glass container includes: a glass surface; and a coating that coats at least part of the glass surface to form a coated glass surface. The coating includes at least one layer. The coated glass container fulfills the following parameter: leaching of [Na] ions after an alkaline treatment is 10 mg/l or less [Na] ions.

Abstract: A coated glass element includes: a glass surface and a coating that coats at least part of the glass surface. The coating has at least one layer. The at least one layer of the coating fulfills the following parameter: [Al+]80/[Al+]20?1.8. [Al+]20 are counts of [Al+] ions, measured by a time-of-flight secondary ion mass spectrometry (TOF-SIMS), at 20% of a time a sputter gun beam needs to reach the glass surface and [Al+]80 are counts of [Al+] ions, measured by a TOF-SIMS, at 80% of a time a sputter gun beam needs to reach the glass surface.

Abstract: A coated glass element includes: a glass surface; and a coating that coats at least part of the glass surface. The coating includes at least one layer. The at least one layer of the coating fulfills the following parameter: [Si2C5H15O2?]20/[Si2C5H15O2?]80?1.0. [Si2C5H15O2?]20 are counts of [Si2C5H15O2] ions, measured by a time-of-flight secondary ion mass spectrometry (TOF-SIMS), at 20% of a time a sputter gun beam needs to reach the glass surface and [Si2C5H15O2?]80 are counts of [Si2C5H15O2?]80 ions, measured by a TOF-SIMS, at 80% of a time a sputter gun beam needs to reach the glass surface.

Abstract: A pharmaceutical container for drug delivery includes a barrel configured to slidably receive a stopper. The stopper has a proximal end suitable for contacting a plunger rod and a distal end suitable for contacting a pharmaceutical composition. The stopper has a circumferential surface partially contacting an inner surface of the barrel. A surface roughness of the inner surface of the barrel declines from the stopper's start position to its end position by at least 3% of at least one of Ra roughness or Rms roughness.

Abstract: A composite material for a pharmaceutical packaging is provided that includes a substrate and a protective layer. The substrate has a contact region in contact with the protective layer. The contact region includes a contact area between the substrate and the protective layer and a region of the substrate close to the surface. The substrate is made of glass or of a cyclic olefin polymer or a cyclic olefin copolymer, while the protective layer is made of ceramic material. The substrate in the contact region is different from the substrate outside the contact region.

Abstract: A coated glass ceramic cooking plate is provided, which has a multilayer coating on its lower surface. The multilayer coating includes a metallic layer of an alloy including components chromium, iron, nickel, and silicon. The silicon content of the alloy is at least 2 atomic percent. This metallic layer is covered by a barrier layer in form of an oxide of an alloy including components chromium, iron, nickel, and silicon, also with a silicon content of at least 2 atomic percent. The molar content of oxygen of the barrier layer is greater by at least a factor of 10 than that of the metallic layer.

Abstract: A composite material for a pharmaceutical packaging is provided that includes a substrate and a protective layer. The substrate has a contact region in contact with the protective layer. The contact region includes a contact area between the substrate and the protective layer and a region of the substrate close to the surface. The substrate is made of glass or of a cyclic olefin polymer or a cyclic olefin copolymer, while the protective layer is made of ceramic material. The substrate in the contact region is different from the substrate outside the contact region.

Abstract: A coated glass ceramic cooking plate is provided, which has a multilayer coating on its lower surface. The multilayer coating includes a metallic layer of an alloy including components chromium, iron, nickel, and silicon. The silicon content of the alloy is at least 2 atomic percent. This metallic layer is covered by a barrier layer in form of an oxide of an alloy including components chromium, iron, nickel, and silicon, also with a silicon content of at least 2 atomic percent. The molar content of oxygen of the barrier layer is greater by at least a factor of 10 than that of the metallic layer.

Abstract: The invention relates to a composite material (1), to containers made therefrom and to a method for producing the composite material (1), which comprises a substrate (2) and a coating (3) on the substrate (2), wherein the coating (3) provides at least a first region (31) facing the substrate (2) and at least a second region (32) facing away the substrate (2), and wherein the first region (31) comprises a barrier layer (4) and the second region (32) a passivation layer (5).

Abstract: The invention relates to a composite material (1), to containers made therefrom and to a method for producing the composite material (1), which comprises a substrate (2) and a coating (3) on the substrate (2), wherein the coating (3) provides at least a first region (31) facing the substrate (2) and at least a second region (32) facing away the substrate (2), and wherein the first region (31) comprises a barrier layer (4) and the second region (32) a passivation layer (5).

Abstract: An optimized communications system for radio-assisted traffic services such as railroad services. In addition to the fixed-position central services and the fixed-position decentralized control centers, one or more decentralized gateway computers are introduced into the traffic network, with the communication between the mobile objects and the fixed-position objects being provided via the gateway computers.

Abstract: A process for producing an optical device by means of ion exchange is provided. The method includes: coating at least one first region of a substrate with a coating having a first layer of exchange atoms in neutral or ionic form; removing substrate material from at least one second region that adjoins the first region; and exchanging substrate ions with exchange ions from the first layer.