Abstract: A chiral bimetallic cooperative catalysis system containing a chelating ligand and use thereof in asymmetric synthesis of bedaquiline are provided. Specifically, in the chiral bimetallic cooperative catalysis system, an equilibrium constant of a reaction is increased by the chelating ligand formed by an achiral secondary amine and chiral lithium aminoalcohol, thereby promoting an addition reaction between 6-bromo-3-benzyl-2-methoxyquinoline (I) and 3-dimethylamino-1-naphthyl-1-propanone (II) to move forward. By means of the bimetallic cooperative catalysis system, the yield of the target product (1R,2S)-bedaquiline is obviously increased.

Abstract: A chiral bimetallic cooperative catalysis system and use thereof in asymmetric synthesis of bedaquiline are provided. Specifically, the chiral bimetallic cooperative catalysis system is formed by a metallic lithium, sodium or potassium salt and another metal salt under the action of a suitable ligand and an additive. By means of the chiral bimetallic cooperative catalysis system, an addition reaction of 6-bromo-3-benzyl-2-methoxyquinoline (I) and 3-dimethylamino-1-naphthyl-1-propanone (II) is promoted, the selectivity is regulated, and a target product, (1R,2S)-bedaquiline, with high yield and high selectivity is obtained for the first time.

Abstract: A method for detecting and modeling objects in space using LIDAR is disclosed. The method includes transmitting a laser beam to detect at least one object in space. Further, the method includes detecting one or more data related to at least one object. The detection is based upon the principle of reflection of the object in a vacuum. Further, said one or more data related to at least one object obtained from the detection unit is processed. Further, one or more information is determined from the processed data related to at least one object. The one or more information is mapped corresponding to the related at least one object. The method further comprises measuring one or more parameters associated with at least one of the mapped objects and modeling the measurement data related to at least one of the mapped objects.

Abstract: A disinfecting device for purifying air to reduce the presence of dust and/or pathogens. The device includes a main housing, a battery module configured for installation within a first receptacle in the main housing and a reservoir module configured for installation within a second receptacle in the main housing. The reservoir is configured to hold a disinfecting fluid. The housing also includes an ultrasonic wave emitter electrical power communication with the battery, the ultrasonic wave emitter providing ultrasonic waves to the disinfecting fluid thereby creating a pressurized fluid, a membrane in contact with the pressurized fluid. The membrane generates reduced-size particles of the pressurized fluid which are emitted from a nozzle mounted on the housing.

Abstract: A method for detecting and modeling objects in space using LIDAR is disclosed. The method includes transmitting a laser beam to detect at least one object in space. Further, the method includes detecting one or more data related to at least one object. The detection is based upon the principle of reflection of the object in a vacuum. Further, said one or more data related to at least one object obtained from the detection unit is processed. Further, one or more information is determined from the processed data related to at least one object. The one or more information is mapped corresponding to the related at least one object. The method further comprises measuring one or more parameters associated with at least one of the mapped objects and modeling the measurement data related to at least one of the mapped objects.

Abstract: Multiple simultaneous calls are controlled. At least one processor is used to display an interface including indicators corresponding to at least two audio presentation devices. Each interface includes call contextual controls which change according to the state of a call. A swap control swaps an active call between the audio presentation devices corresponding to the indicators.

Abstract: Multiple simultaneous calls are controlled. At least one processor is used to display an interface including indicators corresponding to at least two audio presentation devices. Each interface includes call contextual controls which change according to the state of a call. A swap control swaps an active call between the audio presentation devices corresponding to the indicators.

Abstract: Multiple simultaneous calls are controlled. At least one processor is used to display an interface including indicators corresponding to at least two audio presentation devices. Each interface includes call contextual controls which change according to the state of a call. A swap control swaps an active call between the audio presentation devices corresponding to the indicators.

Abstract: Multiple simultaneous calls are controlled. At least one processor is used to display an interface including indicators corresponding to at least two audio presentation devices. Each interface includes call contextual controls which change according to the state of a call. A swap control swaps an active call between the audio presentation devices corresponding to the indicators.

Abstract: Multiple simultaneous calls are controlled. At least one processor is used to display an interface including indicators corresponding to at least two audio presentation devices. Each interface includes call contextual controls which change according to the state of a call. A swap control swaps an active call between the audio presentation devices corresponding to the indicators.

Abstract: Multiple simultaneous calls are controlled. At least one processor is used to display an interface including indicators corresponding to at least two audio presentation devices. Each interface includes call contextual controls which change according to the state of a call. A swap control swaps an active call between the audio presentation devices corresponding to the indicators.