Patents by Inventor Tao Lowe

Tao Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9326953
    Abstract: A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: May 3, 2016
    Assignee: The Penn State Research Foundation
    Inventors: Mark Kester, Thomas Stover, Tao Lowe, James H. Adair, Young Shin Kim
  • Patent number: 9028863
    Abstract: A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: May 12, 2015
    Assignee: The Penn State Research Foundation
    Inventors: Mark Kester, Thomas Stover, Tao Lowe, James H. Adair, Young Shin Kim
  • Publication number: 20130295159
    Abstract: A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.
    Type: Application
    Filed: November 9, 2012
    Publication date: November 7, 2013
    Inventors: Mark Kester, Thomas Stover, Tao Lowe, James H. Adair, Young Shin Kim
  • Publication number: 20050169882
    Abstract: Multifunctional polymers are disclosed having a smart segment and a biodegradable segment. Advantageously, the biodegradable segment includes a hydrophilic segment and a hydrophobic segment. Embodiments include combining the multifunctional polymeric material with a biologically active substance in an aqueous loading environment and administering the composition as a drug delivery vehicle to a human subject.
    Type: Application
    Filed: March 24, 2004
    Publication date: August 4, 2005
    Inventors: Tao Lowe, Young Kim, Xiao Huang
  • Publication number: 20050025820
    Abstract: A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.
    Type: Application
    Filed: April 26, 2004
    Publication date: February 3, 2005
    Inventors: Mark Kester, Thomas Stover, Tao Lowe, James Adair, Young Kim