Patents by Inventor Tao Wen

Tao Wen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12274709
    Abstract: The present invention discloses a dual-drug co-delivery system, a preparation method therefor and use thereof, the dual-drug co-delivery system being prepared from raw materials comprising a block copolymer, Homoharringtonine and Doxorubicin hydrochloride. The dual-drug co-delivery system provided by the present invention has a stronger killing effect on various hematologic tumors and solid tumor cells, can provide a feasible drug delivery system for inhibiting tumor growth and leukemia treatment, and has broad prospects.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: April 15, 2025
    Assignee: INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES
    Inventors: Haiyan Xu, Doudou Yan, Jie Meng, Jian Liu, Tao Wen, Yangyang Ge
  • Patent number: 11976300
    Abstract: Disclosed is the use of a water-soluble realgar solid dispersion in the preparation of an erythroid differentiation inducer for bone marrow hematopoietic stem cells and/or bone marrow hematopoietic progenitor cells. The water-soluble realgar solid dispersion is prepared from raw materials comprising 1 part by weight of realgar, 1-20 parts by weight of a polymer, and 0-5 parts by weight of a surfactant. The water-soluble realgar solid dispersion can induce bone marrow hematopoietic stem and/or progenitor cells to be differentiated into red blood cells, promote the accumulation of red blood cells in bone marrow cells, effectively alleviate the decrease in the number of red blood cells caused by the suppression of the erythroid differentiation of bone marrow hematopoietic stem and/or progenitor cells, improve anemia caused by hematopoietic failure, and protect bone marrow cells from the killing effect.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: May 7, 2024
    Assignee: INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES
    Inventors: Haiyan Xu, Jian Liu, Tao Wang, Bing Han, Jie Meng, Tao Wen
  • Patent number: 11947438
    Abstract: Embodiments of the present disclosure provide an operation and maintenance system and method. The operation and maintenance system comprises a plurality of interconnected modules including: a data acquisition module, a data storage module, an exception and fault labeling module, an automatic model training and assessment module, an operation and maintenance management and task execution module, and a result checking module.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: April 2, 2024
    Assignee: XI'AN ZHONGXING NEW SOFTWARE CO., LTD.
    Inventors: Lixia Liu, Feng Ji, Tao Wen
  • Patent number: 11947982
    Abstract: A plurality of constraint relationships in a UI are identified and grouped into two types, a constraint relationship of a first type is solved in an integrated development environment (IDE), and a constraint relationship of a second type is a constraint relationship solved in a terminal or the IDE. The plurality of constraint relationships are used to determine a layout of one or more components in the UI. The IDE calculates a first intermediate solution set based on the constraint relationship of the first type in the plurality of constraint relationships. The first intermediate solution set is used to determine the layout of the one or more components in the UI together with the constraint relationship of the second type.
    Type: Grant
    Filed: July 13, 2023
    Date of Patent: April 2, 2024
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Tao Wen, Xiao Xu, Jun Liu, Tengfei Cui
  • Publication number: 20240095236
    Abstract: Disclosed are a method and system for transaction management, a network device, and a readable storage medium. The method includes the following. A coordinating node receives a structured query language (SQL) request externally initiated, where the SQL request is forwarded by a master node. The coordinating node decomposes the SQL request into sub-SQL (SubSQL) requests, and transmits each of the SubSQL requests to a corresponding slave node. Each slave node receives and processes a corresponding SubSQL request, transmits execution status information of the corresponding SubSQL request to the coordinating node and/or other slave nodes, and receives execution status information in processing respective SubSQL requests by the other slave nodes. Each particular slave node of one or more of the slave nodes feeds back a current local transaction status set of the particular slave node according to status query information received from the master node or the coordinating node.
    Type: Application
    Filed: September 30, 2020
    Publication date: March 21, 2024
    Inventors: Tao WEN, Da LV, Han ZHANG
  • Publication number: 20230350702
    Abstract: A plurality of constraint relationships in a UI are identified and grouped into two types, a constraint relationship of a first type is solved in an integrated development environment (IDE), and a constraint relationship of a second type is a constraint relationship solved in a terminal or the IDE. The plurality of constraint relationships are used to determine a layout of one or more components in the UI. The IDE calculates a first intermediate solution set based on the constraint relationship of the first type in the plurality of constraint relationships. The first intermediate solution set is used to determine the layout of the one or more components in the UI together with the constraint relationship of the second type.
    Type: Application
    Filed: July 13, 2023
    Publication date: November 2, 2023
    Inventors: Tao Wen, Xiao Xu, Jun Liu, Tengfei Cui
  • Publication number: 20230350709
    Abstract: Disclosed are a cloud safety computing method, a device and a storage medium based on cloud fault-tolerant technology. The cloud safety computing method includes following steps: S1, adopting a one-master multiple-slave fault-tolerant architecture for management nodes, and using KeepAlived and Haproxy to realize a liveness self-check of the management nodes and a load balancing of user requests, and S2, adopting a dynamic redundancy fault-tolerant safety design for service nodes to maintain a life cycle of application microservices, and giving feedback on liveness information to the management nodes in real time through heartbeat by the service nodes, where the application microservices report the life cycle to the management nodes based on a probe mechanism, and the application microservices exchange input and output information through redundancy voting.
    Type: Application
    Filed: July 22, 2022
    Publication date: November 2, 2023
    Inventors: Li ZHU, Song LI, Tao TANG, Xi WANG, Hongwei WANG, Tao WEN
  • Patent number: 11795490
    Abstract: Disclosed are apparatus, method and system for monitoring mold based on weak electrical signals. The apparatus comprises a mold collector, a power supply, a trans-impedance amplifier, and an analog-to-digital converter, wherein the mold collector is smeared with a trophoplasm, and a substrate of the mold collector has electrical conductivity, the power supply is used for applying a voltage to the substrate of the mold collector, the trans-impedance amplifier is used for amplifying a weak current generated from the substrate of the mold collector to a voltage signal, and the analog-to-digital converter is used for converting the voltage signal amplified by the trans-impedance amplifier into a digital signal for determining the quantity of molds.
    Type: Grant
    Filed: June 10, 2021
    Date of Patent: October 24, 2023
    Assignee: GUANGZHOU UNIVERSITY
    Inventors: Zhaosong Fang, Zhangyi Xie, Zhimin Zheng, Tao Wen
  • Patent number: 11762939
    Abstract: An approach is disclosed that determines an amount of time before a webpage is ready to use by a user by performing various actions. The approach captures a recording of the webpage from an invocation of the webpage for a period of time sufficient to load completely load the webpage with the capturing resulting in sequenced image frames. An AI system provides a loading point in the sequenced image frames based on an analysis of the frames input to the trained AI system. Image diversity and saturation measurements are calculated on consecutive image frames from the sequenced image frames resulting in an image change analysis. Native webpage events and times are detected from webpage characteristics gathered from the captured digital recording. The amount of time is then calculated based on the loading point from the AI system, the image change analysis; and the webpage events and their corresponding times.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: September 19, 2023
    Assignee: International Business Machines Corporation
    Inventors: Ling Zhuo, Pei Pei Liang, Lin Yan Wu, Li Zhou, Yue Yang, Yun Bo Zhang, Tao Wen
  • Publication number: 20230250183
    Abstract: The invention discloses a polypeptide that specifically binding to CD123 protein, a polypeptide complex and a co-delivery system, and preparation methods and use thereof. The general formula of amino acid arrangement in the polypeptide is X1-DYDTR-X2-QGTD-X3-G-X4-DFRRISD-X5; it can bind to CD123-positive cells and inhibit the progression of leukemia; the polypeptide complex can increase the binding quantity of the polypeptide to CD123-positive cells, and drug can inhibit the progression of leukemia alone and prolong the survival of leukemia mice; the co-delivery system can load chemotherapy drugs for tumor treatment and reduce the toxicity of chemotherapy drugs to normal cells.
    Type: Application
    Filed: June 22, 2021
    Publication date: August 10, 2023
    Inventors: Haiyan XU, Chen WANG, Shilin XU, Yanlian YANG, Jie MENG, Jian LIU, Tao WEN
  • Patent number: 11719838
    Abstract: In an array-type underwater apparatus for monitoring deformation of a reservoir landslide, an anchor is buried at an underwater monitoring point in a landslide mass, and a floating shell is configured to float on a water surface. A GPS sensor is configured to transmit and receive a GPS signal to obtain a real-time position of the floating shell, a water temperature sensor is used to obtain a water temperature-time relationship, and a gravity wave gauge is used to obtain a wave height-time relationship. An upper end of a pull cord is securely connected to the floating shell via a displacement compensation mechanism, and a lower end of the pull cord is securely connected to the anchor. The displacement compensation mechanism compensates for a displacement after the floating shell floats with a wave. An encoder-type displacement meter measures a real-time distance between the encoder-type displacement meter and the anchor.
    Type: Grant
    Filed: June 3, 2021
    Date of Patent: August 8, 2023
    Assignee: CHINA UNIVERSITY OF GEOSCIENCES (WUHAN)
    Inventors: Junrong Zhang, Huiming Tang, Yongquan Zhang, Chengyuan Lin, Dwayne Tannant, Changdong Li, Tao Wen, Bocheng Zhang, Sixuan Sun
  • Patent number: 11657216
    Abstract: Aspects of the present disclosure relate to input text management. Input text can be received from a user. A set of key elements can be extracted from the input text. A determination can be made whether the user is mapped to an existing cluster. In response to determining that the user is mapped to an existing cluster, a structured table mapping key elements to text modifications can be referenced. The input text can be modified according to the structured table mapping key elements to text modifications, wherein the existing cluster is associated with a text modification scheme within the structured table, wherein the text modification scheme includes a first mapping of key elements to text modifications.
    Type: Grant
    Filed: May 20, 2021
    Date of Patent: May 23, 2023
    Assignee: International Business Machines Corporation
    Inventors: Fei Fan, Lin Yan Wu, Xue Ying Zhang, Jing Xu, Yan Yan Han, Yun Bo Zhang, Tao Wen
  • Publication number: 20230063608
    Abstract: An approach is disclosed that determines an amount of time before a webpage is ready to use by a user by performing various actions. The approach captures a recording of the webpage from an invocation of the webpage for a period of time sufficient to load completely load the webpage with the capturing resulting in sequenced image frames. An AI system provides a loading point in the sequenced image frames based on an analysis of the frames input to the trained AI system. Image diversity and saturation measurements are calculated on consecutive image frames from the sequenced image frames resulting in an image change analysis. Native webpage events and times are detected from webpage characteristics gathered from the captured digital recording. The amount of time is then calculated based on the loading point from the AI system, the image change analysis; and the webpage events and their corresponding times.
    Type: Application
    Filed: August 25, 2021
    Publication date: March 2, 2023
    Inventors: Ling Zhuo, Pei Pei Liang, Lin Yan Wu, Li Zhou, Yue Yang, Yun Bo Zhang, Tao Wen
  • Publication number: 20220374587
    Abstract: Aspects of the present disclosure relate to input text management. Input text can be received from a user. A set of key elements can be extracted from the input text. A determination can be made whether the user is mapped to an existing cluster. In response to determining that the user is mapped to an existing cluster, a structured table mapping key elements to text modifications can be referenced. The input text can be modified according to the structured table mapping key elements to text modifications, wherein the existing cluster is associated with a text modification scheme within the structured table, wherein the text modification scheme includes a first mapping of key elements to text modifications.
    Type: Application
    Filed: May 20, 2021
    Publication date: November 24, 2022
    Inventors: Fei Fan, Lin Yan Wu, Xue Ying Zhang, Jing Xu, Yan Yan Han, Yun Bo Zhang, Tao Wen
  • Publication number: 20220334278
    Abstract: In an array-type underwater apparatus for monitoring deformation of a reservoir landslide, an anchor is buried at an underwater monitoring point in a landslide mass, and a floating shell is configured to float on a water surface. A GPS sensor is configured to transmit and receive a GPS signal to obtain a real-time position of the floating shell, a water temperature sensor is used to obtain a water temperature-time relationship, and a gravity wave gauge is used to obtain a wave height-time relationship. An upper end of a pull cord is securely connected to the floating shell via a displacement compensation mechanism, and a lower end of the pull cord is securely connected to the anchor. The displacement compensation mechanism compensates for a displacement after the floating shell floats with a wave. An encoder-type displacement meter measures a real-time distance between the encoder-type displacement meter and the anchor.
    Type: Application
    Filed: June 3, 2021
    Publication date: October 20, 2022
    Applicant: CHINA UNIVERSITY OF GEOSCIENCES (WUHAN)
    Inventors: Junrong ZHANG, Huiming TANG, Yongquan ZHANG, Chengyuan LIN, Dwayne Tannant, Changdong LI, Tao WEN, Bocheng ZHANG, Sixuan SUN
  • Publication number: 20220127656
    Abstract: Disclosed are apparatus, method and system for monitoring mold based on weak electrical signals. The apparatus comprises a mold collector, a power supply, a trans-impedance amplifier, and an analog-to-digital converter, wherein the mold collector is smeared with a trophoplasm, and a substrate of the mold collector has electrical conductivity, the power supply is used for applying a voltage to the substrate of the mold collector, the trans-impedance amplifier is used for amplifying a weak current generated from the substrate of the mold collector to a voltage signal, and the analog-to-digital converter is used for converting the voltage signal amplified by the trans-impedance amplifier into a digital signal for determining the quantity of molds.
    Type: Application
    Filed: June 10, 2021
    Publication date: April 28, 2022
    Inventors: Zhaosong FANG, Zhangyi XIE, Zhimin ZHENG, Tao WEN
  • Publication number: 20220047613
    Abstract: The present invention discloses a dual-drug co-delivery system, a preparation method therefor and use thereof, the dual-drug co-delivery system being prepared from raw materials comprising a block copolymer, Homoharringtonine and Doxorubicin hydrochloride. The dual-drug co-delivery system provided by the present invention has a stronger killing effect on various hematologic tumors and solid tumor cells, can provide a feasible drug delivery system for inhibiting tumor growth and leukemia treatment, and has broad prospects.
    Type: Application
    Filed: February 27, 2020
    Publication date: February 17, 2022
    Applicant: Institute of Basic Medical Sciences Chinese Academy of Medical Sciences
    Inventors: Haiyan XU, Doudou YAN, Jie MENG, Jian LIU, Tao WEN, Yangyang GE
  • Publication number: 20210271582
    Abstract: Embodiments of the present disclosure provide an operation and maintenance system and method. The operation and maintenance system comprises a plurality of interconnected modules including: a data acquisition module, a data storage module, an exception and fault labeling module, an automatic model training and assessment module, an operation and maintenance management and task execution module, and a result checking module.
    Type: Application
    Filed: June 28, 2019
    Publication date: September 2, 2021
    Inventors: Lixia LIU, Feng JI, Tao WEN
  • Publication number: 20210155901
    Abstract: Disclosed is the use of a water-soluble realgar solid dispersion in the preparation of an erythroid differentiation inducer for bone marrow hematopoietic stem cells and/or bone marrow hematopoietic progenitor cells. The water-soluble realgar solid dispersion is prepared from raw materials comprising 1 part by weight of realgar, 1-20 parts by weight of a polymer, and 0-5 parts by weight of a surfactant. The water-soluble realgar solid dispersion can induce bone marrow hematopoietic stem and/or progenitor cells to be differentiated into red blood cells, promote the accumulation of red blood cells in bone marrow cells, effectively alleviate the decrease in the number of red blood cells caused by the suppression of the erythroid differentiation of bone marrow hematopoietic stem and/or progenitor cells, improve anemia caused by hematopoietic failure, and protect bone marrow cells from the killing effect.
    Type: Application
    Filed: April 11, 2019
    Publication date: May 27, 2021
    Inventors: Haiyan XU, Jian LIU, Tao WANG, Bing HAN, Jie MENG, Tao WEN
  • Patent number: 10769270
    Abstract: A method and an apparatus for setting a password protection question are disclosed. The method includes: receiving a password protection question set request for a password, the set request including a user identifier; extracting one or more pieces of setting information corresponding to the user identifier; individually acquiring one or more password protection questions that match the one or more pieces of setting information; and outputting the one or more password protection questions. The embodiments of the present disclosure can output password protection questions related to preference or interest of a user when the user sets a password protection question, which reinforces the impression of the user on the password protection question, thereby reducing situations that the user forgets the set password protection question and an answer thereof, and improving the practicability of the password protection question.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: September 8, 2020
    Assignee: Alibaba Group Holding Limited
    Inventor: Tao Wen