Patents by Inventor Tanya R. Johnson

Tanya R. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Epoxy-guaiane derivatives and treatment of cancer
    Patent number: 8410292
    Abstract: Disclosed are englerins and derivatives (I) thereof useful in the treatment of a number of cancers, particularly renal cancer, as well as pharmaceutical compositions and method of treating a patient with the use of these derivatives. The englerins, for example Englerin A and Englerin B, can be isolated from the plant Phyllanthus engleri or produced by synthetic methods. An example of the englerin derivative is 2?-chloroenglerin A, which has the structure (II), wherein double bond ‘a’ is E, Z, or a mixture of E and Z.
    Type: Grant
    Filed: December 30, 2008
    Date of Patent: April 2, 2013
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: John A. Beutler, Ranjala Ratnayake, David Covell, Tanya R. Johnson
  • EPOXY-GUAIANE DERIVATIVES AND TREATMENT OF CANCER
    Publication number: 20100286259
    Abstract: Disclosed are englerins and derivatives (I) thereof useful in the treatment of a number of cancers, particularly renal cancer, as well as pharmaceutical compositions and method of treating a patient with the use of these derivatives. The englerins, for example Englerin A and Englerin B, can be isolated from the plant Phyllanthus engleri or produced by synthetic methods. An example of the englerin derivative is 2?-chloroenglerin A, which has the structure (II), wherein double bond ‘a’ is E, Z, or a mixture of E and Z.
    Type: Application
    Filed: December 30, 2008
    Publication date: November 11, 2010
    Applicant: The US, DHHS, NIH
    Inventors: John A. Beutler, Ranjala Ratnayake, David Covell, Tanya R. Johnson